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·990· http://www.chinagp.net E-mail:zgqkyx@chinagp.net.cn
·流行病学研究·
2005—2016 年中国女性卵巢癌发病及死亡趋势研究
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黄海涛 ,陈姝玉 ,耿旭 ,万晓 ,贾瑞英 ,梁丹丹 ,陈超然 1* 扫描二维码
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【摘要】 背景 卵巢癌对女性健康的危害已得到全世界的广泛关注,但目前缺乏针对我国卵巢癌发病及死亡趋
势分析的研究。目的 通过收集《中国肿瘤登记年报》中 2005—2016 年卵巢癌发病与死亡数据,描述和分析该时期
我国女性卵巢癌发病与死亡变化趋势,为我国卵巢癌的科学防控提供参考依据。方法 整理 2005—2016 年卵巢癌发
病与死亡数据,计算每年的标化发病率、标化死亡率、年龄别发病率和年龄别死亡率。运用 Joinpoint 软件计算年度变
化百分比(APC)和平均年度变化百分比(AAPC),分析我国卵巢癌发病与死亡随时间(年度)的变化趋势。结果
2005—2016 年我国卵巢癌发病率整体呈快速上升趋势(AAPC=7.25%,P<0.05),历年城市的卵巢癌标化发病率均高
于农村,35~ 岁年龄组以后发病率随年龄增长呈上升趋势,发病高峰主要集中出现在 55~ 岁年龄组。2005—2016 年我
国卵巢癌死亡率整体呈快速上升趋势(AAPC=6.06%,P<0.05),历年城市卵巢癌标化死亡率均高于农村,35~ 岁年龄
组以后死亡率随年龄的增长快速上升,75~ 岁年龄组以后死亡率逐渐下降。结论 2005—2016 年我国卵巢癌发病率和
死亡率呈快速上升趋势,但在年龄和城乡之间表现出一定差异,应采取针对性措施,积极制订卵巢癌防治策略,降低
卵巢癌的危害。
【关键词】 卵巢肿瘤;发病率;死亡率;流行病学研究特征;Joinpoint 回归分析
【中图分类号】 R 737.31 【文献标识码】 A DOI:10.12114/j.issn.1007-9572.2021.01.606
黄海涛,陈姝玉,耿旭,等 . 2005—2016 年中国女性卵巢癌发病及死亡趋势研究[J]. 中国全科医学,2022,25
(8):990-994. [www.chinagp.net]
HUANG H T,CHEN S Y,GENG X,et al. Ovarian cancer in China:trends in incidence and mortality,2005—
2016[J]. Chinese General Practice,2022,25(8):990-994.
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Ovarian Cancer in China:Trends in Incidence and Mortality,2005—2016 HUANG Haitao ,CHEN Shuyu ,GENG
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Xu ,WAN Xiao ,JIA Ruiying ,LIANG Dandan ,CHEN Chaoran 1*
1.School of Nursing and Health,Henan University,Kaifeng 475004,China
2.School of Aviation Engineering,Xinyang Aviation Vocational College,Xinyang 475000,China
3.Henan Medical School,Henan University,Kaifeng 475004,China
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Corresponding author:CHEN Chaoran,Professor;E-mail:kfccr@126.com
【Abstract】 Background The health impairment caused by ovarian cancer in female population has become a global
focus. However,there is a lack of research on ovarian cancer incidence and mortality trends in Chinese female population.
Objective To describe the trends of ovarian cancer incidence and mortality in China from 2005 to 2016 by analyzing the
incidence and death data of ovarian cancer collected from Chinese Cancer Registry Annual Report,providing a basis for the
scientific prevention and control of ovarian cancer in China. Methods The incidence and mortality of ovarian cancer in China
during 2005 to 2016 were collected and input into Excel spreadsheets,then the annual age-standardized incidence rate,age-
standardized mortality rate,age-specific incidence rate and age-specific mortality rate were computed. Joinpoint Regression
Program was used to estimate the annual percentage change(APC),and average annual percentage change(AAPC) to
analyze the temporal trends of annual ovarian cancer incidence and mortality rates. Results The incidence rate of ovarian cancer
showed a trend of rapid increase over the period of 2005 to 2016(AAPC=7.25%,P<0.05). The annual age-standardized ovarian
cancer incidence rate in urban areas was higher than that in rural areas in each year. The ovarian cancer incidence rate increased
obviously with age in women over the age of 35,and peaked in those aged 55 years old. From 2005 to 2016,the overall ovarian
cancer mortality rate showed a rapid upward trend(AAPC=6.06%,P<0.05). The age-standardized ovarian cancer mortality rate
基金项目:河南省社科规划决策咨询项目(2018JC38);河南大学研究生教育创新与质量提升计划项目(SYL19060141);河
南省研究生教育改革与质量提升工程项目(YJS2021AL074)
1.475004 河南省开封市,河南大学护理与健康研究所 2.475000 河南省信阳市,信阳航空职业学院航空工程学院 3.475004 河
南省开封市,河南大学医学院
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通信作者:陈超然,教授;E-mail:kfccr@126.com
本文数字出版日期:2022-01-28