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http://www.chinagp.net E-mail:zgqkyx@chinagp.net.cn ·2235·
·论著·宫颈癌专题研究·
宫颈癌淋巴结的评估与手术策略探讨
张清泉,王世军 * 扫描二维码
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【摘要】 宫颈癌是妇科常见的恶性肿瘤之一。手术治疗是早期宫颈癌的重要治疗方式。宫颈癌患者是否存在淋
巴结转移对评估宫颈癌预后及治疗方案的选择具有重要的意义,而术前根据淋巴结转移的相关危险因素及影像学检查
结果评估淋巴结转移的情况,有助于临床制订手术策略。近年来,前哨淋巴结活检术因其安全性及可行性已被推荐应
用于早期宫颈癌患者的手术治疗,可根据宫颈癌患者术前淋巴结评估情况选择性地进行前哨淋巴结活检、系统性淋巴
结切除及腹主动脉旁淋巴结切除,根据术中淋巴结转移情况可制订相应的手术切除范围。因此,宫颈癌淋巴结的评估
尤其是手术策略的制订在宫颈癌治疗中具有重要的意义。
【关键词】 宫颈肿瘤;淋巴结评估;前哨淋巴结;前哨淋巴结活组织检查;手术策略
【中图分类号】 R 737.33 【文献标识码】 A DOI:10.12114/j.issn.1007-9572.2021.02.111
张清泉,王世军 . 宫颈癌淋巴结的评估与手术策略探讨[J]. 中国全科医学,2022,25(18):2235-2238. [www.
chinagp.net]
ZHANG Q Q,WANG S J. Assessment and surgical strategies for lymphatic metastasis in cervical cancer[J]. Chinese
General Practice,2022,25(18):2235-2238.
Assessment and Surgical Strategies for Lymphatic Metastasis in Cervical Cancer ZHANG Qingquan,WANG Shijun *
Department of Gynaecology and Obstetrics,Xuanwu Hospital,Capital Medical University,Beijing 100053,China
*
Corresponding author:WANG Shijun,Professor,Doctoral supervisor;E-mail:wsj9188@126.com
【Abstract】 Cervical cancer is a common gynecologic malignant tumor. Surgical treatment is an important treatment for
early stage cervical cancer. Whether having lymph node metastasis is of great significance to the assessment of the prognosis of
cervical cancer and the choice of treatment options. Preoperative assessment of lymph node metastasis based on identified related
risk factors and imaging findings is helpful to the formulation of surgical strategies. In recent years,sentinel lymph node biopsy
has been recommended for surgical treatment of patients with early stage cervical cancer due to its safety and feasibility. Patients
with cervical cancer can selectively undergo sentinel lymph node biopsy,systematic lymph node resection,or para-aortic lymph
node resection based on their preoperative lymph node assessment. According to intraoperative diagnosis of the degree of lymph
node involvement,the extent of surgical resection can be determined. So the assessment of lymphatic metastasis,especially the
formulation of surgical strategieswere of great significance in the treatment of cervical cancer.
【Key words】 Uterine cervical neoplasms;Lymph node assessment;Sentinel lymph node;Sentinel lymph node
biopsy;Surgical strategy
宫颈癌是妇科常见的恶性肿瘤之一,是全球女性第 策略。本文就宫颈癌患者淋巴结评估及手术策略的相关
4 大常见肿瘤 [1] 。宫颈癌是发展中国家女性癌症死亡 问题进行阐述。
的主要原因,尽管近年来宫颈癌研究不断进展,但全球 1 淋巴结与宫颈癌
宫颈癌的发病率及死亡率仍有上升趋势。对于早期宫颈 盆腔淋巴结切除是早期宫颈癌患者手术治疗的重要
癌患者来说,手术治疗是重要的治疗方式。广泛性子宫 组成部分。对于宫颈癌患者来说,淋巴结是否转移已纳
切除和盆腔淋巴结切除是早期宫颈浸润癌常用的手术方 入国际妇产科联盟(FIGO)新的分期标准,可用于指
式。对于高危患者,还需要切除腹主动脉旁淋巴结。淋 导术后辅助治疗方案的制订,且与患者预后密切相关。
巴结的评估有助于临床医生评估患者病情,并制订手术 有研究显示,淋巴结转移是影响宫颈癌患者预后的重要
危险因素 [2-3] 。存在淋巴结转移的宫颈癌患者复发率、
100053 北京市,首都医科大学宣武医院妇产科 远处转移治疗失败率较高,因此可以认为伴淋巴结转移
*
通信作者:王世军,教授,博士生导师;
E-mail:wsj9188@126.com 的宫颈癌属于全身性疾病,手术治疗后仍需辅助进行术
本文数字出版日期:2021-11-18 后化疗 [4] 。此外,腹主动脉旁淋巴结转移是宫颈癌复