Page 117 - 2023-06-中国全科医学
P. 117

·758·  http: //www.chinagp.net   E-mail: zgqkyx@chinagp.net.cn                    February  2023, Vol.26  No.6

           [13]SIITERI P K. Adipose tissue as a source of hormones[J].   PPARgamma2 expression in adipocytes[J]. Am J Physiol Regul
               Am  J  Clin  Nutr,1987,45(1  Suppl):277-282.  DOI:   Integr Comp Physiol,2005,288(5):R1220-1225. DOI:
               10.1093/ajcn/45.1.277.                               10.1152/ajpregu.00397.2004.
           [14]ZHANG Y,PROENCA R,MAFFEI M,et al. Positional cloning   [27]MAEDA N,SHIMOMURA I,KISHIDA K,et al. Diet-induced
               of the mouse obese gene and its human homologue[J]. Nature,  insulin resistance in mice lacking adiponectin/ACRP30[J]. Nat
               1994,372(6505):425-432. DOI:10.1038/372425a0.        Med,2002,8(7):731-737. DOI:10.1038/nm724.
           [15]KADOWAKI T,YAMAUCHI T,KUBOTA N,et al. Adiponectin   [28]HANSON C,RUTTEN E P,WOUTERS E F,et al. Influence
               and adiponectin receptors in insulin resistance,diabetes,and the   of diet and obesity on COPD development and outcomes[J].
               metabolic syndrome[J]. J Clin Invest,2006,116(7):1784-  Int J Chron Obstruct Pulmon Dis,2014,9:723-733. DOI:
               1792. DOI:10.1172/JCI29126.                          10.2147/COPD.S50111.
           [16]KADOWAKI T,YAMAUCHI T. Adiponectin and adiponectin   [29]CHEN H P,LI Z Y,DONG L L,et al. Lipid metabolism in
               receptors[J]. Endocr Rev,2005,26(3):439-451. DOI:    chronic obstructive pulmonary disease[J]. Int J Chron Obstruct
               10.1210/er.2005-0005.                                Pulmon Dis,2019,14:1009-1018. DOI:10.2147/COPD.
           [17]DANIELE A,DE ROSA A,NIGRO E,et al. Adiponectin       S196210.
               oligomerization state and adiponectin receptors airway expression   [30]YOON M J,LEE G Y,CHUNG J J,et al. Adiponectin increases
               in chronic obstructive pulmonary disease[J]. Int J Biochem   fatty acid oxidation in skeletal muscle cells by sequential activation
               Cell  Biol,2012,44(3):563-569.  DOI:10.1016/j.       of AMP-activated protein kinase,p38 mitogen-activated protein
               biocel.2011.12.016.                                  kinase,and peroxisome proliferator-activated receptor alpha[J].
           [18]THYAGARAJAN B,JACOBS D R Jr,SMITH L J,et al. Serum   Diabetes,2006,55(9):2562-2570. DOI:10.2337/db05-
               adiponectin is positively associated with lung function in young   1322.
               adults,independent of obesity:the CARDIA study[J]. Respir   [31]TOMAS E,TSAO T S,SAHA A K,et al. Enhanced muscle fat
               Res,2010,11:176. DOI:10.1186/1465-9921-11-176.       oxidation and glucose transport by ACRP30 globular domain:
           [19]NAKANISHI K,TAKEDA Y,TETSUMOTO S,et al. Involvement   acetyl-CoA carboxylase inhibition and AMP-activated protein
               of endothelial apoptosis underlying chronic obstructive pulmonary   kinase activation[J]. Proc Natl Acad Sci USA,2002,99(25):
               disease-like phenotype in adiponectin-null mice:implications for   16309-16313. DOI:10.1073/pnas.222657499.
               therapy[J]. Am J Respir Crit Care Med,2011,183(9):  [32]YAMAUCHI T,NIO Y,MAKI T,et al. Targeted disruption of
               1164-1175. DOI:10.1164/rccm.201007-1091OC.           AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and
           [20]SUN Y,AN N,LI J S,et al. miRNA-206 regulates human   metabolic actions[J]. Nat Med,2007,13(3):332-339.
               pulmonary microvascular endothelial cell apoptosis via targeting   DOI:10.1038/nm1557.
               in chronic obstructive pulmonary disease[J]. J Cell Biochem,  [33]AWAZAWA  M,UEKI  K,INABE  K,et  al.  Adiponectin
               2019,120(4):6223-6236. DOI:10.1002/jcb.27910.        suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/
           [21]XIA S Y,QU J,JIA H,et al. Overexpression of Forkhead box C1   AMPK dependent pathway[J]. Biochem Biophys Res Commun,
               attenuates oxidative stress,inflammation and apoptosis in chronic   2009,382(1):51-56. DOI:10.1016/j.bbrc.2009.02.131.
               obstructive pulmonary disease[J]. Life Sci,2019,216:75-84.   [34]AHIMA R S,FLIER J S. Leptin[J]. Annu Rev Physiol,2000,
               DOI:10.1016/j.lfs.2018.11.023.                       62:413-437. DOI:10.1146/annurev.physiol.62.1.413.
           [22]ZHOU X,YI D J,WU Y H,et al. Expression of diaphragmatic   [35]MYERS M G,COWLEY M A,MÜNZBERG H. Mechanisms of
               myostatin and correlation with apoptosis in rats with chronic   leptin action and leptin resistance[J]. Annu Rev Physiol,2008,
               obstructive pulmonary disease[J]. Exp Ther Med,2018,15(3):  70:537-556. DOI:10.1146/annurev.physiol.70.113006.100707.
               2295-2300. DOI:10.3892/etm.2018.5686.           [36]UZUN H,UYSAL P. Evaluation of ghrelin and leptin in chronic
           [23]JIANG M X,QI L,LI L S,et al. The caspase-3/GSDME     obstructive pulmonary disease[J]. Eurasian J Pulmonol,2019,
               signal pathway as a switch between apoptosis and pyroptosis in   21(2):114. DOI:10.4103/ejop.ejop_72_18.
               cancer[J]. Cell Death Discov,2020,6:112. DOI:10.1038/  [37]HICKSON D A,BURCHFIEL C M,PETRINI M F,et al. Leptin
               s41420-020-00349-0.                                  is inversely associated with lung function in African Americans,
           [24]SARGOLZAEI J,CHAMANI E,KAZEMI T,et al. The role      independent of adiposity:the Jackson Heart Study[J]. Obesity
               of adiponectin and adipolin as anti-inflammatory adipokines in   (Silver  Spring),2011,19(5):1054-1061.  DOI:
               the formation of macrophage foam cells and their association with   10.1038/oby.2010.240.
               cardiovascular diseases[J]. Clin Biochem,2018,54:1-10.   [38]HANSEL N N,GAO L,RAFAELS N M,et al. Leptin receptor
               DOI:10.1016/j.clinbiochem.2018.02.008.               polymorphisms and lung function decline in COPD[J]. Eur Respir J,
           [25]WEI C Y,WANG Y M,HAN L,et al. Nitrate esters alleviated   2009,34(1):103-110. DOI:10.1183/09031936.00120408.
               coronary atherosclerosis through inhibition of NF-κB-regulated   [39]PÉREZ-BAUTISTA O,MONTAÑO M,PÉREZ-PADILLA R,
               macrophage polarization shift in epicardial adipose tissue[J].   et al. Women with COPD by biomass show different serum profile of
               J Cardiovasc Pharmacol,2020,75(5):475-482. DOI:      adipokines,incretins,and peptide hormones than smokers[J].
               10.1097/FJC.0000000000000818.                        Respir Res,2018,19(1):239. DOI:10.1186/s12931-018-
           [26]AJUWON K M,SPURLOCK M E. Adiponectin inhibits LPS-   0943-4.
               induced NF-kappaB activation and IL-6 production and increases   [40]ZHOU L,YUAN C,ZHANG J Y,et al. Circulating leptin
   112   113   114   115   116   117   118   119   120   121   122