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Epidemiol,2013,177(9):1006-1014. DOI:10.1093/aje/ Endocrinol,2014,392(1/2):106-114. DOI:10.1016/j.
kws342. mce.2014.05.012.
[2]DRAGER L F,POLOTSKY V Y,DONNELL C P,et al. [15]YUAN H B,SCHWAB R J,KIM C,et al. Relationship between
Translational approaches to understanding metabolic dysfunction and body fat distribution and upper airway dynamic function during sleep
cardiovascular consequences of obstructive sleep apnea[J]. Am J in adolescents[J]. Sleep,2013,36(8):1199-1207. DOI:
Physiol Heart Circ Physiol,2015,309(7):H1101-1111. DOI: 10.5665/sleep.2886.
10.1152/ajpheart.00094.2015. [16]LI M,LI X Y,LU Y. Obstructive sleep apnea syndrome and
[3]LAVIE L,VISHNEVSKY A,LAVIE P. Evidence for lipid metabolic diseases[J]. Endocrinology,2018,159(7):
peroxidation in obstructive sleep apnea[J]. Sleep,2004,27(1): 2670-2675. DOI:10.1210/en.2018-00248.
123-128. [17]FU C,JIANG L,ZHU F,et al. Chronic intermittent hypoxia
[4]SONG S O,HE K,NARLA R R,et al. Metabolic consequences of leads to insulin resistance and impaired glucose tolerance through
obstructive sleep apnea especially pertaining to diabetes mellitus and dysregulation of adipokines in non-obese rats[J]. Sleep Breath,
insulin sensitivity[J]. Diabetes Metab J,2019,43(2):144- 2015,19(4):1467-1473. DOI:10.1007/s11325-015-1144-8.
155. DOI:10.4093/dmj.2018.0256. [18]ULUKAVAK CIFTCI T,KOKTURK O,BUKAN N,et al.
[5]BARROS D,GARCÍA-RÍO F. Obstructive sleep apnea and Leptin and ghrelin levels in patients with obstructive sleep apnea
dyslipidemia:from animal models to clinical evidence[J]. Sleep, syndrome[J]. Respiration,2005,72(4):395-401. DOI:
2019,42(3):zsy236. DOI:10.1093/sleep/zsy236. 10.1159/000086254.
[6]SAVRANSKY V,JUN J,LI J,et al. Dyslipidemia and [19]MOREAU J M,MESSENGER S A,CIRIELLO J. Effects of
atherosclerosis induced by chronic intermittent hypoxia are angiotensin II on leptin and downstream leptin signaling in the
attenuated by deficiency of stearoyl coenzyme A desaturase[J]. carotid body during acute intermittent hypoxia[J]. Neuroscience,
Circ Res,2008,103(10):1173-1180. DOI: 2015,310:430-441. DOI:10.1016/j.neuroscience.2015.09.066.
10.1161/circresaha.108.178533. [20]CHEN B Y,LAM K S,WANG Y,et al. Hypoxia dysregulates
2+
[7]YUAN G,NANDURI J,BHASKER C R,et al. Ca /calmodulin the production of adiponectin and plasminogen activator inhibitor-1
kinase-dependent activation of hypoxia inducible factor 1 independent of reactive oxygen species in adipocytes[J]. Biochem
transcriptional activity in cells subjected to intermittent hypoxia[J]. Biophys Res Commun,2006,341(2):549-556. DOI:
J Biol Chem,2005,280(6):4321-4328. DOI:10.1074/jbc. 10.1016/j.bbrc.2006.01.004.
m407706200. [21] POLYZOS S A,KOUNTOURAS J,MANTZOROS C S. Adipokines
[8]SANZ-RUBIO D,SANZ A,VARONA L,et al. Forkhead in nonalcoholic fatty liver disease[J]. Metabolism,2016,65(8):
box P3 methylation and expression in men with obstructive sleep 1062-1079. DOI:10.1016/j.metabol.2015.11.006.
apnea[J].Int J Mol Sci,2020,21(6):E2233. DOI: [22]GREENHILL C. Obesity:Adiponectin receptor agonists——
10.3390/ijms21062233. possible therapeutic approach ?[J]. Nat Rev Endocrinol,
[9]SUN Z,SHEN W. Effect of intermittent hypoxia on lipid metabolism 2014,10(1):4. DOI:10.1038/nrendo.2013.231.
in liver cells and the underlying mechanism[J]. Chinese Journal [23]OUCHI N,HIGUCHI A,OHASHI K,et al. Sfrp5 is an anti-
of Hepatology,2014,22(5):369-373. DOI:10.3760/cma. inflammatory adipokine that modulates metabolic dysfunction in
j.issn.1007-3418.2014.05.010. obesity[J]. Science,2010,329(5990):454-457. DOI:
[10]PARIKH M P,GUPTA N M,MCCULLOUGH A J. Obstructive 10.1126/science.1188280.
sleep apnea and the liver[J].Clin Liver Dis,2019,23(2): [24]SUN S,ZHAI H,ZHU M,et al. Insulin resistance is
363-382. DOI:10.1016/j.cld.2019.01.001. associated with Sfrp5 in obstructive sleep apnea[J]. Braz J
[11]YUAN H B,SCHWAB R J,KIM C,et al. Relationship between Otorhinolaryngol,2019,85(6):739-745. DOI:10.1016/j.
body fat distribution and upper airway dynamic function during sleep bjorl.2018.07.002.
in adolescents[J]. Sleep,2013,36(8):1199-1207. DOI: [25]POLAK J,SHIMODA L A,DRAGER L F,et al. Intermittent
10.5665/sleep.2886. hypoxia impairs glucose homeostasis in C57BL6/J mice:partial
[12]BOZKURT N C,BEYSEL S,KARBEK B,et al. Visceral obesity improvement with cessation of the exposure[J]. Sleep,2013,36
mediates the association between metabolic syndrome and obstructive (10):1483-1490;1490A-1490B. DOI:10.5665/sleep.3040.
sleep apnea syndrome[J]. Metab Syndr Relat Disord,2016,14(4): [26]XIA Q S,LU F E,WU F,et al. New role for ceramide in hypoxia
217-221. DOI:10.1089/met.2015.0086. and insulin resistance[J]. World J Gastroenterol,2020,26(18):
[13]LAFONTAN M,LANGIN D. Lipolysis and lipid mobilization in 2177-2186. DOI:10.3748/wjg.v26.i18.2177.
human adipose tissue[J]. Prog Lipid Res,2009,48(5): [27]BROUSSARD J,BRADY M J. The impact of sleep disturbances on
275-297. DOI:10.1016/j.plipres.2009.05.001. adipocyte function and lipid metabolism[J]. Best Pract Res Clin
[14]XIONG Y L,QU Z,CHEN N,et al. The local corticotropin- Endocrinol Metab,2010,24(5):763-773. DOI:10.1016/j.
releasing hormone receptor 2 signalling pathway partly mediates beem.2010.08.007.
hypoxia-induced increases in lipolysis via the cAMP-protein [28]NONOGAKI K. New insights into sympathetic regulation of glucose
kinase A signalling pathway in white adipose tissue[J]. Mol Cell and fat metabolism[J]. Diabetologia,2000,43(5):533-