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体质指数在焦虑症与抑郁症关系中的调节效应研究

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田洋丽 1，2 ，杨肇熙 ，张剑昭 ，邹晓伟 1，2 ，冯基高 ，朱博 ，万爱兰 1* 扫描二维码
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【摘要】 背景 焦虑症与抑郁症同属精神类疾病，单一焦虑症或抑郁症患者随病情进展会高概率出现“焦虑 - 抑
郁共病”现象，但目前预防两种疾病发展成“共病”及解决二者“共病”的相关研究较少。目的 探讨焦虑症与抑郁
症之间的相关性，以及体质指数（BMI）在二者相关性中的调节效应。方法 采用简单随机抽样法抽取 2021-06-01 至
2021-08-31 南昌大学第一附属医院门诊部和住院部收治的 86 例焦虑症患者为研究对象。采用自编人口学问卷调查患
者一般人口学特征，采用汉密尔顿焦虑量表、汉密尔顿抑郁量表评估患者焦虑症及抑郁症严重程度。焦虑症与抑郁症、
焦虑症与 BMI、抑郁症与 BMI 的相关性分析采用 Pearson 相关分析；采用分层回归分析探究 BMI 在焦虑症与抑郁症中
的调节效应。结果 共 80 例患者符合纳入与排除标准且被同时诊断为抑郁症。患者焦虑症与抑郁症呈正相关（r=0.70，
P<0.01）；BMI 与焦虑症无线性相关（r=0.03，P>0.05）；BMI 与抑郁症无线性相关（r=0.14，P>0.05）；BMI 调节了
焦虑症与抑郁症之间的相关性（β=-0.16，P<0.01）。结论 BMI 可以减弱焦虑症对抑郁症的影响，有助于预防二者
发展成共病性精神障碍，为未来制定新的饮食标准或运动模式进行心理健康预防和治疗提供新思路，在一定程度上拓
展营养精神病学的研究领域。
【关键词】 焦虑症；抑郁症；人体质量指数；数据相关性；调节效应
【中图分类号】 R 749.72 【文献标识码】 A DOI：10.12114/j. issn.1007-9572.2021.01.416
田洋丽，杨肇熙，张剑昭，等 . 体质指数在焦虑症与抑郁症关系中的调节效应研究［J］. 中国全科医学，2022，25
（11）：1368-1372. ［www. chinagp. net］
TIAN Y L，YANG Z X，ZHANG J Z，et al. Study on the moderating effect of body mass index in correlation of anxiety and
depression disorders［J］. Chinese General Practice，2022，25（11）：1368-1372.

Study on the Moderating Effect of Body Mass Index in Correlation of Anxiety and Depression Disorders TIAN Yangli 1，
2 3 1 1，2 1 1 1*
，YANG Zhaoxi ，ZHANG Jianzhao ，ZOU Xiaowei ，FENG Jigao ，ZHU Bo ，WAN Ailan
1.Department of Psychosomatic Medicine，the First Affiliated Hospital of Nanchang University，Nanchang 330006，China；
2.School of Public Administration，Nanchang University，Nanchang 330031，China
3.Department of Child Healthcare，Maternal and Child Health Hospital of Shenzhen Guangming District，Shenzhen 518107，
China
*
Corresponding author：WAN Ailan，Chief physician，Professor；E-mail：903594921@qq.com
【Abstract】 Background As two different kinds of mental disorders，anxiety disorder and depressive disorder
could probably coexist in one with the proceeding of the illness. However，there are few studies on how to prevent and treat
the coexistence of anxiety and depressive disorders. Objective To discuss the relationship between anxiety and depressive
disorders，and the moderating effect of body mass index（BMI）in their relationship. Methods By use of simple random
sampling，86 outpatients and inpatients with anxiety disorders were selected from the First Affiliated Hospital of Nanchang
University during June 1st to August，31st，2021. A self-made demographic questionnaire was used to obtain the demographic
information. The Hamilton Anxiety Rating Scale was used to assess the anxiety level. The Hamilton Rating Scale for Depression
was used to assess the depression level. Pearson correlation analyses were performed to assess the relationship between anxiety and
depression disorders，and that between BMI and anxiety or depression disorder. Hierarchical regression analysis was adopted to
explore the moderating effect of BMI on the relationship between anxiety and depressive disorders. Results Eighty eligible cases
were also diagnosed with depression. The anxiety prevalence was significantly increased with depression prevalence（r=0.70，
P<0.01）. BMI had no significant linear correlation with anxiety prevalence（r=0.03，P>0.05）. BMI also had no significant

基金项目：江西省学位与研究生教育教学改革研究项目（JXYJG-2019-033）
1.330006 江西省南昌市，南昌大学第一附属医院心身医学科 2.330031 江西省南昌市，南昌大学公共管理学院 3.518107 广东
省深圳市光明区妇幼保健院儿童保健科
*
通信作者：万爱兰，主任医师，教授；E-mail：903594921@qq.com
本文数字出版日期：2022-03-18