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Dialysis Duration of Death Patients Who Underwent Continuous Ambulatory Peritoneal Dialysis During Lifetime and Correlation Factor Analysis
- WANG Cheng-yu, LUO Yu-zhen, HUANG Yu-ming, LIAO Yun-hua
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2016, 19(36):
4447-4450.
DOI: 10.3969/j.issn.1007-9572.2016.36.009
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Objective To analyze the difference of dialysis duration between death patients with dabetic nephropathy and death patients with non-diabetic nephropathy who underwent continuous ambulatory peritoneal dialysis (CAPD) during lifetime,and to analyze the correlated factors of dialysis duration among them.Methods A total of 43 death patients with end stage renal disease (ESRD) who underwent CAPD during lifetime in the First Affiliated Hospital of Guangxi Medical University from 2006 to 2014 were selected as study subjects.According to the primary disease,the patients were divided into diabetic nephropathy group (10 cases) and non-diabetic nephropathy group (33 cases).Clinical data including sex,age at the beginning of CAPD,dialysis duration,systolic blood pressure,diastolic blood pressure,pulse,height,degree of weight of lower limbs,degree of edema of lower limbs,levels of hemoglobin (Hb),C-reactive protein (CRP),serum albumin (Alb),potassium,calcium,phosphorus,blood urea nitrogen (BUN),creatinine (Cr),intact parathyroid hormone (iPTH),total cholesterol (TC),three acyl glycerin (TG),high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),fasting blood glucose,ultrafiltration volume,the 4 h dialysate-to-plasma ratio (D/P) of creatinine,estimated glomerular filtration rate (eGFR),24 h urine volume,total liquid output (24 h ultrafiltration volume +24 h urine volume),peritoneal urea clearance (peritoneal KT/V),and total urea clearance (total KT/V) of patients at the beginning of CAPD were analyzed.Results There was no significant difference in sex,age,systolic blood pressure,diastolic blood pressure,pulse,height,degree of edemaof lower limbs,Hb,CRP,Alb,potassium,calcium,phosphorus,BUN,iPTH,TC,TG,HDL-C,LDL-C,ultrafiltration volume,D/P,eGFR,24 h urine volume,total content,peritoneal KT/V,and total KT/V between non-diabetic nephropathy group and diabetic nephropathy group (P>0.05).Dialysis duration 〔(39.1±24.4) months vs.(20.7±15.8) months〕and the level of Cr in non-diabetic nephropathy group were higher than those in diabetic nephropathy group (P<0.05).Weight and fasting blood glucose level in non-diabetic nephropathy group were lower than those in diabetic nephropathy group (P<0.05).Dialysis duration was not linear correlated with sex,age,systolic blood pressure,diastolic blood pressure,height,weight,degree of edema of lower limbs,Hb,CRP,Alb,potassium,calcium,phosphorus,BUN,Cr,iPTH,TC,TG,LDL-C,fasting blood glucose,ultrafiltration volume,and D/P (P>0.05).Dialysis duration was negatively correlated with pulse,and positively correlated with HDL-C,eGFR,24 h urine volume,total liquid output,peritoneal KT/V and total KT/V (P<0.05).Conclusion The dialysis duration of diabetic nephropathy patients receiving CAPD was shorter than that of non-diabetic nephropathy patients receiving CAPD.Pulse,HDL-C,eGFR,24 h urine volume,total liquid output,peritoneal Kt/V and total KT/V are correlated with dialysis duration.