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    05 June 2025, Volume 28 Issue 16
    Guidelines·Consensus
    Interpretation of Global Strategy for the Diagnosis, Treatment, Management and Prevention of Chronic Obstructive Pulmonary Disease 2025 Report
    CHEN Dian, LONG Huanyu, ZHANG Congxi, CHU Lanhe, LI Shurun, CHEN Yahong
    2025, 28(16):  1937-1949.  DOI: 10.12114/j.issn.1007-9572.2024.0588
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    The global initiative for chronic obstructive lung disease (GOLD) 2025 report, released on November 11th, 2024, marks the second update since GOLD 2023. Overall, this version maintains similar definition, diagnosis, assessment, and treatment for COPD as in GOLD 2024, but with revisions and expansions in 12 specific areas. These include: added explanations and references on lung function trajectories, expanded content on dysbiosis, updates and additions to spirometry, revised cardiovascular risk information for COPD patients, updated guidance on CT imaging for COPD, new insights into the impact of climate change on COPD, updated vaccination recommendations, updated follow-up pharmacological treatments, new guidance for delivery of pulmonary rehabilitation, revised recommendations on ICS withdrawal in patients on LABA+ICS therapy, updated information on PDE3 and PDE4 inhibitors and other exacerbation-reducing medications, and additional content on pulmonary hypertension. The article introduces and interprets the new contents.

    Special Research Report
    The Necessity and Path Exploration of Developing Psychosis Subspecialty among General Practitioners in Primary Care Settings
    YE Qing, CHEN Mingmin, REN Jingjing
    2025, 28(16):  1950-1954.  DOI: 10.12114/j.issn.1007-9572.2023.0891
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    General practitioners with sub-specialties can not only provide high-quality general medical services, but also provide a certain depth of specialized medical services. The combination of general practitioners with sub-specialties of different specialties can provide relatively comprehensive and certain depth of basic medical services for residents in their jurisdictions. Under the situation that the professional service capacity of mental health cannot meet the needs of residents, the necessity of encouraging some general practitioners to develop mental health subspecialties has become increasingly prominent. This article analyzes the necessity of training general practitioners with psychosis subspecialty, the advantages of developing psychosis subspecialty among general practitioners, the obstacles to promoting the development of psychosis sub-expertise of general practitioners in primary care are proposed: the construction of general practitioners training bases for psychosis sub-expertise, the learning platform for general practitioners with psychosis sub-expertise was expanded, construction of sub-specialty teachers of psychosis, policy and financial support, salary and promotion incentive policies, etc., are expected to help general practitioners develop psychosis sub-expertise.

    Diagnosis and Comprehensive Management of Rare Diseases: the Indispensable Role of General Practitioners
    GU Jie, HUANG Yanyan
    2025, 28(16):  1955-1960.  DOI: 10.12114/j.issn.1007-9572.2023.0925
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    Rare diseases, characterized by low prevalence and significant challenges in diagnosis and management, have increasingly gained attention in recent years due to advancements in medical technology. As gatekeepers of health and managers of patient and family health, general practitioners in many countries are now being integrated into the framework for managing rare diseases. The article discusses the current status of general practitioners in the diagnosis and management of rare diseases, including their role in the management process, efforts made, and the lack of knowledge about rare diseases. It highlights that despite challenges in recognizing rare diseases, most general practitioners are willing to improve their awareness and training. They can effectively participate in the comprehensive management of patients with rare diseases, playing a vital role in early identification, coordinating treatment, and providing integrated services.

    Chinese General Practice/Primary Care Services
    The Impact of Interaction Network within Family Physician Team on Job Satisfaction in Central China
    CHEN Yixiang, TANG Shangfeng
    2025, 28(16):  1961-1965.  DOI: 10.12114/j.issn.1007-9572.2024.0176
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    Background

    Family physician-contracted service is an important way to change the mode of primary health care, and it is also the key and breakthrough to realize tiered diagnosis and treatment. How to strengthen the construction of family physician team and thus improve job satisfaction has become an urgent problem.

    Objective

    To explore the relationship between the network structural characteristics within family physician team and job satisfaction at the team level, and to provide a reference for strengthening the construction of family physician team.

    Methods

    From October 2021 to December 2023, we combined convenience sampling and cluster sampling to conduct field research on family physician teams in Qianjiang, Hubei, Changsha, Hunan and Nanyang, Henan. The Family Physician Team Members' Basic Information Questionnaire, the Family Physician Team Interaction Network Questionnaire and the Family Physician Team Job Satisfaction Scale were used to collect data. We used hierarchical linear regression analysis to verify the impact of the network density and centralization within family physician team on job satisfaction.

    Results

    The transition processes of family physician team showed obvious network structure characteristics of low density (0.29±0.11) and high centralization (0.88±0.19). The average job satisfaction score of family physician team was (20.30±2.42), which was moderately high. The results of the hierarchical linear regression analysis showed that the centralization of transition processes positively affected job satisfaction (β=0.576, t=7.091, P<0.001) ; the density of transition processes positively affected job satisfaction (β=0.228, t=2.478, P<0.05) ; the density of action processes positively affected job satisfaction (β=0.324, t=2.624, P<0.05) ; the density of interpersonal processes positively affected job satisfaction (β=0.368, t=3.549, P<0.001) .

    Conclusion

    There is room for optimizing the network structural characteristics within family physician team in Central China. The network density and centralization of family physician teams have positive effects on job satisfaction. It is recommended to improve the internal collaboration mechanism and optimize the centralized network structure within family physician team.

    Degree of Family Doctor Teamwork and Influencing Factors under the Program of Integration of Medical and Preventive Care
    FAN Wenyu, MA Xingli, ZHANG Shilong, ZHANG Xindan, ZHAO Yang, WANG Haipeng
    2025, 28(16):  1966-1972.  DOI: 10.12114/j.issn.1007-9572.2024.0390
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    Background

    As the aging of the population intensifies and the burden of non-communicable diseases continues to rise, traditional health service models have become insufficient to meet people's health needs. Therefore, promoting the integration of medical and preventive care has become crucial for improving residents' health levels. Family doctor teams, as the main implementers of these integrated care, play a pivotal role. However, the current lack of effective multidisciplinary collaboration among family doctor teams has severely hindered the effective implementation and provision of integrated medical and preventive care.

    Objective

    To investigate the teamwork of family doctors in the integration of medical and preventive care in Shandong Province, explore its influencing factors, so as to provide a reference for further improving the contract service of family doctors and the integration of medical and preventive care.

    Methods

    In August 2023, a multi-stage stratified random sampling method was employed, selecting Yantai City, Weifang City, and Liaocheng City from the eastern, central, and western regions of Shandong Province, taking into account geographical location and economic development levels. Within each city, one district and one county city were randomly selected as sample areas, resulting in a survey of 481 family doctors. Based on extensive searches of relevant domestic and international literature and consultations with experts, a specialized questionnaire for primary care doctors was designed for the survey. This questionnaire encompassed three key sections: a general information survey, an assessment of the provision of integrated medical and preventive care services, and an evaluation of the collaboration levels among family doctor teams within these services. Questionnaires were used to investigate the implementation of integrated medical and preventive care and the collaboration among family doctors within these services. Binary Logistic regression analysis was employed to examine the factors influencing the collaboration among family doctors in integrated medical and preventive care.

    Results

    76.1% (366/481) of family doctors exhibited a high level of teamwork in the integration of medical and preventive care. The results showed that family doctors with bachelor's degree or above (OR=2.343), professional titles of primary (OR=1.887) and intermediate and above (OR=2.978), understanding of the integration of medical and prevention system (OR=6.618), believe that the institution attaching importance to integration of medical and preventive care (OR=2.861), and participating in one (OR=2.561) and two or more trainings within half a year (OR=3.833) had a higher level of teamwork in integration of medical and preventive care (P<0.05) .

    Conclusion

    At this stage, there is still a lot of room for improvement in the teamwork level of family doctors in the integration of medical and preventive care. It is necessary to continue to improve the awareness of family doctors on the integration of medical and preventive care, improve the system of providing institutional medical and prevention integration services, provide reasonable economic subsidies and policy incentives for family doctors, strengthen training, and further improve the level of teamwork of family doctors.

    Study on the Configuration and Action Paths of Factors Affecting the Performance of Primary Healthcare Service
    SHEN Xianlei, HE Rongxin, LIANG Wannian
    2025, 28(16):  1973-1979.  DOI: 10.12114/j.issn.1007-9572.2024.0130
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    Background

    At present, the unbalanced and inadequate development of primary healthcare services does not meet people's growing demand for them in the new era. Identifying the influencing factors and their action paths on the performance of primary healthcare services has always been an issue of common concern in the academic circles.

    Objective

    To clarify the combination of multiple factors and their action paths that affect the performance of primary healthcare services in China, and to provide decision-making basis for further improvement of primary healthcare services.

    Methods

    The study was conducted from November 2022 to August 2023, and the data were obtained from the 2021 China Health Statistics Yearbook and the 2021 China Statistical Yearbook. A fuzzy set qualitative comparative analysis (fsQCA) was conducted with the performance of primary healthcare services in 31 provinces (autonomous regions and municipalities) as the outcome variables, and application of big data, medical technology, government attention, system integration, medical resources and health demand as the conditional variables.

    Results

    The quality of performance of primary healthcare services is the result of a combination of various factors. The results of configuration analysis show that there are 4 configurations to improve the performance of primary healthcare services, which can be classified into 3 patterns: "technology-environment" "organization-environment" and "technology-organization-environment". Configuration 1: Application of Big Data * - Medical Technology * - Government Attention * - System Integration * Medical Resources. Configuration 2: -Application of Big Data * - Medical Technology * System Integration * Medical Resources * - Health Demand. Configuration 3: Application of Big Data * Medical Technology * System Integration * Medical Resources * Health Demand. Configuration 4: Application of Big data * - Government Attention * System Integration * Medical Resources * Health Demand. (* means "and", - means "non"). The consistency of the four configuration solutions was 0.926, the coverage of the solution was 0.612, the original coverage ranged from 0.314 to 0.396, and the unique coverage was from 0.017 to 0.083. The configurations that improve the performance of primary healthcare services are different in eastern, central and western regions of China.

    Conclusion

    At present, increasing the investment of medical resources at the grass-roots level is still a universal measure to improve the performance of primary healthcare services in China, but attention should also be paid to effectively combine technological, organizational and environmental (T-O-E) conditions. The action paths of the influencing factors are notably different in the eastern, central and western regions of China. Therefore, regions should choose different action paths based on their own development endowments and conditions, reasonably allocate limited medical resources, improve TOE conditions in a targeted manner, so as to improve the performance of healthcare services and realize the high-quality development of primary healthcare services.

    The Operational Efficiency of Traditional Chinese Medicine Diagnosis and Treatment Services in Primary Medical Institutions in Tianjin Based on DEA and SFA
    LI Jie, DU Yue, SHAO Shen, PAN Dong, ZHANG Yaxin
    2025, 28(16):  1980-1986.  DOI: 10.12114/j.issn.1007-9572.2023.0711
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    Background

    The inheritance, innovation, and development of traditional Chinese medicine have received high attention from the country. However, the development of grassroots traditional Chinese medicine diagnosis and treatment in China is still uneven, and the operational efficiency of traditional Chinese medicine diagnosis and treatment services in different institutions varies greatly.

    Objective

    By analyzing the operation of traditional Chinese medicine diagnosis and treatment services in grassroots medical institutions in Tianjin in 2021, this study provides a reference for the development of traditional Chinese medicine in grassroots medical institutions.

    Methods

    In 2021, a comprehensive survey method was used to collect relevant data from a total of 270 primary healthcare institutions in 16 administrative regions of Tianjin (Dis1-6 being the six districts within the city, Dis7-10 being the four districts around the city, Dis11 being the Binhai New Area, and Dis12-16 being the five districts in the suburbs), and two methods, BCC and CCR models in Data Envelopment Analysis (DEA) and Stochastic Frontier Analysis (SFA), were comprehensively applied to analyze the operational efficiency of traditional Chinese medicine diagnosis and treatment services in institutions from different perspectives. Through literature research, the input indicators of the DEA model were set as the number of traditional Chinese medicine practitioners, the number of traditional Chinese medicine beds, and the number of traditional Chinese medicine diagnosis and treatment equipment; The output indicators were set as traditional Chinese medicine medical income, number of traditional Chinese medicine diagnosis and treatment personnel, number of discharged patients mainly using traditional Chinese medicine, and number of on-site traditional Chinese medicine service personnel. The SFA model was consistent with the indicators set by DEA, except for the addition of total income as an output indicator.

    Results

    The operation of traditional Chinese medicine diagnosis and treatment services in grassroots medical and health institutions in 7 districts was effective, Dis9 DEA was weakly effective, and DEA was ineffective in 8 districts. There were 8 districts with increasing returns to scale, 7 districts with unchanged returns to scale, and Dis3 showing decreasing returns to scale. There were 8 non DEA effective regions, and all 3 input indicators in each region have redundancy. The phenomenon of insufficient income from traditional Chinese medicine and medical services in the output indicators was more serious in each region. The efficiency of Dis1-6 technology in SFA results (0.733-0.838) was within the high efficiency range; Dis7-10 technology efficiency (0.691-0.912), 3 high efficiency zones and 1 medium efficiency zone; Dis11 technology efficiency of 0.885 was in the high efficiency zone; Dis12-16 (0.399-0.849) had 3 high efficiency zones and 2 medium efficiency zones. The DEA results were basically consistent with the SFA results, indicating that the number of traditional Chinese medicine practitioners had a positive impact on operational efficiency.

    Conclusion

    The overall operational efficiency of traditional Chinese medicine diagnosis and treatment services in grassroots medical institutions in various districts of Tianjin is relatively low, but the overall development trend is positive and has regional characteristics. Overall, Dis1-6 is better than Dis7-10, and Dis7-10 is better than Dis11-16. Each district should plan reasonably according to the actual situation, avoid excessive resource input and insufficient output, and especially increase support for Binhai New Area and the five districts in the suburbs.

    Current Situation and Improvement Measures of the Service Capacity of Traditional Chinese Medicine Centers in Grassroots Medical and Health Institutions
    MA Shanjun, YAN Zhenzhe, WANG Yun
    2025, 28(16):  1987-1991.  DOI: 10.12114/j.issn.1007-9572.2023.0601
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    This study provides a review of the current status of service capabilities, strategies for improving service capabilities, and improvement measures of grassroots traditional Chinese medicine clinics in Haizhou District, Lianyungang City. It describes the current work status of grassroots traditional Chinese medicine clinics in the construction of characteristic departments, family doctor contract services, and medical prevention integration. It is found that there are problems in the operation of traditional Chinese medicine clinics, such as uneven resource allocation, non-standard management, insufficient facilities and equipment, and the need to improve service capabilities. A survey and analysis were conducted on the construction of traditional Chinese medicine clinics in 19 grassroots medical and health institutions to identify common and individual problems. Targeted suggestions and improvement st rategies were proposed to enhance the service capabilities of traditional Chinese medicine clinics, form a characteristic of medical prevention integration, and give full play to the functions and roles of grassroots medical care. Residents received high-quality traditional Chinese medicine services in the community.

    Original Research
    Distribution Characteristics and Equilibrium of General Practitioners among Provinces in China
    LIU Zhiyang, LI Hongyan, YANG Chuanghao
    2025, 28(16):  1992-2000.  DOI: 10.12114/j.issn.1007-9572.2023.0800
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    Background

    Under the process of improving the capacity of primary health services, promoting hierarchical diagnosis and treatment, and realising the integration of medicine and prevention, the state has introduced a series of policies to support the cultivation of general practitioners, and to promote the rational distribution of general practitioners' resources. However, at the present stage, the study on the equilibrium of the distribution of general practitioners is still not comprehensive enough, and lacks the attention to both primary health care and disease prevention.

    Objective

    To set up indicators more comprehensively on the basis of previous studies to evaluate the characteristics and equilibrium of the distribution of general practitioners between provinces in China, and to provide theoretical support for the optimal distribution of general practitioner resources.

    Methods

    We collected data from the 2018-2022 China Health Statistics Yearbook, the 2018-2022 China Statistics Yearbook, and the 2021 China Urban Statistics Yearbook from the websites of the National Health Commission, the National Bureau of Statistics, and offline libraries in April 2023, measured interprovincial general practitioner distribution on an absolute level using five indicators: general practitioners per 10 000 population, general practitioners per 10 square kilometres, the general practitioner-inhabitant disposable income ratio, the general practitioner-primary care institution ratio, and the general practitioner-disease prevention institution ratio, combined with descriptive statistics; The GINI coefficient of the five dimensions of population, area, income, primary health care and disease prevention, combined with the Lorenz curve, were used to preliminarily evaluate the provincial relative distribution gap of general practitioners; Further measured the equilibrium of the distribution of the number of general practitioners among provinces by using the five dimensional DAGUM decomposition GINI coefficient, including inter-group GINI coefficient, intra-group GINI coefficient and inter-group GINI coefficient within each region, combined with the analysis of the agglomeration degree of population and area.

    Results

    During 2017 to 2021, the number of general practitioners in China had been growing rapidly. In 2021, the average number of general practitioners per 10 000 population was 2.93, the median was 2.80, and the standard deviation was 0.87; The GINI coefficient of the five-year population dimension was (0.195±0.047), the area dimension was (0.608±0.019), the income dimension was (0.401±0.015), the primary health care dimension was (0.318±0.058), and the disease prevention dimension was (0.393±0.033) ; The annual Lorentz curve of the population dimension deviated slightly from the 45° line, the area dimension and income dimension deviated significantly, and the Lorentz curve of the primary health care dimension and disease prevention dimension deviated moderately; In the result of DAGUM decomposition GINI coefficient, the contribution rate of GINI coefficient between groups was (59.863%±8.785%), the gap between groups was the main reason for the overall gap, and the hypervariable density was (25.959%±10.052%), and the gap within each regional group could not be ignored. Further decomposition results showd that within the region the inter-group GINI coefficient in the area dimension of East China and North China were higher, 0.570 and 0.504, respectively, and the inter-group GINI coefficient of the income dimension in North China was higher, 0.413, and the gap was mainly from Beijing, Tianjin, and Shanghai and the other provinces in the region; The results of agglomeration analysis showd that the values of Qinghai, Henan, Anhui, Guangdong and Jilin provinces were closer to the reasonable value 1, the values of other provinces were different, but they were close to 1 except for Tianjin, Shanxi, Inner Mongolia, Fujian, Hubei, Ningxia and Xinjiang provinces.

    Conclusion

    In absolute terms, the number of general practitioners in China has reached the established development goal. The construction of general practitioners has made remarkable achievements, but the relative number gap between provinces is still large. Although the polarization of agglomeration degree is improving, it still exists. The equilibrium of the distribution of general practitioners needs to be further optimized. We should continue to strengthen the training efforts to promote the growth of the number of general practitioners, At the same time, we should rely on information technology to encourage cross regional assistance and resource sharing.

    Multimorbidity of Hypertension, Diabetes, and Dyslipidemia and Influencing Factors of Family Function among the Elderly
    HUANG Zhijie, MAI Zhihua, WANG Haoxiang, HE Yuming, DENG Qiaoyan, DAI Ranran, ZHOU Zhiheng
    2025, 28(16):  2001-2010.  DOI: 10.12114/j.issn.1007-9572.2024.0173
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    Background

    With the global population aging at an accelerating rate, the rapid growth of the elderly population in China presents a series of health challenges, particularly in the management of chronic conditions such as hypertension, diabetes, and dyslipidemia. Residents of original residential communities, a unique social unit within the urbanization process, experience a higher prevalence of comorbidities related to these conditions. This underscores the urgent need for effective and comprehensive management strategies. Family function plays a critical role in the management of chronic diseases. For patients with the hypertension, diabetes, and dyslipidemia, family support is not only crucial for improving treatment outcomes but also a key factor in enhancing overall quality of life.

    Objective

    This study aims to investigate the prevalence of comorbidities and family function among older people of original residential communities of Guangzhou with hypertension, diabetes, and dyslipidemia.

    Methods

    The survey was based on the annual health examination services for patients with hypertension and type 2 diabetes, in accordance with the National Basic Public Health Service Standards (Third Edition). Stratified random sampling was used to conduct a questionnaire survey with the APGAR scale among patients of comorbidities of hypertension, diabetes, and dyslipidemia over 60 years old in Panyu District, Guangzhou, between January and June 2023. To explore the multimorbidity and family functioning status of original residential communities of Guangzhou and its associated factors.

    Results

    A total of 2 507 patients were surveyed. Among them, 202 patients (8.1%) had only one condition, 1 712 patients (68.3%) had two conditions, and 593 patients (23.7%) had all three conditions. Statistically significant differences (P<0.05) were observed in the types of conditions present based on variables such as gender, place of residence, number of household members with hypertension, diabetes, and dyslipidemia, BMI, exercise habits, fasting blood glucose levels, lipid profiles, and family function score. The prevalence ratio for hypertension, dyslipidemia, and diadetes was 2.4∶2.4∶1. Among the comorbidity patterns, hypertension combined with diadetes was the most common (1 404 cases, 56.0%), followed by patients with all three conditions (593 cases, 23.7%). No statistically significant differences (P>0.05) were found in the distribution of different comorbidity patterns between genders or across age groups. The mean total family function score was (7.63±1.83). Significant differences (P<0.05) were found in the partnership, affection, and resolve sub-scores, as well as in the total family function scores, among patients with different disease patterns. Multivariate linear regression analysis identified gender (female: β=-0.148, t=-2.275, P=0.023), place of residence (apartment complex: β=-0.155, t=-2.402, P=0.016), and fasting blood glucose levels (abnormal glucose: β=-0.045, t=-2.465, P=0.014) as risk factors for lower total family function scores. On the other hand, the number of family members with hypertension, diabetes, and dyslipidemia (two or more: β=0.174, t=2.356, P=0.026) and the type of disease patterns ("comorbidity of two conditions": β=0.193, t=2.586, P=0.010; "comorbidity of all three conditions": β=0.342, t=3.248, P=0.001) were identified as protective factors for higher total family function scores.

    Conclusion

    Elderly patients with the hypertension, diabetes, and dyslipidemia in original residential community of Guangzhou metropolitan predominantly exhibit "a comorbidity of two conditions" pattern with generally good family function. Gender, place of residence, the number of family members with hypertension, diabetes, and dyslipidemia, type of diseases and fasting blood glucose are key influencing factors of family function.

    Preference Study on Family Doctor Contract Service among Patients with Hypertension and Type 2 Diabetes Mellitus
    CAO Chenchen, ZHENG Lyuyun, WANG Lin, LIU Jing
    2025, 28(16):  2011-2016.  DOI: 10.12114/j.issn.1007-9572.2024.0450
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    Background

    With the continuous development of the concept and practice of "patient-centered" medical and health service, the traditional family doctor contract service model, which focuses on single-disease treatment and management, cannot effectively meet the service needs of patients with multiple chronic diseases.

    Objective

    To explore that preference of patients with hypertension and type 2 diabetes for family doctor contract service in Hainan Province, and to provide empirical evidence for optimizing the contract service plan of family doctor.

    Methods

    A multi-stage stratified random sampling method was used to conduct a questionnaire survey from July 2023 to February 2024. The service preference of family doctors with hypertension and type 2 diabetes comorbid patients in Hainan Province was measured by discrete choice experiment (DCE). The set preference attributes were institutional nature, implementation environment, doctor's title, service mode, medication guidance and out-of-pocket expenses, service content attribute. A mixed Logit model was constructed with Python 3.11.7 software for preference analysis.

    Results

    A total of 581 questionnaires were sent out, and 558 were valid, with an effective recovery rate of 96.0%. Six attributes, including institutional nature, implementation environment, doctor's title, service mode, medication guidance and out-of-pocket expenses, had significant effects on patients' preference for family doctor contracted service (P<0.05). The service content attribute had no significant effect (P>0.05). Patients with HTN-T2DM prefer to choose government-run institutions, door-to-door service, priority referral, senior doctor title, 50 yuan/month and 2 weeks medication guidance.

    Conclusion

    The institutional nature being government-run is the most highly valued attribute for patients. Home visit services and priority referral are important attributes that influence the preference for family doctor contracted services. It is suggested that a personalized family doctor contract service plan based on the preferences of patients with chronic diseases and comorbidities be formulated with a patient-centered approach to promote the high-quality development of family doctor contract services.

    Prospective Cohort Study of the Impact of Socioeconomic Status and Healthy Lifestyle on Cardiovascular Disease
    AN Qinyu, WANG Yiying, ZHANG Xiaodan, ZHANG Tianlin, ZHAN Qingqing, ZHANG Fuyan, LIU Tao, WU Yanli
    2025, 28(16):  2017-2024.  DOI: 10.12114/j.issn.1007-9572.2024.0279
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    Background

    Cardiovascular disease (CVD) is a global health problem, and it is not known whether socioeconomic status (SES) and healthy lifestyle (HL) have an impact on CVD onset.

    Objective

    To understand the relationship between SES, HL and CVD, and to provide a basis for the prevention and control of CVD in the population.

    Methods

    A multi-stage cluster random sampling method was employed to select 9 280 residents aged 18 and above from 12 counties and districts in Guizhou Province as the baseline sample in 2010. In 2016-2020 follow the cohort, face to face interview by unified training and qualified personnel, including basic situation, lifestyle (smoking, drinking, vegetables and vegetables, etc.), previous disease history, according to the survey was divided into CVD group (123) and non-CVD group (4 025) ; we used COX proportional hazard regression models were used to analyze the effect of SES and HL on CVD incidence. Additionally, an accelerated failure time model was utilized to assess the impact of different SES and HL at the time of CVD onset.

    Results

    After excluding baseline CVD patients, lost-to-follow-up and missing information, the valid sample size included in the analysis was 4 148, CVD onset 123, and the incidence density was 4.13 / 1 000 person-years. The results of multivariate analysis showed that compared with low SES (≤7 points), the risk of CVD in high SES (>7 points) decreased by 40.60% (HR=0.594, 95%CI=0.402-0.878). Compared with 6 HL populations, the population with 8 and 9 HL decreased by 44.40% (HR=0.556, 95%CI=0.320-0.968) and 49.20% (HR=0.508, 95%CI=0.284-0.912). Compared with the population in the low SES group and with HL ≤ 6 conditions, there was no statistically significant risk of CVD incidence in the population in the low SES group with HL of 7, 8, or ≥ 9 conditions (P>0.05) ; those with high SES (>7 points) and HL of 8 or 9 decreased CVD risk by 61.80% (HR=0.382, 95%CI=0.163-0.894) and 70.20% (HR=0.298, 95%CI=0.119-0.748, respectively), showing a decreasing trend. The results of the accelerated failure time model showed that those with high SES (>7 points), those with 8 species and 9 HL were delayed by 1.148 years (95%CI=0.049-2.287) and 1.407 (95%CI=0.227-2.588) .

    Conclusion

    Different SES and HL are negatively associated with CVD onset; in high SES population, the duration of CVD onset increases with increasing HL species. Low SES population is the key population of CVD prevention and control in Guizhou Province, so measures should be taken to improve their health literacy, and the health education and health promotion of CVD should be carried out accordingly.

    The Body Mass Index, Dietary Knowledge Acquisition Level, Sedentary Time and Influencing Factors among Chinese High School Students
    JING Tao, DAI Yongmei, LUO Jianying, LUO Wei, JI Yelinfan, PENG Chi, ZHANG Cuijun, CAO Yanjun, ZHENG Qing, HUANG Yu, SHEN Hejun
    2025, 28(16):  2025-2032.  DOI: 10.12114/j.issn.1007-9572.2023.0922
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    Background

    In the context of the general implementation of online and offline blended teaching mode in China's high schools, it was necessary to understand the changes in body mass index (BMI), dietary knowledge acquisition level and sedentary time of high school students. However, there was a lack of multicenter, large-sample studies focusing on the relationship between the three.

    Objective

    To understand the BMI, dietary knowledge acquisition level and sedentary time of high school students in China, and to analyze their influencing factors, in order to provide empirical evidence for the promotion of physical and mental health development of high school students.

    Methods

    From January to March 2019, 6 213 high school freshmen and sophomores were selected as study subjects in 23 provinces in seven regions of China, namely east China, south China, north China, central China, northwest China, southwest China and northeast China, by using stratified random whole cluster sampling method. A self-designed questionnaire was used to conduct the survey, which involved 4 parts: students' personal and family information, BMI, dietary pagoda knowledge test (DPKT), and sedentary time. A total of 6 038 valid questionnaires were collected, and the effective recovery rate of the questionnaires was 98.35%.

    Results

    Comparison of BMI among high school students with different regions, provinces, grades, number of family members, and father's education showed statistically significant differences (P<0.05). Comparison of DPKT among high school students with different regions, provinces, number of family members, annual income of the family, father's education, and mother's education showed statistically significant differences (P<0.05). Comparison of sedentary time among high school students with different regions, provinces, urban/rural distributions, age, family population, annual family income, father's education, mother's education, the difference is statistically significant (P<0.05). The results of the multiple linear regression analysis indicate that BMI (β=-0.05), sedentary time (β=0.07), family size (β=0.03), father's education level (β=0.05), and family income (β=0.05) were influencing factors of DPKT scores among high school students (P<0.05). Additionally, DPKT scores (β=0.07), family size (β=-0.03), and father's education level (β=0.04) were influencing factors of sedentary time among high school students (P<0.05) .

    Conclusion

    The median BMI levels of high school students in urban and rural areas in seven regions of China were generally in the normal range, but the overall dietary knowledge acquisition level were low, and the problem of overall longer sedentary time was prominent. Dietary dietary knowledge acquisition level and sedentary time were the most influential factors on each other, and father's education was the main social factor influencing dietary DPKT score and sedentary time.

    The Influence of Chronic Disease Comorbidity on Activities of Daily Living in Rural Elderly in Mountainous Areas of Southern Ningxia Based on Latent Category Analysis
    SONG Mingsha, WANG Youyun, LI Chunsheng, QIAO Hui
    2025, 28(16):  2033-2038.  DOI: 10.12114/j.issn.1007-9572.2024.0278
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    Background

    With the acceleration of population aging, chronic disease comorbidities have become a major public health problem threatening the health of the elderly. There is a close correlation between chronic disease comorbidity and activity of daily living (ADL). However, there are few studies on the influence of chronic disease comorbidity and comorbidity pattern on ADL.

    Objective

    To understand the impact of chronic disease comorbidity on ADL, to provide a reference for improving the quality of life of the elderly.

    Methods

    From June to July 2022, a multi-stage stratified random cluster sampling method was used to conduct a face-to-face household survey among 20 821 residents in 4 counties of Ningxia Hui Autonomous Region, including demographic characteristics, chronic diseases, and ADL impairment. In this study, 4 362 elderly people (≥60 years) were included as subjects. Potential category analysis was used to determine comorbidity patterns, and Logistic regression was used to analyze the effects of chronic disease comorbidity and different comorbidity patterns on activities of daily living.

    Results

    The prevalence of chronic diseases among the elderly included was 62.52% (2 727/4 362), the prevalence of comorbidities was 23.75% (1 036/4 362), the ADL damage rate was 18.36% (801/4 362). Five comorbidity patterns were identified based on the latent category analysis, namely the coronary heart disease comorbidity group, the rheumatoid arthritis comorbidity group, the diabetes comorbidity group, the hypertension comorbidity group, and the multisystem disease comorbidity group. Adjusting for factors such as gender, age, educational level, marital status, occupation, annual per capita household income, smoking, alcohol consumption, exercise status, and self-rated health status, elderly people with comorbidity had 1.909 times (95%CI=1.581-2.305, P<0.05) risk of impaired ADL than those without comorbidity, older adults in the rheumatoid arthritis comorbidity group had a higher risk of impaired ADL than those in the coronary heart disease comorbidity group [OR (95%CI) =1.834 (1.245-2.701), P<0.05] .

    Conclusion

    Older adults with chronic comorbidities have a higher risk of ADL impairment than older adults without chronic comorbidities. There are differences in the risk of ADL impairment among the elderly with different comorbidity patterns of chronic diseases. The risk of ADL impairment in the elderly in the comorbidity group of rheumatoid arthritis is higher than that in the comorbidity group of coronary heart disease. Therefore, there is an urgent need to pay more attention to elderly people with chronic disease comorbidities, appropriate measures should be taken to improve their health and improve their quality of life.

    The Hospitalization Spending and Associated Factors in Inpatients with Multimorbidity in Township Health Centers in Guangxi
    ZHAO Can, SHEN Ying, XI Qian, PENG Houxuan, QIN Jinqiong, WANG Xuan, ZHENG Yanping, QIN Li, ZUO Yanli
    2025, 28(16):  2039-2049.  DOI: 10.12114/j.issn.1007-9572.2024.0103
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    Background

    In comparison to single chronic disease, multimorbidity significantly increase patients' hospitalization spending, economic burdens, and even the risk of poverty due to illness. Currently, the hospitalization spending and associated factors of patients with multimorbidity in rural primary health care facilities in our country still remain unclear, which hampers effective decrease in disease burden of multimorbidity among rural inhabitants.

    Objective

    This study aims to understand the hospitalization spending and associated factors of patients with multimorbidity in rural township health centers in Guangxi.

    Methods

    The study employed a combination of multiple-phased stratified sampling and cluster sampling, and randomly sampled 2 rural township health centers from five cities of Guangxi respectively, including Nanning, Wuzhou, Liuzhou, Yulin, and Guigang. The de-identified health records of all inpatients with multimorbidity admitted between Jan 1th, 2021 and Jun 30th, 2023 of 10 sampled township health centers in total were collected (n=9 330). The average expenditure per hospitalization and the hospitalization expenditure per capita for various number of co-existing chronic diseases and for prevalent multimorbidity patterns were compared, and multivariate unordered Logistic regression analysis was used for identification of factors associated with the average expenditure per hospitalization and the hospitalization expenditure per capita of patients with multimorbidity.

    Results

    The average expenditure per hospitalization for 9 330 patients with multimorbidity was 3 063.0 (2 384.5, 3 836.3) yuan, and the hospitalization expenditure per capita was 4 175.0 (2 704.0, 7 966.7) yuan. The patients with ≥5 co-existing chronic diseases demonstrated the highest levels of average expenditure per hospitalization and hospitalization expenditure per capita, as 4 535.7 (3 718.3, 5 288.2) yuan and 11 897.7 (6 536.5, 21 940.2) yuan, followed by those with 4 co-existing chronic diseases and the second highest levels as 3 894.2 (3 178.0, 4 562.2) yuan and 9 474.3 (4 854.9, 15 178.4) yuan, those with 3 co-existing chronic diseases and the third highest levels as 3 306.9 (2 649.5, 3 976.3) yuan and 4 926.0 (3 180.6, 8 793.8) yuan, and those with 2 co-existing chronic diseases and the lowest levels as 2 699.8 (2 075.4, 3 290.7) yuan and 3 196.0 (2 264.1, 5 292.3) yuan. The multimorbidity patterns ordered by prevalence were not identical to those by the level of hospitalization expenditure among patients with 2, 3, 4, ≥5 co-existing chronic diseases. The results of multivariate unordered Logistic regression analysis showed multiple factors, including age, ethnic group, vocation, medical insurance type, smoking history, BMI, number of co-existing chronic diseases, and hospitalization frequency, correlated with the average expenditure per hospitalization (P<0.05) ; similar factors, including gender, age, ethnic group, education level, marital status, medical insurance type, smoking history, and number of co-existing chronic diseases, were associated with the hospital expenditure per capita (P<0.05) .

    Conclusion

    The hospitalization spending of patients with multimorbidity positively correlates with number of co-existing chronic diseases in township health centers in Guangxi, and only one chronic disease added can lead to significant increases in both the average expenditure per hospitalization and the hospital expenditure per capita. Multimorbidity patterns with high prevalence were not identical to those with high hospitalization spending. Factors influencing hospitalization spending due to multimorbidity interact with each other intricately, emphasizing the need for comprehensive, multifaceted strategies to improve hospitalization spending of multimorbidity in rural areas and to reduce economic burden of multimorbidity amid rural residents.

    Investigation and Future Trend Prediction of Disease Burden of Elderly Type 2 Diabetes Mellitus Globally and in China from 1990 to 2021
    ZHAO Xiaoxiao, KE Lixin, XUN Yangqin, WANG Haibo, GAO Wulin, QIAO Tianci, LU Xiaohui, WU Jibiao, LU Cuncun
    2025, 28(16):  2050-2058.  DOI: 10.12114/j.issn.1007-9572.2024.0497
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    Background

    Type 2 diabetes mellitus (T2DM) among the elderly has become a significant public health problem both globally and in China, affecting population health. It is extremely urgent to clarify the related disease burden.

    Objective

    To assess the disease burden of T2DM among the elderly population globally and in China from 1990 to 2021, project future trends, and offer insights to inform public health and medical decision-makings.

    Methods

    Data on incidence and mortality burdens of individuals aged 60 years and above with T2DM in China and around the world were extracted from the global Burden of Disease (GBD) 2021 database. Age-standardized incidence and mortality rates were estimated based on the GBD 2021 standard population. Joinpoint regression was utilized to calculate the average annual percentage change (AAPC) for assessing disease burden trends. Subgroup analyses were performed based on age and sex, and decomposition analysis was performed to examine how aging, population growth, and epidemiological changes impacted disease burden. Bayesian models were employed to forecast prevalence and mortality between 2022 and 2035.

    Results

    In 2021, the global incidence of T2DM stood at 6 047 049, while in China, it reached 800 764, representing increases of 178.68% and 220.28%, respectively, compared to the incidence in 1990. Over the period from 1990 to 2021, the global age-standardized incidence rate exhibited a significant overall upward trend (AAPC=1.21%, P<0.001), whereas the trend in China was not statistically significant (AAPC=0.29%, P=0.189). The number of deaths among elderly T2DM patients in 2021 in the global and Chinese populations was 1 304 150 and 149 972, respectively, marking increases of 164.68% and 197.98% compared to the number of deaths in 1990. Throughout the same period, the global age-standardized mortality rate displayed a consistent upward trend (AAPC=0.32%, P<0.001), while the trend in China remained relatively stable (AAPC=0.01%, P=0.922). Notably, the number of incidence and mortality for female in 1990 and 2021, globally and in China, exceeded those of males. Meanwhile, the 60-64 age group had the highest proportion of incidences in 2021, while the 70-74 age group had the highest proportion of deaths. Population growth emerged as the primary influencer driving the rise in incidence and mortality in elderly T2DM patients in both global and Chinese populations, as revealed by decomposition analysis. The projection indicates a continued increase in the incidence and mortality of elderly T2DM patients worldwide and in China from 2022 to 2035.

    Conclusion

    The persistent heavy burden of incidence and mortality among elderly individuals with T2DM in both global and Chinese populations necessitates urgent reinforcement and formulation of more effective public health policies and clinical prevention and control strategies to alleviate the fundamental burden associated with this demographic.

    Consulting Room of General Practitioner
    Case Sharing of Closed-loop Management Based on the Prevention and Treatment Platform for Chronic Obstructive Pulmonary Disease
    JIN Feng, LI Wangling, XIE Fei
    2025, 28(16):  2059-2064.  DOI: 10.12114/j.issn.1007-9572.2024.0302
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    This dissertation introduces a case study on the "screen-diagnose-treat-manage" process for patients with chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) under a community-level COPD prevention and treatment platform. Explored how general practitioners can utilize their unique advantages, integrate various resources, and develop treatment plans based on individual patient conditions through questionnaire surveys, lung function tests, and comprehensive evaluations, in order to achieve early identification, accurate diagnosis, effective intervention, and comprehensive care for chronic obstructive pulmonary disease. This approach provides an innovative perspective and practical pathway for managing COPD at the community level. This enhances the ability of primary healthcare providers to effectively prevent and treat chronic obstructive pulmonary disease COPD, ultimately improving patient outcomes at the community level.