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2023年2月 第26卷 第5期 http: //www.chinagp.net E-mail: zgqkyx@chinagp.net.cn ·563·
·论著·
基于正念的补充替代疗法对妊娠期糖尿病孕妇血糖水平
和炎性因子及脂肪因子的影响研究
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舒玲 ,龚波 ,王婧 ,粟艳林 2 查看原文
【摘要】 背景 妊娠期糖尿病(GDM)的发病率居高不下,且在全球普遍流行,在中国 GDM 发生率高达
14.8%,妊娠期高血糖严重威胁母婴健康。目的 探讨 GDM 孕妇采用基于正念的补充替代疗法的干预效果。方法
2021 年 3—12 月采用便利抽样法选取在长沙市中心医院门诊进行产前检查的 64 例 GDM 孕妇,采用随机数字表法分为
试验组(n=31)和对照组(n=33)。对照组采取常规心理护理、饮食宣教、运动指导,试验组在常规心理护理基础上
采用 8 周基于正念的补充替代疗法。收集患者基线资料,比较两组孕妇干预前后血糖水平及炎性因子、丝氨酸蛋白抑
制剂(vaspin)水平,随访新生儿结局指标(出生体质量、随机血糖)。结果 干预后试验组孕妇空腹血糖、餐后 1 h
血糖、餐后 2 h 血糖、白介素 6、白介素 8、肿瘤坏死因子 α、vaspin 水平低于对照组(P<0.05);干预后试验组空腹血糖、
餐后 1 h 血糖、餐后 2 h 血糖、白介素 6、白介素 8、肿瘤坏死因子 α、vaspin 低于干预前(P<0.05);试验组 GDM
孕妇分娩时体质量、分娩时体质指数、妊娠期增重、分娩前糖化血红蛋白,新生儿出生体质量均低于对照组(P<0.05),
试验组新生儿随机血糖高于对照组(P<0.05)。结论 对GDM孕妇给予8周基于正念的补充替代疗法可降低其体质指数,
有效控制血糖,降低炎性因子及脂肪因子水平,减少新生儿低血糖的发生。
【关键词】 糖尿病,妊娠;补充与替代医学;正念;炎症;脂肪因子;肿瘤坏死因子 α
【中图分类号】 R 714.256 【文献标识码】 A DOI:10.12114/j.issn.1007-9572.2022.0496
舒玲,龚波,王婧,等 . 基于正念的补充替代疗法对妊娠期糖尿病孕妇血糖水平及和炎性因子及脂肪因子的影响
研究[J]. 中国全科医学,2023,26(5):563-568,582. [www.chinagp.net]
SHU L,GONG B,WANG J,et al. Effects of complementary and alternative therapy of mindfulness on blood sugar and
inflammatory biomarkers and adipokines in pregnant women with gestational diabetes mellitus[J]. Chinese General Practice,
2023,26(5):563-568,582.
Effects of Complementary and Alternative Therapy of Mindfulness on Blood Sugar and Inflammatory Biomarkers and
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Adipokines in Pregnant Women with Gestational Diabetes Mellitus SHU Ling ,GONG Bo ,WANG Jing ,SU Yanlin 2
1.Department of Otorhinolaryngology Head and Neck Surgery,Changsha Central Hospital/the Affiliated Changsha Central
Hospital,University of South China,Changsha 410004,China
2.Department of Obstetrics and Gynecology,Changsha Central Hospital/the Affiliated Changsha Central Hospital,University of
South China,Changsha 410004,China
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Corresponding author:GONG Bo,Deputy chief nurse;E-mail:664941353@qq.com
【Abstract】 Background The incidence of gestational diabetes mellitus (GDM) remains high,and it is prevalent
all over the world. The incidence of GDM in China is up to 14.8%. Intrauterine hyperglycemia during pregnancy is a severe threat
to maternal and neonatal health. Objective The aim of this study was to evaluate the effect of mindfulness-based complementary
and alternative therapy for GDM. Methods This study selected 64 pregnant women with GDM undergoing routine outpatient
prenatal examination in Changsha Central Hospital by using convenience sampling from March to December 2021. These patients
were randomly assigned into the intervention group(n=31) and the control group(n=33). The control group received routine
psychologicalgcare,nutritional guidance and exercise guidance. The intervention group received 8 weeks of mindfulness-based
complementary and alternative therapy on the basis of routine psychological care. This study collected the baseline characteristics
and compared the blood sugar and inflammatory biomarkers and adipokines,followed-up neonatal outcomes(birth weight,
基金项目:湖南省卫生健康委科研计划课题项目(C20201237)
1.410004 湖南省长沙市中心医院 南华大学附属长沙中心医院耳鼻咽喉头颈外科
2.410004 湖南省长沙市中心医院 南华大学附属长沙中心医院妇产科
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通信作者:龚波,副主任护师;E-mail:664941353@qq.com
本文数字出版日期:2022-09-30