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Inventory was used to assess the dyadic coping under stress. The Chinese version of the Lock-Wallace Marriage (Love)
Relationship Adjustment Scale was used to evaluate the quality of intimate relationships between couples,the The Chinese version
of the World Health Organization Quality of Life-BREF Scale (including the four dimensions of physical health,mental health,
social relations,and environment) was used to examine the quality of life of patients. Results A total of 320 questionnaires
were distributed,11 invalid questionnaires were excluded,and 309 valid questionnaires were returned,with an effective
recovery rate of 96.56%. The average score of positive dyadic coping,negative dyadic coping and total score of dyadic coping for
309 patients were (48.2±7.4),(8.3±1.4),and (97.9±11.4),respectively. The Chinese version of Locke-Wallace
Marital (love) Adjustment and Prediction Test's mean score was (90.9±19.7). The average score for the physical domain,
psychological domain,social domain,and environment domain were(41.9±14.1),(49.8±11.9),(50.6±13.4),
and(47.8±9.9),respectively. Multiple linear regression analysis showed that the total score of the Lock-Wallace Marital
(love) Adjustment and Prediction Scale were significantly correlated with physical domain scores in gynecologic cancer patients
(P<0.05); The Lock-Wallace Marital (love) Adjustment and Prediction Scale scores were associated with psychological
domain scores in gynecologic cancer patients (P<0.05);The Lock-Wallace Marital (love) Adjustment and Prediction Scale
scores were associated with social domain scores in gynecologic cancer patients (P<0.05);The total score of dyadic coping and
Lock-Wallace Marital (love) Adjustment and Prediction Scale were significantly correlated with environment domain scores
in gynecologic cancer patients (P<0.05). The results of Structural Equation Model showed that the total score of dyadic coping
positively predicted Lock-Wallace Marital (love) Adjustment and Prediction Scale(β=0.931,P<0.001),Lock-Wallace
Marital (love) Adjustment and Prediction Scale scores positively predicted the World Health Organization Quality of Life-BREF
Scale scores (β=0.781,P=0.012),and the total score of dyadic coping exerted no predictive effect on the World Health
Organization Quality of Life-BREF questionnaire scores(β=0.112,P=0.688).The results of the bootstrap sampling method
(5 000 replicates) showed that the mediating effect of intimate relationship on the relationship between dyadic coping and
quality of life was 0.727,accounting for 86.7% of the total effect. Conclusion Gynecological cancer patients may have a
relatively low level of dyadic coping,unsatisfactory intimate relationship,and poorer quality of life. The dyadic coping can
indirectly predict the quality of life through intimate relationship was verified by structural equation modeling.
【Key words】 Genital neoplasms,female;Gynecological cancer;Intimate relationship;Dyadic coping;Quality of
life;Mediating effect
妇科癌症是全世界女性常见的一类恶性肿瘤,在我
本研究背景:
国约占所有新发癌症的 5% [1] ,具有高发病率、高死亡
由于妇科癌症的诊断、治疗和康复涉及生殖系统
率及年轻化趋势 [2-3] 。然而,由于疾病发生于生殖系统
特殊部位,女性患者在面对子宫、卵巢等生殖器官
特殊部位,疾病的诊断、治疗和康复过程所致的绝经、
受到损害或缺如、绝经期或更年期提前、荷尔蒙改变、
更年期症状、性功能障碍等问题 [4] ,以及疾病所致夫
性功能障碍等问题时,会额外高度关注女性特征变
妻角色和亲密关系的调适,使患者承受巨大的生理、心
化和性功能改变,产生较严重的负性情绪,影响夫妻
理及社会压力 [5] 。受女性生殖系统癌症的影响,妇科
支持应对方式,破坏夫妻亲密关系,促使生理、心理、
癌症患者会额外关注身体变化和性功能改变,病耻感严
社会等各个方面的生活质量下降。
重,因此亲密关系问题较其他癌症群体更为突出 [6] 。
同时,患者配偶不仅为患者提供情感、经济、症状管理 支持应对与亲密关系、生活质量密切相关,亲密关系是
等支持,还面临患者因治疗导致的女性生殖器官损害或 影响生活质量的重要因素。然而目前针对夫妻支持应对
缺如而承担一定的压力,对夫妻间的沟通和亲密关系造 和亲密关系协同促进癌症患者生活质量的研究较少,夫
成了极大的负面影响,甚至可能导致离婚 [7] ,不利于 妻亲密关系对妇科癌症患者夫妻支持应对与生活质量的
患者的康复。有研究显示,令人满意的亲密关系是疾病 调节作用机制尚未明确。因此,本研究旨在探究妇科癌
转归的重要预测因素,夫妻支持应对可能是维持亲密关 症患者夫妻支持应对、亲密关系对生活质量的作用路径
系及重建个人、双方身心健康的重要手段 [8] 。夫妻支 及程度,揭示亲密关系对妇科癌症患者生活质量的影响
持应对是指伴侣双方在面对共同压力事件时的共同反应 机制,尝试从新的角度为该群体构建有针对性的干预方
和决策 [9] 。妇科癌症作为夫妻共同压力事件,丈夫与 案提供依据。
妻子的夫妻支持应对行为是其他关系无法替代的。既往 1 对象与方法
针对其他癌症 [10] 或慢性病群体 [11] 的研究表明,夫妻 1.1 研究对象 采用便利抽样法,选取 2020 年 5 月至