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               role for CXCR2[J]. J Leukoc Biol,2004,76(2):441-450.   [45]SONG D,LIU F,ZHU B,et al. Global Immunometabolic profiling
               DOI:10.1189/jlb.1003495.                             of AECOPD[J]. Small Methods,2020,4(12):2000483.
           [31]RAHMAN I,ADCOCK I M. Oxidative stress and redox regulation of   DOI:10.1002/smtd.202000483.
               lung inflammation in COPD[J]. Eur Respir J,2006,28(1):  [46]ROOS  A  B,SETHI  S,NIKOTA  J,et  al.  IL-17A  and  the
               219-242. DOI:10.1183/09031936.06.00053805.           promotion of neutrophilia in acute exacerbation of chronic obstructive
           [32]AGUSTI A,EDWARDS L D,RENNARD S I,et al. Persistent   pulmonary disease[J]. Am J Respir Crit Care Med,2015,
               systemic inflammation is associated with poor clinical outcomes in   192(4):428-437. DOI:10.1164/rccm.201409-1689OC.
               COPD:a novel phenotype[J]. PLoS One,2012,7(5):  [47]YANG  X,HUO  B,ZHONG  X,et  al.  Imbalance  between
               e37483. DOI:10.1371/journal.pone.0037483.            subpopulations  of  regulatory  T  cells  in  patients  with  acute
           [33]VANFLETEREN L E G W,SPRUIT M A,GROENEN M,et al.      exacerbation of COPD[J]. COPD,2017,14(6):618-625.
               Clusters of comorbidities based on validated objective measurements   DOI:10.1080/15412555.2017.1385055.
               and systemic inflammation in patients with chronic obstructive   [48]王菲菲 . 肺部感染对急性加重期慢性阻塞性肺疾病患者免疫功
               pulmonary disease[J]. Am J Respir Crit Care Med,2013,187(7):  能的影响[J]. 中国现代医药杂志,2019,21(12):74-76.
               728-735. DOI:10.1164/rccm.201209-1665OC.             DOI:10.3969/j.issn.1672-9463.2019.12.019.
           [34]WOUTERS E F M. Local and systemic inflammation in chronic   [49]GUO-PARKE H,LINDEN D,WELDON S,et al. Mechanisms
               obstructive pulmonary disease[J]. Proc Am Thorac Soc,2005,  of virus-induced airway immunity dysfunction in the pathogenesis
               2(1):26-33. DOI:10.1513/pats.200408-039MS.           of COPD disease,progression,and exacerbation[J]. Front
           [35]YOUSUF A,IBRAHIM W,GREENING N J,et al. T2 biologics   Immunol,2020,11:1205. DOI:10.3389/fimmu.2020.01205.
               for chronic obstructive pulmonary disease[J]. J Allergy Clin   [50]MCKENDRY  R  T,SPALLUTO  C  M,BURKE  H,et  al.
               Immunol Pract,2019,7(5):1405-1416. DOI:10.1016/j.    Dysregulation of antiviral function of CD 8 (+)T cells in the chronic
               jaip.2019.01.036.                                    obstructive pulmonary disease lung. Role of the PD-1-PD-L1
           [36]HSU A T,GOTTSCHALK T A,TSANTIKOS E,et al. The role   axis[J]. Am J Respir Crit Care Med,2016,193(6):642-
               of innate lymphoid cells in chronic respiratory diseases[J]. Front   651. DOI:10.1164/rccm.201504-0782OC.
               Immunol,2021,12:733324. DOI:10.3389/fimmu.2021.733324.  [51]GRUNDY S,PLUMB J,LEA S,et al. Down regulation of T
           [37]RABE K F,WATZ H. Chronic obstructive pulmonary disease[J].   cell receptor expression in COPD pulmonary CD 8  cells[J].
               Lancet,2017,389(10082):1931-1940. DOI:10.1016/       PLoS One,2013,8(8):e71629. DOI:10.1371/journal.
               S0140-6736(17)31222-9.                               pone.0071629.
           [38]DONOVAN T,MILAN S J,WANG R,et al. Anti-IL-5 therapies   [52]YERKOVICH  S  T,HALES  B  J,CARROLL  M  L,et  al.
               for chronic obstructive pulmonary disease[J]. Cochrane Database Syst   Reduced rhinovirus-specific antibodies are associated with acute
               Rev,2020,12(12):CD013432. DOI:10.1002/14651858.      exacerbations of chronic obstructive pulmonary disease requiring
               CD013432.pub2.                                       hospitalization[J]. BMC Pulm Med,2012,12:37. DOI:
           [39]SIVAPALAN P,BIKOV A,JENSEN J U. Using blood eosinophil   10.1186/1471-2466-12-37.
               count as a biomarker to guide corticosteroid treatment for chronic   [53]STEURER-STEY C,BACHMANN L M,STEURER J,et al.
               obstructive pulmonary disease[J]. Diagnostics(Basel),  Oral purified bacterial extracts in chronic bronchitis and COPD:
               2021,11(2):236. DOI:10.3390/diagnostics11020236.     systematic review[J]. Chest,2004,126(5):1645-1655.
           [40]ROSELL  A,MONSÓ  E,SOLER  N,et  al.  Microbiologic   DOI:10.1378/chest.126.5.1645.
               determinants of exacerbation in chronic obstructive pulmonary   [54]BRAIDO F,TARANTINI F,GHIGLIONE V,et al. Bacterial
               disease[J]. Arch Intern Med,2005,165(8):891-897.     lysate in the prevention of acute exacerbation of COPD and in
               DOI:10.1001/archinte.165.8.891.                      respiratory recurrent infections[J]. Int J Chron Obstruct Pulmon
           [41]SOLER N,EWIG S,TORRES A,et al. Airway inflammation   Dis,2007,2(3):335-345.
               and bronchial microbial patterns in patients with stable chronic   [55]徐鹏,张骅,陈星华 . 细菌溶解产物对慢性阻塞性肺疾病稳定
               obstructive pulmonary disease[J]. Eur Respir J,1999,14(5):  期患者免疫功能影响[J]. 中华实用诊断与治疗杂志,2010,
               1015-1022. DOI:10.1183/09031936.99.14510159.         24(11):1117-1118.
           [42]SETHI S,MALONEY J,GROVE L,et al. Airway inflammation   [56]华颖坚,刘景桢 . 卡介菌多糖核酸联合抗组胺药序贯疗法治疗
               and bronchial bacterial colonization in chronic obstructive pulmonary   慢性荨麻疹疗效观察[J]. 皮肤病与性病,2018,40(4):
               disease[J]. Am J Respir Crit Care Med,2006,173(9):   564-566. DOI:10.3969/j.issn.1002-1310.2018.04.060.
               991-998. DOI:10.1164/rccm.200509-1525OC.        [57]冯思芳,陈天君,阳甜,等 . 卡介菌多糖核酸对慢性阻塞性肺
           [43]KO F W,CHAN K P,HUI D S,et al. Acute exacerbation of   疾病患者炎症因子水平及免疫功能的影响[J]. 现代生物医
               COPD[J]. Respirology,2016,21(7):1152-1165. DOI:      学 进 展,2017,17(15):2873-2876. DOI:10.13241/j.cnki.
               10.1111/resp.12780.                                  pmb.2017.15.018.
           [44]SETHI S,MURPHY T F. Infection in the pathogenesis and course of   FENG S F,CHEN T J,YANG T,et al. Effect of bacillus
               chronic obstructive pulmonary disease[J]. N Engl J Med,2008,  calmette-guerin polysaccharide nucleic acid on the inflammatory
               359(22):2355-2365. DOI:10.1056/NEJMra0800353.        factors and immune functions of patients with chronic obstructive
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