The content of this article came from "the Second Shanghai General Practitioners (GPs) Forum" hosted by Shanghai Physicians Association, General Practitioners Division of Shanghai Physicians Association, Shanghai, China, on July 22, 2022, and mainly included four sections as follow: the Role of Primary Medical Care in Integrating Medical Treatment, Constructing General Medical Sciences as National Key Clinical Specialty, Trends in the Development of Primary Health in Shanghai, and Embrace Change, Become Better and Stronger. Among them, the Role of Primary Medical Care in Integrating Medical Treatment illustrated the concept and connotation of "integrated medical treatment" from 3 dimensions: the degree of integration, the stratum of integration, and the direction of integration, and gave a detailed introduction to the realization pathway of integrated medical treatment at 5 levels: the system, management, payment, the service model, and the application of technology; based on the analysis of the common characteristics of primary care and integrated medical care, it illustrated the booster role of primary care in integrating medical treatment at the above 5 levels. From the important role of general practice departments in health care reform and meeting the needs of resident health services, Constructing General Medical Sciences as National Key Clinical Specialty illustrated the need to create a general practice department as a state key clinical specialty, and believed that creating a key clinical specialty need to do the following: creating a high-level of general practice department status, advancing the construction and development of talents in general practice, enhancing the regional collaborative capacity of general practice disciplines, and forming the characteristics of the full range of full cycle health care specialists, thereby promoting the scientific research and innovation development of general practice medicine. Trends in the Development of Primary Health in Shanghai affirmed the contributions of primary health to urban health development, and in the context of "big health", further focused efforts were proposed to promote healthy aging and achieve birth population promotion; the development trend of primary health in Shanghai lay in innovation, while innovation in high-quality development efforts of primary health required GPs as both enablers and leaders to create new models of health services. Embrace Change, Become Better and Stronger argued that the current "weakness" of community health services, was not the hardware or staffing deficit at the beginning of development, but was embodied in the construction of general disciplines. Working staff in the field of general practice should take the initiative to face and accept current changes from the national health strategy, in health needs, medical models, and their own development/management, carry out active health, cope with the coexistence of multiple diseases, strengthen the general and special combination, and focus on service evaluation from the perspective of consumers to assist the discipline construction of general practice medicine.