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Cancers were classified by the Guideline for Chinese Cancer Registration and International Classification of Disease for Oncology,
Third Edition(ICD-O). Sex-specific and age-specific crude incidence rates,standardized incidence rates,and cumulative
incidence rates(0-74 years),as well as truncated age-standardized incidence rate(35-64 years) were calculated. The
standardized incidence rate was calculated by the 2000 Population Census of China and Segi's world population structure(Chinese
age-standardized incidence rate was referred to as ASIRC,and world age-standardized incidence rate as ASIRW). Results
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There were 4 205 registered new cases of cancer from 2016 to 2020 in Cenxi. The crude cancer incidence rate was 98.77/10 .
The ASIRC,ASIRW,cumulative incidence rate(0-74 years) and the truncated age-standardized incidence rate(35-64
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years) were 85.48/10 ,82.54/10 ,9.08%,and 165.08/10 ,respectively. The male crude incidence rate was higher than that
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in female(χ =161.703,P<0.001). The crude cancer incidence rates for 0-34 year-old overall population,males and females
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were all under 34.00/10 ,for 35-39 year-old overall population,males and females were 64.02/10 ,83.94/10 ,43.75/10 ,
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respectively,and for 75-79 year-old were 437.83/10 ,597.17/10 ,292.76/10 ,respectively,reaching the highest incidence
rate. The top three cancers in terms of crude incidence rate for the overall population were liver cancer(23.47%),lung cancer
(17.53%),and nasopharynx cancer(10.70%),for males were liver cancer(30.94%),lung cancer(20.84%),and
nasopharynx cancer(12.51%),while for females were breast cancer(16.44%),lung cancer(12.12%),and liver cancer(11.31%).
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Conclusion Compared to the Chinese average(ASIRC and ASIRW were 190.64/10 ,204.8/10 ),and world average(ASIRW
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were 201.0/10 ) from 2016 to 2020,Cenxi had lower overall standardized cancer incidence rates (ASIRC and ASIRW were
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85.48/10 ,82.54/10 ) . The crude cancer incidence rate in males was higher than that of females. The crude cancer incidence
rate reached its peak at the age range of 75-79 years for the overall population,males or females. The top three cancers in terms of
crude incidence in the overall population were liver cancer,lung cancer and nasopharynx cancer.
【Key words】 Neoplasms;Incidence;Liver neoplasms;Stomach neoplasms;Epidemiologic measurements;
Cenxi;GuangxXi
2020 年世界卫生组织发布的全球新发癌症病例调 年龄别粗发病率、标准化发病率、累积发病率(恶性肿
查显示,预计 2040 年全世界癌症负担比 2020 年增长 瘤一般计算 0~74 岁的累计发病率)、截缩发病率(恶
46% [1] 。恶性肿瘤一直是全球医疗卫生关注的焦点。 性肿瘤一般截取 35~64 岁易发年龄段,其标准人口构成
随着经济与科技的高速发展,生活质量的提高,预期人 为 Segi's 世界人口)及构成比。人口标准化发病率计算
类寿命延长与人口老龄化进程加剧将成为中国乃至世界 采用 2000 年中国标准人口构成(中国标准化发病率以
恶性肿瘤高发的重要因素之一 [2] 。岑溪市位于广西东 下简称中标率)和 Segi's 世界人口结构计算(世界标准
南部,属丘陵山区,市境处于北纬 22° 37'~23° 13', 化发病率以下简称世标率)。计算公式如下:(1)粗
东经 110° 43'~111° 22',东、南界与广东接壤,是大 发病率 = 某特定时期内某人群中某病新发病例数 / 同期
西南与珠三角经济圈的结合部;水资源符合国家标准界 该人群暴露人口数 ×100 000;(2)某年龄组粗发病率
限指标的三种类型:偏硅酸型、碳酸型、蒸馏水型,属 = 某年龄组发病人数 / 同年龄组人口数 ×100 000;(3)
中国长寿乡之一 [3] ,市辖 14 个乡镇:岑城镇、安平镇、 标准化发病率 =〔∑(标准人口年龄构成 × 年龄别发
波塘镇、诚谏镇、大隆镇、大业镇、归义镇、筋竹镇、 病率)〕/(∑标准人口年龄构成)×100 000;(4)累
梨木镇、马路镇、南渡镇、糯垌镇、三堡镇和水汶镇。 积发病率 = ∑(年龄组发病率 × 年龄组距)×100%;
2016—2020 年的常住人口总人数为 4 257 423 人,其中 (5)截缩发病率 =(∑截缩段各年龄组发病率 × 各段
男 2 220 632 人、女 2 036 791 人。本研究通过收集和统 标准年龄构成)/(∑各段标准年龄构成)×100 000;(6)
计分析岑溪市 2016—2020 年恶性肿瘤发病数据,与全 某恶性肿瘤构成比 = 某恶性肿瘤发病人数 / 总发病人数
国及世界的恶性肿瘤发病率进行对比分析,现报道如下。 ×100%。
1 资料与方法 1.3 统计学方法 应用 SPSS 23.0 统计学软件和
1.1 资料来源 2016—2020 年岑溪市恶性肿瘤发病资 Gradgraph 8.0 软件对以上数据进行统计分析。计数资料
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料来源于岑溪市疾病预防控制中心肿瘤登记数据,人口 以相对数描述,组间比较采用 χ 检验。以 P<0.05 为
资料来源于岑溪市公安局。数据导出系统时存在重复数 差异有统计学意义。
据,由人工审查、记录并进行删除。 2 结果
1.2 观察指标及计算方法 依据《中国肿瘤登记指导 2.1 岑溪市总体恶性肿瘤发病情况 2016—2020 年岑
手册》和《国际疾病分类肿瘤学专辑》(ICD-O)第 3 溪市共新发恶性肿瘤 4 205 例(去除系统中个别未知性
版对恶性肿瘤进行编码分类 [4-5] 。统计指标包括性别和 别病例与重复病例),其中男性发病人数 2 605 例,