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    05 May 2025, Volume 28 Issue 13
    Special Research Report
    Evaluation and Measurement of Primary Health Services Based on Patients' Experience in China
    LIN Chunmei, LI Sisi, ZHANG Yanchun, ZHANG Lifang, QIN Jiangmei
    2025, 28(13):  1553-1559.  DOI: 10.12114/j.issn.1007-9572.2024.0275
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    Background

    Patients' experience as an important aspect of measuring and evaluating the quality of primary healthcare services, it's important to measure and evaluate it. However, the research about patients' experience in China started late, and there are even fewer studies focusing about patients who visit to the primary health care institutions.

    Objective

    To reflect the progress of primary healthcare services in China by measuring and evaluating patients' experience which from the primary health care institutions.

    Methods

    From March to April 2023, a patient questionnaire survey was conducted by trained and qualified investigators using an intercept method on patients of township health centers/community health service centers in 3 sample townships/streets in 12 national comprehensive primary health care pilot zones (hereinafter referred to as "the pilot zones"). The main survey tool was the Assessment Survey of Primary Care (ASPC) scale. In fact, 36 institutions and 1 157 patients were surveyed.

    Results

    The scores for the dimensions of the first visit/first line care, service accessibility, continuity of the patient relationship, comprehensive services, and coordinated services for the patients surveyed who received primary healthcare services were (69.5±20.5), (74.1±20.1), (72.0±20.7), (75.1±21.0), and (68.5±21.7) respectively, with the total score of the ASPC scale being (71.8±17.3). There were statistically significant differences (P<0.05) between patients of different ages, literacy levels, employment statuses, whether they were signed up or not with prationers, and whether they were with chronic diseases as well as in the different pilot zones in all dimension scores and in total scores. The results of the multivariate linear regression analysis show that age, employment statuses, signed up or not with prationers, and different pilot zones are the influencing factors for the scores of the first visit/first line care in patient (P<0.05), while employment statuses, signed up or not with prationers and different pilot zones are the influencing factors for the scores of the other four dimensions and the total score of the scale (P<0.05). After adjusting for other factors, the scores on the five dimensions and the total score of the ASPC scale were all lower in unemployed patients than in employed patients (P<0.05). The scores on the five dimensions and the total score of the ASPC scale were all higher in patients who had signed up with prationers than in those who had not (P<0.05). The total score of the ASPC scale was higher in patients from Changting County, Xishui County than in those from Jiexiu City (P<0.05), while it was lower in patients from Haiyan County, Lu County, Dongfang City than in those from Jiexiu City (P<0.05). The total score of the ASPC scale was not statistically significant in patients from Suixi County, Shouguang City, Jiaxian County, Xinyuan County, Miyun District, and Shangsi County compared with those from Jiexiu City (P>0.05) .

    Conclusion

    The scores of ASPC reflect the current situation of primary health care services in China. The implementation of the family doctor contract service enhances the patient's experience of the first visit to the primary health care institutions, accessibility of services, continuity of the doctor-patient relationship, comprehensive services, and coordinated services. The capacity and quality of primary health service delivery varies across the pilot zones. The difference in the experience score of primary outpatients in different experimental areas is related to "patient-centered" and convenience measures.

    Present Situation of TCM General Practitioners in China and Suggestions on Statistical Optimization
    SHI Muran, WU Ning, SONG Lijuan
    2025, 28(13):  1560-1566.  DOI: 10.12114/j.issn.1007-9572.2024.0389
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    Background

    General practitioners of traditional Chinese medicine (TCM), known as the "gatekeepers" of residents' health, provide continuous services to them. Recently, China has rolled out a series of policies aimed at supporting the growth of the workforce of TCM general practitioners and has made it a key development indicator, which holds great importance for advancing the TCM cause.

    Objective

    In alignment with the development goals outlined in the "14th Five-Year Plan" for the Development of TCM, this study analyzes the current status of the TCM general practitioner workforce in China, explores the optimization of statistical methodologies for TCM general practitioners, and proposes corresponding countermeasures and suggestions.

    Methods

    Based on data from the China Health Statistics Yearbook from 2021 to 2023 and special survey data, the difference between the actual number of TCM general practitioners in 2020 and 2022 and the planned number for 2025 was calculated. The completion rate of the planning targets was then computed based on these differences. A comparative method was used to analyze the data.

    Results

    In 2022, the number of TCM general practitioners per 10 000 population was 0.75, representing an increase of 13.27% compared to 2020, with an average annual growth rate of 6.43%. There were significant regional disparities in the distribution of TCM general practitioners per 10 000 population, with the eastern, central, and western regions decreasing in that order, at 0.88, 0.68, and 0.61 respectively. The national completion rate for the TCM general practitioner workforce plan was 66.76%, indicating good overall progress. A total of 17 provinces (municipalities, autonomous regions) achieved a completion rate of 40% or higher for their TCM general practitioner workforce planning targets, with 11 of them exceeding their targets. Additionally, 14 provinces (municipalities, autonomous regions) made slower progress, including 9 provinces where the completion rate was negative. Based on special assessment data, calculations were made for TCM general practitioners from the perspectives of functional positioning and scope of practice, with 9 provinces and 20 provinces achieving their planning targets ahead of schedule, respectively.

    Conclusion

    Currently, the statistical count of TCM general practitioners is directly influenced by the number of general practitioners, leading to significant impacts on the count of TCM general practitioners when there are changes in the statistical criteria for general practitioners. It is necessary to further clarify the definition and statistical scope of TCM general practitioners, and strengthen the monitoring and evaluation of TCM general practitioner indicators to ensure the smooth achievement of planning targets.

    Frontiers and Hotspots
    Research on the Digital Traditional Chinese and Western Medicine Collaborative Health Governance Model Based on the Logic of Health Co-prosperity
    NI Minhan, WU Zhihan, ZHOU Siyu, HUANG Xianhong, SUN Tao, WANG Xiaohe, CUI Linlin
    2025, 28(13):  1567-1572.  DOI: 10.12114/j.issn.1007-9572.2023.0770
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    Health co-prosperity is the conceptual interpretation and application extension of the logic of common prosperity in the field of health. Building a digital collaborative health governance model between Chinese and western medicine based on the advantages of digital reform is the "Zhejiang Model" of health co-prosperity and helps to achieve the goal of high-quality full life cycle medical and health services. This article is based on the collection of relevant policies on the digital collaboration between Chinese and western medicine during the construction of the Common Prosperity Demonstration Zone in China and Zhejiang Province. It elaborates on the definition and connotation of health co-prosperity, and selects the digital Chinese and western coordinated health governance model of provincial, grassroots platforms, and medical institutions in Zhejiang Province as a specific case to explain the theme and path of the system design logic, grassroots platform logic, and institutional service logic of health co-prosperity, to provide reference and suggestions for the innovative construction and optimization of the collaborative health governance model between Chinese and western medicine.

    The Current Status and Challenges of Integrative Chinese and Western Medicine in the Treatment and Management of Prediabetes from a Proactive Health Perspective
    PENG Hongye, LU Chunli
    2025, 28(13):  1573-1582.  DOI: 10.12114/j.issn.1007-9572.2024.0242
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    As an early stage of diabetes, prediabetes is closely related to the increased risk of diabetes, cardiovascular disease, and even death, which seriously harms national health and has become the core of major chronic disease management. Proactive health emphasizes individual health as the center, with the characteristics of prevention, autonomy, precision, and personalization, covering prevention, diagnosis, treatment, rehabilitation, and other aspects, and is an important strategy to promote the strategy of Healthy China. Through systematic combing of relevant domestic and foreign guidelines, it was found that the concept of proactive health is widely used in the treatment and management of prediabetes, covering a variety of aspects such as lifestyle adjustment (diet, exercise, weight management), traditional Chinese medicine (Chinese herbal medicine compound, proprietary Chinese medicines, tea replacement, acupuncture, acupuncture point embedding, tuina massage, etc.), and western medicine (metformin, acarbose, glucagon-like peptide 1 receptor agonists, etc.). The combination of Chinese and western medicine in the treatment of pre-diabetes can achieve an organic integration of "overall regulation" and "precise treatment". This approach can reduce the dosage of western medicines, minimize toxic side effects, and lower medical costs, enabling patients to maintain a healthy state in the long term. However, due to the problems of low public awareness and attention and the lack of quantifiable and standardized clinical practice guidelines for lifestyle and treatment strategies combining TCM and western medicine, it is necessary to use social media to raise public awareness in the future, to carry out high-quality, large-sample, whole-population, randomized controlled trails, and to formulate practical guidelines for lifestyle guidance accordingly. Combining modern science and technology to explain the mechanism of Chinese medicine, to promote its application in the treatment of pre-diabetes, to realize the effective integration of Chinese and western medicine, to enhance the efficiency of comprehensive management of the disease.

    General Practice Education
    Current Situation and Reflection on Enrollment of Professional Doctoral Students in General Practice
    ZHANG Xueyuan, XIE Chenmei, LI Ruofan, ZHANG Wanxue, JIA Jinzhong
    2025, 28(13):  1583-1589.  DOI: 10.12114/j.issn.1007-9572.2023.0815
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    Background

    Professional doctoral students in general practice are the important component of academic education in general practice, but the related research on their enrollment is still insufficient.

    Objective

    The aim was to understand the scale and distribution of enrollment of professional doctoral students in general practice in China, and provide reference for promoting the development of general practice education.

    Methods

    From February 2022 to September 2023, data from general practitioner doctoral enrollment information through the official website of 51 schools with clinical medical doctoral first level discipline doctoral programs nationwide and the China Graduate Enrollment Information Network was obtained. The data was analyzed to illustrate the enrollment scale, distribution of enrollment institutions and enrollment structure of professional doctoral students.

    Results

    From 2021 to 2023, there were 15, 17 and 17 universities respectively enrolling professional doctoral students in general practice, and the enrollment quota was 100 in total. These enrollment universities were mainly concentrated in the eastern region. Medical universities had a relatively low proportion. These enrollment universities were mainly concentrated in B-level of discipline and the proportion of double first-class universities was not high.

    Conclusion

    Based on the investigation, it was found that there was a small number of institutions offering the professional doctoral education in general practice, with a limited enrollment scale and uneven distribution of participating institutions. Prominent issues such as weak faculty teams were also identified. Therefore, it is recommended to strengthen top-level design at the national and university levels, enhance enrollment promotion efforts, establish scientific admission standards, student support policies, and optimize the selection system for supervisors. These measures could expand the channels for enrolling professional doctoral students in general practice, and provide strong support for cultivating high-end medical professionals with comprehensive medical service capabilities.

    The Current Status of Doctor-Patient Communication Skills among General Practice Master's Students and the Role of Supervisors' Influence
    ZHAO Tiefu, ZHANG Bin, HAN Hongya, LUO Hongchi, MA Hanying
    2025, 28(13):  1590-1594.  DOI: 10.12114/j.issn.1007-9572.2024.0202
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    Background

    More and more attention has been paid to the training of medical students' doctor-patient communication skills. It was necessary to improve the doctor-patient communication skills of general medicine postgraduates.

    Objective

    To explore the current situation of doctor-patient communication ability of postgraduates in general medicine and the influence of mentors on it.

    Methods

    A total of 72 full-time postgraduate students majoring in general practice, who were being supervised by 66 full-time postgraduate supervisors from the School of General Practice and Continuing Education of Capital Medical University from January to December 2023, were selected as the research subjects. The doctor-patient communication skills of the postgraduate students and their supervisors were evaluated using the SEGUE scale, and evaluate the gap between them and Beijing general practitioners and outpatient doctors in tertiary hospitals; the correlation analysis between the communication ability of the supervisors and the students in Pearson.

    Results

    The professional master's degree students majoring in general practice scored lower than Beijing general practitioners in the dimensions of preparation, information collection, information provision, understanding patients, ending the consultation and the total score (P<0.05), and scored lower than the general practitioners in the tertiary grade A hospitals in Beijing in the dimensions of information collection, information provision, ending the consultation and the total score (P<0.05). According to whether the main clinical training unit is the supervisor group, the graduate students are divided into the accompanying supervisor group and the not accompanying tutor group. The preparation stage, information collection dimension score and total score of the accompanying tutor group were higher than the unrelated tutor group (P<0.05). With the supervisor group, the preparation stage, information collection, information giving, patient understanding, end of the SEGUE scale and the total score were positively correlated (P<0.05). A positive correlation was observed between the graduate students and the supervisor SEGUE scale in the supervisor group (P<0.05) .

    Conclusion

    The doctor-patient communication skills of general medicine postgraduates need to be further improved. The doctor-patient communication skills of postgraduates were closely related to their tutors. Appropriate optimization of the training mode of general medicine postgraduates should help to improve the doctor-patient communication skills of general medicine postgraduates.

    Original Research
    The Influencing Factors of Depression Symptoms in the Chinese Female Elderly Population Based on Health Ecology Models
    ZHANG Ying, JIANG Xintong, WANG Pingyu
    2025, 28(13):  1595-1600.  DOI: 10.12114/j.issn.1007-9572.2024.0297
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    Background

    The elderly population in our country is large and growing rapidly, and depression is a common emotional disorder and mental health problem among the elderly population. The mental health of the female elderly population is increasingly becoming a focus of social concern.

    Objective

    To explore the influencing factors of depression symptoms in the female elderly population from a multi-level and comprehensive perspective of health ecology, and provide theoretical basis for identifying and intervening in depression symptoms in the elderly female population in China.

    Methods

    In January 2024, we extracted for the 2020 survey data from the China Health and Retirement Longitudinal Survey (CHARLS), and a group of female elderly adults aged 60 years and above were selected for the study (n=4 594). Based on the health ecology model, the influencing factors were divided into five levels: personal characteristics layer, behavioural characteristics layer, interpersonal network layer, living and working conditions layer, and policy environment layer. The χ2 test and binary Logistic regression model were used to explore the influencing factors of depression symptoms and to establish a health ecology model of depression symptoms in the Chinese female elderly population.

    Results

    The detection rate of depression symptoms in the Chinese female elderly population was 48.06% (2 208/4 595). Logistic regression analysis showed that age of ≥80 years (OR=0.601, 95%CI=0.449-0.804), sleep duration of≥6 h (OR=0.561, 95%CI=0.493-0.639), satisfaction with life (OR=0.256, 95%CI=0.199-0.330), better self-rated physical health (OR=0.459, 95%CI=0.395-0.533), urban household registration (OR=0.717, 95%CI=0.603-0.853), satisfaction with children (OR=0.666, 95%CI=0.472-0.940), education level of junior high school and above (OR=0.712, 95%CI=0.582-0.871), family income >50 000 yuan (OR=0.822, 95%CI=0.704-0.959) and the per capita GDP of the city is 50 000 to 100 000 yuan (OR=0.841, 95%CI=0.730-0.970) were the protective factors for the development of depression symptoms in the Chinese female elderly population (P<0.05). Having become disabled (OR=1.786, 95%CI=1.556-2.050), suffering from chronic diseases (OR=1.159, 95%CI=1.014-1.324), central region (OR=1.298, 95%CI=1.107-1.522) and western region (OR=1.407, 95%CI=1.183-1.675) were the risk factors for depression symptoms in the Chinese female elderly population (P<0.05) .

    Conclusion

    The detection rate of depression symptoms in the Chinese female elderly population is relatively high, and there are many influencing factors, including: age in the personal characteristics layer; sleep time, satisfaction with life, self-related of physical health, disability, and chronic disease in the behavioral characteristics layer; household registration type, satisfaction with children, and geographical distribution in the interpersonal network layer; education and family income in the living and working conditions layer; the per capita GDP of the city in the policy environment layer. Effective intervention measures should be taken at all layers, targeting key populations, in order to reduce the incidence of depression symptoms among the Chinese elderly women.

    Association between Sleep Efficiency and Dyslipidemia among Adults Aged 40 to 65
    WANG Die, WU Bangyun, TAN Cunyao, SHEN Shihui, LI You, MENG Yue, WANG Dashan, HU Jin, WANG Ziyun, WANG Junhua
    2025, 28(13):  1601-1606.  DOI: 10.12114/j.issn.1007-9572.2024.0197
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    Background

    Lipid metabolism of middle-aged and older adults may be influenced by decreased sleep efficiency, but their association still needs to be analyzed in-depth.

    Objective

    To analyze the association between sleepefficiency (SE) and different lipid indexes in people aged 40-65, and to explore the mediating role of central obesity in the association between SE and lipid to provide reference for exploring the pathway of dyslipidemia caused by SE and its prevention and treatment.

    Methods

    From March to November 2022, the subjects who met the inclusion and exclusion criteria for physical examination in the physical examination center of Fuquan First People 's Hospital were investigated, including face-to-face questionnaire survey, physical examination and laboratory index detection. The minimum control variable set that needs to be adjusted to identify the association between SE and dyslipidemia through directed acyclic graph (DAG) was: age, gender, smoking, drinking, family income, exercise and education level. Non-conditional binary Logistic regression analysis was used to explore the association between SE and different dyslipidemia indicators.

    Results

    A total of 1 095 subjects were included in this study and were divided into two groups according to the presence or absence of dyslipidemia. There were statistically significant differences in gender, smoking, drinking, exercise, waist circumference, hip circumference and waist-hip ratio between the two groups (P<0.05). After adjusting control variables, higher risk hypertriglyceridemia was observed in the group with low SE than high SE group (OR=1.35, 95%CI=1.03-1.77), there was no statically significant association between SE and other lipid indexes. Mediation effect analysis showed that WHR had a partial mediating effect in the association between SE and hypertriglyceridemia (β=0.019, 95%CI=0.005-0.034), WHR played a masking effect on the association between SE and low high-density lipoprotein cholesterol .

    Conclusion

    Central obesity may be an important pathway in the association between low SE and hypertriglyceridemia.

    The Bidirectional Temporal Causal Association Study between Dysglycaemia and Non-alcoholic Fatty Liver Disease: Based on the Beijing Health Management Cohort
    NI Xuetong, AHEYEERKE Halengbieke, TANG Jianmin, CAO Tengrui, TAO Lixin, ZHENG Deqiang, LI Qiang, HAN Yumei, YANG Xinghua
    2025, 28(13):  1607-1613.  DOI: 10.12114/j.issn.1007-9572.2023.0792
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    Background

    Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and the prevalence of NAFLD in China has continued to increase over the past 20 years. Some cohort studies have confirmed the causal relationship between NAFLD and dysglycaemia, but the temporal relationship between the two remains unclear.

    Objective

    To analyse the bidirectional time-series association between NAFLD and dysglycemia using cross-lagged panel models with the Beijing Health Management Cohort as the study population.

    Methods

    Based on the Beijing Health Management Cohort Study, follow-up data were collected from 2016 to 2021, with one follow-up visit per year, including questionnaire and physical examination information. According to the pre-established inclusion and exclusion criteria, 44 838 study subjects were finally included. A cross-lagged panel model was constructed using hepatic steatosis (HS) and fasting plasma glucose (FPG) as surrogate indicators of NAFLD and dysglycaemia, and stratified by gender and BMI to explore the temporal relationship between NAFLD and dysglycaemia in different populations.

    Results

    (1) In the total population, the cross-lagged path coefficient βbaseline HS→follow-up FPG was statistically significant (P<0.05) at 0.009 (95%CI=0.002-0.016) ; however, the cross-lagged path coefficient in the opposite direction was not statistically significant (P>0.05). (2) In women, the cross-lagged path coefficients in both directions were statistically significant (P<0.05) with βbaseline HS→follow-up FPG of 0.025 (95%CI=0.015-0.035), and βbaseline FPG→follow-up HS of 0.026 (95%CI=0.014-0.038) ; in men, the cross-lagged path coefficients in both directions were not statistically significant (P>0.05). (3) Among those with BMI≥25.0 kg/m2, the cross-lagged path coefficient βbaseline HS→follow-up FPG was statistically significant (P<0.05) at 0.114 (95%CI=0.103-0.125) ; however, the cross-lagged path coefficients in the opposite direction were not statistically significant (P>0.05) ; and among those with BMI <25.0 kg/m2, the cross-lagged path coefficients in both directions were statistically significant (P>0.05). Cross-lagged path coefficients were statistically significant (P<0.05), with βbaseline HS→follow-up FPG of 0.101 (95%CI=0.092-0.111) and βbaseline FPG→follow-up HS of 0.021 (95%CI=0.012-0.031) .

    Conclusion

    There was a unidirectional temporal relationship from NAFLD to dysglycaemia in the total population and in the population with BMI≥25.0 kg/m2; and there was a bidirectional temporal relationship between NAFLD and dysglycaemia in the female population and in the population with BMI<25.0 kg/m2, which provides clues for adopting the treatment idea of co-prevention of the two disorders, NAFLD and dysglycaemia, in clinical practice.

    The Relationship between Suicidal Ideation and Childhood Trauma in Adolescents with Depressive Disorder: the Dual Mediating Effects of Depressive Symptom Severity and Low Vitamin D Levels
    ZHAO Lili, LIU Lewei, GENG Feng, MO Daming, LIU Huanzhong
    2025, 28(13):  1614-1621.  DOI: 10.12114/j.issn.1007-9572.2024.0298
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    Background

    Childhood trauma is a risk factor for suicidal ideation in patients with depressive disorder, and plasma vitamin D level is also related to suicidal ideation. However, there is still insufficient research on the relationship between them in adolescent patients with depressive disorder.

    Objective

    To explore the relationship between suicidal ideation and childhood trauma and to analyze the mediating role of depressive symptom severity and low vitamin D levels.

    Methods

    Adolescent patients with depressive disorder who attended Chaohu Hospital of Anhui Medical University and the Fourth People's Hospital of Hefei City in 2021 were used as the depressive disorder group (n=168), and adolescents with no history of mental illness recruited during the same period were used as the control group (n=89). Childhood trauma, depressive symptoms, and suicidal ideation were assessed using the Childhood Abuse Questionnaire (CTQ), the Current Evaluation of Depression Scale (CES-D), and the Suicidal Ideation Scale (PANSI), and plasma 25-hydroxyvitamin D[25 (OH) D] levels were also tested. Differences between adolescents with depressive disorders and control adolescents in suicidal ideation, depressive symptoms, childhood trauma, and vitamin D levels were compared; Pearson correlation analyses were used to test the correlation of scores on each scale, and the mediating roles of depression and vitamin D levels between childhood trauma and suicidal ideation were analyzed by the PROCESS macro program.

    Results

    Adolescents in the depressive disorder group had higher PANSI scores, CTQ subscale scores, and total scores than those in the control group (P<0.05), and lower 25 (OH) D levels than those in the control group (P<0.5). Pearson correlation analyses showed that there were correlations between the PANSI scores and the CTQ total scores, the CES-D scores, and the 25 (OH) D levels of adolescents in the depressive disorder group (P< 0.05), and the PANSI scores of adolescents in the control group were correlated with total CTQ scores, CES-D scores (P<0.05), and no correlation with 25 (OH) D levels (P>0.05). The mediation benefit analysis showed that the CES-D score and 25 (OH) D level in the adolescent group with depressive disorder played a partial mediating role between the CTQ total score and PANSI score, with mediation effects accounting for 61.8% and 5.3%, respectively; and a partial mediating role between the CTQ affective abuse subscale score and PANSI score, with mediation effects accounting for 58.9% and 6.5%; a partial mediating role between CTQ emotional neglect subscale scores and PANSI scores, with mediating effect percentages of 67.2% and 5.6%, respectively; and a full mediating role between CTQ somatic neglect subscale scores and PANSI scores, with mediating effect percentages of 92.2% and 7.8%. None of the mediating effects of 25 (OH) D levels were significant for control adolescents; CES-D scores played a fully mediating role between CTQ total scores and PANSI scores, and between CTQ emotional maltreatment subscale scores and PANSI scores; and a partially mediating role between CTQ emotional maltreatment subscale scores and PANSI scores, with a direct effect percentage of 41.5% and a mediating effect accounted for 58.5%; the mediating effect between CTQ somatic neglect subscale scores and PANSI scores was not significant.

    Conclusion

    The severity of depressive symptoms and low vitamin D levels in patients with adolescent depressive disorder are potential mechanisms of childhood trauma leading to suicidal ideation. In view of the disorder of childhood trauma of adolescent depression in clinical should be timely and effective control and improvement of patient, improve their vitamin D levels and actively carry out mental health education, in order to reduce the occurrence of suicidal ideation, improve clinical outcomes.

    Efficacy and Safety of Long-acting Risperidone Microspheres in the Maintenance Treatment of Schizophrenia
    LIU Caiping, ZHANG Yanhua, TANG Jianpin, WANG Chengpeng, XUE Fengfeng, WANG Huijuan, LI Chuanwei, ZHANG Guangya, LI Huafang
    2025, 28(13):  1622-1627.  DOI: 10.12114/j.issn.1007-9572.2023.0859
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    Background

    Long-acting antipsychotics are one of the important choices in the maintenance treatment of patients with schizophrenia, which can effectively prevent relapse. Risperidone microspheres for injection (Ⅱ) has been improved in dosage form to maintain steady-state concentration, however there is currently a lack of study for efficacy on maintenance phase treatment.

    Objective

    To evaluate the efficacy and safety of risperidone microspheres for injection (Ⅱ) in the maintenance treatment for schizophrenia.

    Methods

    This was a single-arm, self-controlled, multicenter study. From May 2021 to May 2022, patients with schizophrenia, aged 18-65 years, were enrolled from 3 centers: Shanghai Mental Health Center, Hangzhou Seventh People's Hospital, and Suzhou Guangji Hospital. All patients switched from oral risperidone to risperidone microspheres for injection (Ⅱ) for maintenance treatment. During the treatment period, 25.0 mg, 37.5 mg or 50.0 mg were injected every two weeks, followed up for 12 weeks. At baseline, and at the end of 2, 4, 8, and 12 weeks, the social functioning was assessed using the Personal and Social Functioning Scale (PSP) ; the clinical symptoms and overall changes were assessed using the Positive and Negative Symptoms Scale (PANSS) and the Clinical Global Impression Scale (CGI) ; the health status was assessed using the European Five-Dimensional Survival Quality Inventory (EQ-5D) ; The Simpson-Angus Scale (SAS), Barnes Akathisia Rating Scale (BARS), and Abnormal Involuntary Movement Rating Scale (AIMS) were used to assess the extrapyramidal symptoms (EPS), and the laboratory indices were also collected.

    Results

    A total of 71 patients were included in the study. The total PSP scores of patients at the end of the 2, 4, 8 and 12 weeks of treatment were (48.20±24.65), (49.07±25.81), (50.46±26.96), and (51.85±28.16), respectively, which were higher than the baseline (43.89±22.32) (P<0.05). The PANSS total score, positive symptom scale, negative symptom scale, and general psychopathology scale scores were reduced at the end of 12 weeks of treatment compared with baseline (P<0.05). CGI-S scores were lower than baseline (P<0.05), CGI-I scores were significantly reduced at the end of 12 weeks compared with the end of 4 weeks after treatment (P<0.01), and EQ-5D scores were higher than baseline (P<0.05). Common adverse reactions were increased prolactin, EPS, and dizziness, and no serious adverse reactions (SAE) or drop-out patients due to AE were observed.

    Conclusion

    Risperidone microspheres for injection (Ⅱ) can effectively improve the clinical symptoms of schizophrenia in the maintenance period, and it is well tolerated.

    The Utilization and Influencing Factors of Community Electronic Health Records
    HE Meiliang, LIU Xiuliang, ZHAO Meigui, GUO Yanfang, XU Ying
    2025, 28(13):  1628-1634.  DOI: 10.12114/j.issn.1007-9572.2024.0125
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    Background

    Since its implementation, residents' electronic health records have achieved phased results. The target of the filing rate in Shenzhen, Guangdong Province has been achieved, and the utilization rate has become the core index of theoptimization management of this work.

    Objective

    To understand the use of electronic health records of residents in Bao'an District, Shenzhen, and to analyze the influencing factors. It provides a basis for improving the utilization rate of health records and optimizing the allocation of community health resources.

    Methods

    As of 2022-12-31, Shenzhen Community Health Service information system had a total of 4 077 665 electronic health records of Bao 'an District residents. 403 700 electronic health records were selected by systematic sampling method, and 401 853 meeting the requirements of the study were selected for analysis.

    Results

    The utilization rates of health records in 1 year, 2 years and 3 years were 59.30% (238 131/401 853), 74.90% (301 032/401 853) and 80.10% (321 853/401 853). The results of multivariate Logistic regression analysis showed that age, nationality, resident type, marital status, education level, profession, payment methods for medical expenses, duration of filing, as well as whether the health records were signed by a family doctor, the elderly, the hypertension and the diabetes were residents' electronic health records influencing factors of 1, 2 and 3 years use (P<0.05). Among them, compared with residents aged 21-45, the use rate of electronic health records in 1, 2 and 3 years was higher for residents aged 0-1, 2-3 and 4-6 years (OR>1.00, P<0.05) ; the usage rate of electronic health records for residents aged 46-60 and ≥61 years was lower in 1, 2 and 3 years (OR<1.00, P<0.05) ; compared with non-resident residents of Shenzhen, the use rate of electronic health records of residents with permanent residence in Shenzhen was higher at 1, 2 and 3 years (OR>1.00, P<0.05) ; compared with the residents participating in the basic medical insurance for urban employees, the use rate of electronic health records of residents with basic medical insurance, full self-payment and other medical expenses payment methods for urban residents was lower in 1, 2 and 3 years (OR<1.00, P<0.05) ; compared with residents with a filing period of<1 year, the use rate of electronic health records of residents with a filing period of≥1 year was lower at 1, 2 and 3 years (OR<1.00, P<0.05) ; compared with the residents without the corresponding project identification, the 1-year utilization rate of electronic health records with family doctor contract identification, elderly project identification, hypertension project identification, and diabetes project identification was higher[OR (95%CI) was 3.77 (3.70-3.84), 2.73 (2.53-2.94), 4.40 (4.11-4.72), 3.10 (2.78-3.47), P<0.05], respectively, and the 2-years and 3-years usage rates were also higher (OR>1.00, P<0.05) .

    Conclusion

    The usage rate of electronic health records among residents in Bao'an District has risen compared to previous levels, but there is still potential for further enhancement. Priority should be given to non-elderly people, middle-aged and elderly people identified by the hypertension/diabetes program, and residents who have not signed a family doctor, basic medical insurance for urban residents, payment methods for self-payment and other medical expenses, and non-household registration residents.

    A Retrospective Cohort Study on Health Examination of Elderly Population in Huangpu District, Guangzhou
    LI Dongxing, NIU Zimin, WANG Haoxiang
    2025, 28(13):  1635-1641.  DOI: 10.12114/j.issn.1007-9572.2024.0359
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    Background

    The aging of Chinese society has intensified, and the health of the elderly is a matter of great concern. As a densely populated and economically active area, the health of the elderly population in Huangpu District, Guangzhou City, is particularly important to the social and economic development of the local community. Therefore, regular monitoring and assessment of the health of the elderly population in Huangpu District can help identify potential health problems, prevent and control chronic diseases, and improve health literacy and self-care ability.

    Objective

    This study collects data on health checkups of the elderly population in Huangpu District and establishes a retrospective cohort to gain an in-depth understanding of the health status of the elderly population in the district, the influencing factors of diseases, and to provide reasonable suggestions for the development of targeted health interventions to improve the quality of life of the elderly.

    Methods

    Physical examination data were collected from 2019-2021 from Huangpu District, Guangzhou City, who participated in community health checkups and were≥65 years old, and the study involved basic information, history of living habits, auxiliary examinations, laboratory tests, and history of previous illnesses of the study subjects. Logistic regression analysis was performed on the influencing factors of the diseases.

    Results

    A total of 17 412 study subjects were included in the analysis of this study. In the "baseline-follow-up" cohort, there were statistically significant differences (P<0.05) in the prevalence of exercise, smoking, alcohol consumption, diastolic blood pressure, BMI, waist circumference, fasting blood glucose, blood creatinine, glomerular filtration rate, triglyceride, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), hypertension, diabetes mellitus, dyslipidemia, and chronic kidney disease (CKD). Differences in terms of were statistically significant (P<0.05). The proportion of developing hypertension, diabetes mellitus, dyslipidemia, or CKD at follow-up in the cohort population was 3.07%, 7.25%, 21.92%, and 6.00%, respectively. In participants with new-onset chronic disease at follow-up, 45.63% had comorbidities. Multifactorial logistic regression analysis: Risk factors for the prevalence of hypertension included age, pulse rate, and BMI; glomerular filtration rate and HDL-C were protective factors. Risk factors for the development of diabetes mellitus included age, systolic blood pressure, and BMI; and HDL-C was the main protective factor (P<0.05). Risk factors for dyslipidemia include systolic blood pressure. Risk factors for the development of CKD include age, systolic blood pressure, fasting blood glucose, and triglycerides (P<0.05) ; HDL-C was a protective factor (P<0.05) .

    Conclusion

    The prevalence of dyslipidemia was higher among the study population in the present study, followed by diabetes mellitus and CKD. Multiple chronic diseases predominantly suffer from both diseases. Age, systolic blood pressure, and BMI were the main risk factors for the development of chronic diseases among the elderly people who participated in the physical examination in this study. In response to the analysis, it is recommended to make full use of the health records based on the optimization of information technology, implementation of targeted interventions, leveraging community strengths as well as strengthening health education and health promotion to improve the health of the elderly.

    Reliability and Validity of the Chinese Version of the Modified COVID-19 Yorkshire Rehabilitation Scale
    DENG Jie, TAO Liyuan, LIU Nan, LI Jun, YAN Wenxin, QIN Chenyuan, LIU Qiao, DU Min, WANG Yaping, LIU Jue
    2025, 28(13):  1642-1648.  DOI: 10.12114/j.issn.1007-9572.2023.0554
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    Background

    The modified COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm) has been shown to be useful to assess and monitor patients in post-COVID-19 syndrome in developed countries. However, its reliability and validity in the Chinese population remains unclear.

    Objective

    To translate the C19-YRSm into a Chinese version (C19-YRSm-C), and test the reliability and validity of the Chinese version.

    Methods

    After obtaining the approval of the translation and use authority of the C19-YRSm from MANOJ SIVAN's team at the University of Leeds, United Kingdom, the research team translated the C19-YRSm and formed the C19-YRSm-C after translation, back-translation, and cross-cultural adaptation, according to the Translation and Cross-cultural Adaptation Procedure. From May 1 to 7, 2023, a simple random sampling method was used to select post COVID-19 patients from the "Wen Juan Xing" platform sample pool as the study subjects. The General Information Questionnaire and the C19-YRSm-C were used to survey them. 13 experts were invited to evaluate the content validity of the scale. The C19-YRSm-C was subjected to item analysis, reliability and validity analysis.

    Results

    A total of 512 questionnaires were distributed and 370 valid questionnaires were recovered, with a valid recovery rate of 72.3%. The results of item analysis showed that the CR values of the items ranged from 6.589 to 22.725 (P<0.001), and the item-total correlation coefficients of the scale ranged from 0.460 to 0.815 (P<0.001). For reliability, the Cronbach's α coefficient, Guttman Split-half coefficient and test-retest reliability of the C19-YRSm-C was 0.881, 0.837 and 0.833, respectively. For content validity, the item-level content validity index (I-CVI) of the C19-YRSm-C ranged from 0.692 to 1.000, and the scale-level validity index (S-CVI) was 0.914. The results of confirmatory factor analysis (CFA) showed that the fitting indicators of the initial model were undesirable. After the establishment of a covariance correlation between error variables e12 and e13 according to the indication prompts, the fitting indicators of the modified model were within the acceptable range except for the adjusted goodness-of-fit index (AGFI). The results of discriminant validity analysis showed that the differences in scores for the 4 subscales of the C19-YRSm-C among post-COVID-19 patients with different chronic disease history and cumulative number of COVID-19 showed statistically significant differences (P<0.05). The differences were statistically significant when comparing the scores of the 3 subscales in addition to other symptoms before and after COVID-19 infection (P<0.05) .

    Conclusion

    The C19-YRSm-C has good reliability and validity, with good applicability in Chinese population, which can be used to assess and monitor the rehabilitation status of post COVID-19 patients in China.

    Original Research·Focus on Treatment-prevention Integration
    Evaluation and Improvement Countermeasures Research of the Current Situation of Integrated Outpatient Service for Chronic Diseases in County Medical Community in Zhejiang Province from the Perspective of Medical Prevention Integration
    LIN Xiaoling, QU Kaixiao, LI Xu, CHEN Jingchun, HUANG Qunfang, ZHOU Chi
    2025, 28(13):  1649-1654.  DOI: 10.12114/j.issn.1007-9572.2024.0296
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    Background

    In order to promote the hierarchical diagnosis and treatment system and the construction of healthy China, the General Office of the State Council clearly pointed out that a medical community should be established in the county. Zhejiang Province took the lead in exploring the integrated outpatient service of chronic diseases in the construction of medical community. At present, the research on the integrated outpatient service of chronic diseases in China mainly focuses on the discussion of concepts, and less quantitative research is carried out on the current situation of services.

    Objective

    To analyze the current situation of the integrated outpatient service of chronic diseases in county medical communities in Zhejiang Province and explore its influencing factors, so as to provide countermeasures and suggestions for improving the operation of the integrated outpatient service of chronic diseases.

    Methods

    From October to November 2023, using the typical sampling method and taking into account the principle of geographical balance, 18 community health service centers/township hospitals under 6 medical communities in Linping District of Hangzhou, Yuhuan City of Taizhou, Jiangshan City of Quzhou and Jiashan County of Jiaxing in Zhejiang Province were selected, and outpatients were intercepted at the outpatient waiting offices of corresponding institutions as the research objects. A self-designed questionnaire was used to investigate the patients' evaluation of integrated outpatient services for chronic diseases. The evaluation content involved three aspects: service category, service approach and team building.

    Results

    A total of 540 questionnaires were distributed and 510 valid questionnaires were recovered, with an effective recovery rate of 94.4 %. The overall score of patients' integrated outpatient service for chronic diseases was (4.4±0.5) points, and the scores of each service category were: pre-diagnosis service (4.4±0.5) points, in-diagnosis service (4.3±0.5) points, and post-diagnosis service (4.1±0.6) points. The average score of each item in the service approach dimension was ≥3.7 points, and the average score of each item in the service team building dimension was ≥3.9 points. The results of multiple linear regression analysis showed that factors such as age, education, monthly income, whether the overall medical services of the hospital could meet their own needs, and satisfaction with the hospital 's diagnosis and treatment environment would have an impact on the evaluation of the development of integrated outpatient clinics for chronic diseases (P<0.05) .

    Conclusion

    The current situation of integrated outpatient services for chronic diseases in county medical communities in Zhejiang Province is generally good, but there is still room for improvement in post-diagnosis services, service channels, and overall medical services. The primary medical and health institutions in Zhejiang Province should pay attention to the continuity of post-treatment services, strengthen the integrated outpatient service mode and team building of chronic diseases, promote the development of medical services in a diversified and high-quality direction, and enhance the residents' sense of medical experience.

    Conception and Satisfaction of Integration of Medicine and Prevention from Providers' Perspective
    WANG Zijing, GAO Junwen, LI Cancan, YAN Huosheng, BAI Zhongliang, XIAO Jincheng, HU Zhi
    2025, 28(13):  1655-1660.  DOI: 10.12114/j.issn.1007-9572.2023.0736
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    Background

    For a long time, "emphasizing medicine over prevention" has fragmented China's medical and health service system, making it difficult for residents to obtain comprehensive, coordinated, high-quality and efficient health services. The integration of medicine and prevention plays an essential role in enhancing the continuity and coordination of medical and health services and improving the health of residents. As the providers of the integration of medicine and prevention services, the enthusiasm and initiative of medical staff directly affect the integration of medicine and prevention services.

    Objective

    To explore the current status and problems during the integration of medicine and prevention from the perspective of medical and public health service providers and to put forward appropriate countermeasures.

    Methods

    The data for this study was collected from a survey on the integration of medicine and prevention conducted in Anhui Province from July to August 2021, which combined typical sampling and stratified sampling methods, taking into account both representativeness and regional distribution. One county (district) was selected from the northern, central, and southern parts of Anhui Province for the survey. Based on the review of domestic and foreign literature and relevant policy documents, in consideration of the characteristics of the integration of medicine and prevention, the research team, after discussion and expert validation, developed a self-designed questionnaire for medical staff on the integration of medicine and prevention. The questionnaire mainly includes the basic information of the respondents, their cognition of the integration of medicine and prevention, the implementation and satisfaction of the integration of medicine and prevention. Binary Logistic regression analysis was used to explore the influencing factors of medical staff's satisfaction with the integration of medicine and prevention.

    Results

    71.2% of medical staff expressed understanding of the integration of medicine and prevention, 18.6% expressed very good understanding, 50.4% considered the integration of medicine and prevention very important, and 48.5% considered it necessary. The primary way to provide services of integration of medicine and prevention was to guide healthy lifestyles, which accounted for 92.0% of the total, 83.3% of the total for education on health knowledge, and 84.1% for guidance on the rational use of medication. The main factors that affected the implementation of the integration of medicine and prevention included financial support, lack of human resources, lack of incentive mechanisms, etc. The satisfaction score of medical staff with the integration of medicine and prevention was (4.02±0.78). The regression results showed that career development, salary, and work pressure significantly affected overall satisfaction with the integration of medicine and prevention (P<0.05) .

    Conclusion

    This paper found that there are insufficients of the integration of medicine and prevention concerning service providing scope, ability, and guarantee mechanism. Therefore, to better provide residents with a high-quality integration of medicine and prevention, further expansion of the ways of service providing, optimizing the capacity and quality of the service team, and improving the guarantee mechanism are suggested.

    Current Situation and Obstacles of Integrated Services for Chronic Diseases Provided by Family Doctor Team: a Qualitative Research
    ZHAO Linlin, LUO Qi, HU Qinghua, CHEN Xiaolei, DU Juan, SHAO Shuang
    2025, 28(13):  1661-1667.  DOI: 10.12114/j.issn.1007-9572.2024.0151
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    Background

    The integration of medical care and prevention is an important measure for the implementation of the Healthy China Strategy. Family doctor teams as the mainstay and chronic disease management as the entry point are important tools for the implementation of the medical and preventive integration in primary health institutions.

    Objective

    To understand the current situation and obstacles of the integration of medicine and prevention in chronic disease management in Beijing urban areas, so as to provide a basis for decision-making on sustainable development of the medical and preventive integration services.

    Methods

    From December 2023 to February 2024, the purposive sampling was used to invite 20 participants, including the members of the family doctor teams and primary care managers working on the the medical and preventive integration and the chronic disease management in 12 primary health institutions in the urban area of Beijing, to conducted semi-structured interviews focus on the content, division of labour, resource allocation, and existing problems of above services. Thematic analysis was used to analyse and generalise the interview data.

    Results

    Although the primary health institutions had explored a variety of service modalities to promote the implementation of the integration of medical care and prevention. The qualitative research showed that the main body of the current service was still the general practitioner and the community nurse, and continued the kernel of the chronic disease management service, with the content of the service yet to be innovated, and the service process of pre-consultation, consultation, and post-consultation yet to be promoted. In terms of the operating environment, there were insufficient members of the family medicine team, heavy workload, emphasis on "quantity" rather than "quality" in assessment and evaluation, "information silos", lack of top-level design, and lack of a special funding mechanism. The phenomenon of "medical and prevention fragmentation" is obvious, with the existence of "two lines" of the management systems, "two disconnections" between the main bodies, and regional dispersion of work areas of the medical and preventive integration.

    Conclusion

    Due to insufficient resources allocation and optimisation of the operation mode, it's necessary to strengthen talent training, reinforce medical insurance support, accelerate information sharing within the region, improve assessment and evaluation mechanisms, as well as strengthen the top-level design, clarify the service pathway, implement community functions, and form a replicable and scalable integrated service model with the participation of the government, community, hospitals and patients.

    Review & Perspectives
    Research Progress of Annexin A1 in Respiratory Diseases
    TAN Huihui, MAO Wei, YANG Zihan
    2025, 28(13):  1668-1673.  DOI: 10.12114/j.issn.1007-9572.2024.0154
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    Annexin A1 (ANXA1) is a potent anti-inflammatory protein, and research progress regarding its role in respiratory diseases has increasingly attracted attention. Research indicates that ANXA1 may participate in the pathophysiological process of respiratory diseases by regulating inflammatory response, clearing oxidative stress substances, and influencing cell apoptosis. However, there is currently a lack of effective integration in the research on ANXA1's involvement in the aforementioned disease processes. This article systematically and comprehensively summarizes the effects of ANXA1 on chronic obstructive pulmonary disease (COPD), asthma, pulmonary fibrosis, lung ischemia-reperfusion injury and lung cancer by reviewing relevant literature from recent years. It explores the mechanisms by which ANXA1 is involved in the occurrence and progression of these diseases. Research shows that ANXA1 exerts anti-inflammatory effects by regulating various inflammatory signaling pathways, participating in the inhibition of leukocyte migration, adhesion, and neutrophil apoptosis, suppressing airway hyperreactivity in asthma, alleviating pulmonary inflammation in COPD, and improving pulmonary fibrosis. In addition, ANXA1 also affects the proliferation, metastasis, and invasion of tumor cells. This article can provide a reference for the treatment of ANXA1 in respiratory diseases and serve as a guide for further in-depth research.

    Application of Internet of Things Technology in Primary-Level Pulmonary Function Testing and Management
    2025, 28(13):  1674-1675.  DOI: 10.12114/j.issn.1007-9572.2023.0682
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    Case Study in Public Health
    Technology Enabled Comprehensive Supervision of Medical Institutions: a Case Study of Shenzhen "Intelligent Health Supervision"
    XU Hanyi, XING Hejuan, MAO Xiangyun, ZHENG Shiqun, TIAN Qiannan, ZHANG Yi, CHEN Kaiyuan
    2025, 28(13):  1676-1680.  DOI: 10.12114/j.issn.1007-9572.2024.0683
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    With the rapid development of the healthcare industry and the increasing complexity of the regulatory environment, the traditional model of comprehensive supervision of medical institutions is facing challenges and needs to be innovated. The purpose of this paper is to explore the innovative path and mode of technology-enabled comprehensive supervision of medical institutions, and take Shenzhen "Intelligent Health Supervision" comprehensive supervision platform as the object of study, analyze its construction logic, technical architecture, functional modules and application effects. This study adopts the methods of literature review and case analysis, and analyzes the advantages and potentials of technology-enabled comprehensive supervision of medical institutions by combining with the actual application of Shenzhen "Smart Health Supervision" platform. Through the construction of the "Intelligent Health Supervision" comprehensive supervision information platform, Shenzhen has realized the whole process of dynamic supervision of medical personnel, medical behaviors, and medical institutions, and explored a set of intelligent, precise, and rigorous comprehensive supervision system for healthcare.