Chinese General Practice ›› 2024, Vol. 27 ›› Issue (05): 552-556.DOI: 10.12114/j.issn.1007-9572.2023.0201
• Original Research • Previous Articles
Received:
2023-02-15
Revised:
2023-06-09
Published:
2024-02-15
Online:
2023-11-21
Contact:
ZHANG Hairong
通讯作者:
张海蓉
作者简介:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0201
组别 | 例数 | 性别[例(%)] | 年龄(岁) | 吸烟史[例(%)] | 病因[例(%)] | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
男 | 女 | 病毒性肝炎 | 酒精性 | 自身免疫性 | 血吸虫 | 药物性 | 两种及以上病因 | 病因不明 | ||||
出血组 | 127 | 87(68.5) | 40(31.5) | 53.8±11.5 | 49(38.6) | 69(54.3) | 22(17.3) | 7(5.5) | 1(0.8) | 1(0.8) | 3(2.4) | 24(18.9) |
非出血组 | 152 | 103(67.8) | 49(32.2) | 54.4±13.0 | 65(42.8) | 87(57.2) | 17(11.2) | 12(7.9) | 0 | 0 | 17(11.2) | 19(12.5) |
χ2(t)值 | <0.001 | 0.401a | 0.178 | 14.290 | ||||||||
P值 | 0.997 | 0.692 | 0.673 | 0.027 | ||||||||
组别 | 血管部位[例(%)] | 腹腔手术史[例(%)] | Child-Pugh分级[例(%)] | |||||||||
PV | SMV | SV | PV+SMV | PV+SV | PV+SMV+SV | TIPS | 内镜止血 | 脾栓塞术 | A级 | B级 | C级 | |
出血组 | 54(42.5) | 16(12.6) | 8(6.3) | 34(26.8) | 6(4.7) | 9(7.1) | 9(7.1) | 21(16.5) | 5(3.9) | 22(17.3) | 70(55.1) | 35(27.6) |
非出血组 | 94(61.8) | 13(8.6) | 8(5.3) | 21(13.8) | 11(7.2) | 5(3.3) | 23(15.1) | 11(7.2) | 6(3.9) | 31(20.4) | 76(50.0) | 45(29.6) |
χ2(t)值 | 14.685 | 9.048 | 2.205 | |||||||||
P值 | 0.012 | 0.011 | 0.332 |
Table 1 Comparison of general information between the bleeding group and non-bleeding group
组别 | 例数 | 性别[例(%)] | 年龄(岁) | 吸烟史[例(%)] | 病因[例(%)] | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
男 | 女 | 病毒性肝炎 | 酒精性 | 自身免疫性 | 血吸虫 | 药物性 | 两种及以上病因 | 病因不明 | ||||
出血组 | 127 | 87(68.5) | 40(31.5) | 53.8±11.5 | 49(38.6) | 69(54.3) | 22(17.3) | 7(5.5) | 1(0.8) | 1(0.8) | 3(2.4) | 24(18.9) |
非出血组 | 152 | 103(67.8) | 49(32.2) | 54.4±13.0 | 65(42.8) | 87(57.2) | 17(11.2) | 12(7.9) | 0 | 0 | 17(11.2) | 19(12.5) |
χ2(t)值 | <0.001 | 0.401a | 0.178 | 14.290 | ||||||||
P值 | 0.997 | 0.692 | 0.673 | 0.027 | ||||||||
组别 | 血管部位[例(%)] | 腹腔手术史[例(%)] | Child-Pugh分级[例(%)] | |||||||||
PV | SMV | SV | PV+SMV | PV+SV | PV+SMV+SV | TIPS | 内镜止血 | 脾栓塞术 | A级 | B级 | C级 | |
出血组 | 54(42.5) | 16(12.6) | 8(6.3) | 34(26.8) | 6(4.7) | 9(7.1) | 9(7.1) | 21(16.5) | 5(3.9) | 22(17.3) | 70(55.1) | 35(27.6) |
非出血组 | 94(61.8) | 13(8.6) | 8(5.3) | 21(13.8) | 11(7.2) | 5(3.3) | 23(15.1) | 11(7.2) | 6(3.9) | 31(20.4) | 76(50.0) | 45(29.6) |
χ2(t)值 | 14.685 | 9.048 | 2.205 | |||||||||
P值 | 0.012 | 0.011 | 0.332 |
组别 | 例数 | 腹痛[例(%)] | 发热[例(%)] | 黄疸[例(%)] | 腹水[例(%)] | 肺部感染[例(%)] | 胸腔积液[例(%)] | 胆石症[例(%)] | 肝性脑病[例(%)] | 脾梗死[例(%)] | 肠梗阻[例(%)] | VPV [M(P25,P75),cm/s] |
---|---|---|---|---|---|---|---|---|---|---|---|---|
出血组 | 127 | 22(17.3) | 6(4.7) | 1(0.8) | 87(68.5) | 51(40.2) | 43(33.9) | 24(18.9) | 5(3.9) | 3(2.6) | 1(0.8) | 18.00(15.97,22.25) |
非出血组 | 152 | 39(25.7) | 9(5.9) | 11(7.2) | 92(60.5) | 50(32.9) | 43(28.3) | 19(12.5) | 10(6.6) | 6(4.3) | 0 | 18.00(15.00,18.27) |
检验统计量值 | 2.531 | 0.040 | 5.513 | 1.584 | 2.065 | 1.059 | 1.709 | 0.501 | 0.164 | 0.008 | -1.517a | |
P值 | 0.112 | 0.841 | 0.019 | 0.208 | 0.724 | 0.589 | 0.191 | 0.479 | 0.686 | 0.928 | 0.322 | |
组别 | DMPV[M(P25,P75),cm] | 脾大[例(%)] | GOV [例(%)] | 侧支循环开放[例(%)] | 门静脉海绵样变性[例(%)] | WBC (×109/L) | Hb (g/L) | HCT (%) | PLT [M(P25,P75),×109/L] | TBiL [M(P25,P75),μmol/L] | ||
出血组 | 1.60(1.40,1.70) | 114(89.8) | 91(71.7) | 54(42.5) | 5(3.9) | 4.83±3.71 | 84.38±23.53 | 26.23±6.56 | 67.00(49.50,92.00) | 21.20(13.35,32.15) | ||
非出血组 | 1.40(1.30,1.60) | 132(86.8) | 83(54.6) | 69(45.4) | 13(8.6) | 3.54±2.07 | 105.40±29.77 | 32.47±7.79 | 68.50(47.50,102.50) | 23.10(15.57,39.90) | ||
检验统计量值 | -2.338a | 1.180 | 7.857 | 0.130 | 1.737 | -3.424b | 6.454b | 7.145b | 1.239a | 2.956a | ||
P值 | 0.004 | 0.277 | 0.005 | 0.718 | 0.187 | <0.001 | <0.001 | <0.001 | 0.946 | 0.024 | ||
组别 | Scr[M(P25,P75),μmol/L] | ALT [M(P25,P75),U/L] | AST [M(P25,P75),U/L] | ALB [M(P25,P75),g/L] | BUN[M(P25,P75),mmol/L] | D-D[M(P25,P75),mg/L] | FIB[M(P25,P75),g/L] | |||||
出血组 | 76.00(66.77,92.03) | 28.00(20.05,41.15) | 35.35(26.25,49.00) | 30.90(26.40,34.60) | 5.05(3.91,7.91) | 3.27(1.37,5.96) | 1.62(1.39,2.09) | |||||
非出血组 | 73.30(61.55,86.05) | 26.90(19.23,37.00) | 37.35(27.50,52.27) | 31.10(27.55,35.30) | 4.54(3.49,6.21) | 2.52(0.82,5.29) | 1.90(1.48,2.45) | |||||
检验统计量值 | -1.569a | -1.531a | -0.664a | 0.857a | -2.523a | -0.698a | 2.601a | |||||
P值 | 0.078 | 0.443 | 0.288 | 0.350 | 0.015 | 0.257 | 0.013 |
Table 2 Comparison of symptoms,complications,laboratory and imaging findings between the bleeding group and non-bleeding group
组别 | 例数 | 腹痛[例(%)] | 发热[例(%)] | 黄疸[例(%)] | 腹水[例(%)] | 肺部感染[例(%)] | 胸腔积液[例(%)] | 胆石症[例(%)] | 肝性脑病[例(%)] | 脾梗死[例(%)] | 肠梗阻[例(%)] | VPV [M(P25,P75),cm/s] |
---|---|---|---|---|---|---|---|---|---|---|---|---|
出血组 | 127 | 22(17.3) | 6(4.7) | 1(0.8) | 87(68.5) | 51(40.2) | 43(33.9) | 24(18.9) | 5(3.9) | 3(2.6) | 1(0.8) | 18.00(15.97,22.25) |
非出血组 | 152 | 39(25.7) | 9(5.9) | 11(7.2) | 92(60.5) | 50(32.9) | 43(28.3) | 19(12.5) | 10(6.6) | 6(4.3) | 0 | 18.00(15.00,18.27) |
检验统计量值 | 2.531 | 0.040 | 5.513 | 1.584 | 2.065 | 1.059 | 1.709 | 0.501 | 0.164 | 0.008 | -1.517a | |
P值 | 0.112 | 0.841 | 0.019 | 0.208 | 0.724 | 0.589 | 0.191 | 0.479 | 0.686 | 0.928 | 0.322 | |
组别 | DMPV[M(P25,P75),cm] | 脾大[例(%)] | GOV [例(%)] | 侧支循环开放[例(%)] | 门静脉海绵样变性[例(%)] | WBC (×109/L) | Hb (g/L) | HCT (%) | PLT [M(P25,P75),×109/L] | TBiL [M(P25,P75),μmol/L] | ||
出血组 | 1.60(1.40,1.70) | 114(89.8) | 91(71.7) | 54(42.5) | 5(3.9) | 4.83±3.71 | 84.38±23.53 | 26.23±6.56 | 67.00(49.50,92.00) | 21.20(13.35,32.15) | ||
非出血组 | 1.40(1.30,1.60) | 132(86.8) | 83(54.6) | 69(45.4) | 13(8.6) | 3.54±2.07 | 105.40±29.77 | 32.47±7.79 | 68.50(47.50,102.50) | 23.10(15.57,39.90) | ||
检验统计量值 | -2.338a | 1.180 | 7.857 | 0.130 | 1.737 | -3.424b | 6.454b | 7.145b | 1.239a | 2.956a | ||
P值 | 0.004 | 0.277 | 0.005 | 0.718 | 0.187 | <0.001 | <0.001 | <0.001 | 0.946 | 0.024 | ||
组别 | Scr[M(P25,P75),μmol/L] | ALT [M(P25,P75),U/L] | AST [M(P25,P75),U/L] | ALB [M(P25,P75),g/L] | BUN[M(P25,P75),mmol/L] | D-D[M(P25,P75),mg/L] | FIB[M(P25,P75),g/L] | |||||
出血组 | 76.00(66.77,92.03) | 28.00(20.05,41.15) | 35.35(26.25,49.00) | 30.90(26.40,34.60) | 5.05(3.91,7.91) | 3.27(1.37,5.96) | 1.62(1.39,2.09) | |||||
非出血组 | 73.30(61.55,86.05) | 26.90(19.23,37.00) | 37.35(27.50,52.27) | 31.10(27.55,35.30) | 4.54(3.49,6.21) | 2.52(0.82,5.29) | 1.90(1.48,2.45) | |||||
检验统计量值 | -1.569a | -1.531a | -0.664a | 0.857a | -2.523a | -0.698a | 2.601a | |||||
P值 | 0.078 | 0.443 | 0.288 | 0.350 | 0.015 | 0.257 | 0.013 |
变量 | B值 | SE | Wald χ2值 | P值 | OR值 | 95%CI |
---|---|---|---|---|---|---|
WBC | 0.938 | 0.398 | 2.358 | 0.018 | 2.555 | 1.318~6.542 |
HCT | -0.672 | 0.329 | -2.042 | 0.041 | 0.511 | 0.247~0.925 |
FIB | -2.462 | 1.207 | -2.040 | 0.041 | 0.085 | 0.005~0.661 |
SMV | 3.328 | 1.690 | 1.970 | 0.049 | 27.873 | 1.452~1 335.715 |
常量 | 7.555 | 4.377 | 1.726 | 0.084 | 1 910.605 | 0.779~35 867 824.590 |
Table 3 Multivariate Logistic regression analysis of the influencing factors of gastrointestinal bleeding in cirrhotic patients with PVT
变量 | B值 | SE | Wald χ2值 | P值 | OR值 | 95%CI |
---|---|---|---|---|---|---|
WBC | 0.938 | 0.398 | 2.358 | 0.018 | 2.555 | 1.318~6.542 |
HCT | -0.672 | 0.329 | -2.042 | 0.041 | 0.511 | 0.247~0.925 |
FIB | -2.462 | 1.207 | -2.040 | 0.041 | 0.085 | 0.005~0.661 |
SMV | 3.328 | 1.690 | 1.970 | 0.049 | 27.873 | 1.452~1 335.715 |
常量 | 7.555 | 4.377 | 1.726 | 0.084 | 1 910.605 | 0.779~35 867 824.590 |
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