Chinese General Practice ›› 2024, Vol. 27 ›› Issue (03): 328-334.DOI: 10.12114/j.issn.1007-9572.2023.0291
Special Issue: 肿瘤最新文章合集
• Original Research • Previous Articles Next Articles
Received:
2023-04-03
Revised:
2023-07-15
Published:
2024-01-20
Online:
2023-10-23
Contact:
HU Xin, JIANG Wei
通讯作者:
胡欣, 江伟
作者简介:
基金资助:
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URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2023.0291
组别 | 例数 | 年龄(岁) | 性别(男/女) | 病程(年) | 受教育年限(年) | GDS-15评分(分) | GAD-7评分(分) | PSQI评分(分) |
---|---|---|---|---|---|---|---|---|
轻度失眠组 | 32 | 72.4±5.1 | 14/18 | 9.8±4.3 | 12.0±3.2 | 6.7±1.8 | 7.3±1.4 | 8.3±1.3 |
中度失眠组 | 38 | 72.2±4.5 | 18/20 | 10.1±4.5 | 13.4±3.4 | 6.9±2.1 | 7.7±1.8 | 13.3±1.3a |
重度失眠组 | 35 | 73.2±5.0 | 16/19 | 10.3±5.0 | 12.2±3.4 | 7.1±1.9 | 7.9±2.1 | 18.3±1.6ab |
F(χ2)值 | 0.483 | 0.092c | 0.174 | 1.873 | 0.372 | 0.925 | 446.656 | |
P值 | 0.619 | 0.955 | 0.841 | 0.159 | 0.691 | 0.400 | <0.001 |
Table 1 Comparison of general data and PSQI score in the three groups
组别 | 例数 | 年龄(岁) | 性别(男/女) | 病程(年) | 受教育年限(年) | GDS-15评分(分) | GAD-7评分(分) | PSQI评分(分) |
---|---|---|---|---|---|---|---|---|
轻度失眠组 | 32 | 72.4±5.1 | 14/18 | 9.8±4.3 | 12.0±3.2 | 6.7±1.8 | 7.3±1.4 | 8.3±1.3 |
中度失眠组 | 38 | 72.2±4.5 | 18/20 | 10.1±4.5 | 13.4±3.4 | 6.9±2.1 | 7.7±1.8 | 13.3±1.3a |
重度失眠组 | 35 | 73.2±5.0 | 16/19 | 10.3±5.0 | 12.2±3.4 | 7.1±1.9 | 7.9±2.1 | 18.3±1.6ab |
F(χ2)值 | 0.483 | 0.092c | 0.174 | 1.873 | 0.372 | 0.925 | 446.656 | |
P值 | 0.619 | 0.955 | 0.841 | 0.159 | 0.691 | 0.400 | <0.001 |
组别 | 例数 | 总睡眠时间(min) | 睡眠潜伏期(min) | 睡眠效率(%) | 觉醒次数(次) |
---|---|---|---|---|---|
轻度失眠组 | 32 | 375.16±62.45 | 28.44±10.18 | 71.25±16.53 | 9.34±3.31 |
中度失眠组 | 38 | 354.27±78.33 | 36.53±14.49a | 63.48±13.19a | 11.63±5.05 |
重度失眠组 | 35 | 328.33±65.34a | 45.57±18.96ab | 54.37±10.25ab | 14.37±6.50ab |
F值 | 3.826 | 10.829 | 13.220 | 7.968 | |
P值 | 0.025 | <0.001 | <0.001 | 0.001 |
Table 2 Comparison of sleep parameters recorded by PPG in the three groups
组别 | 例数 | 总睡眠时间(min) | 睡眠潜伏期(min) | 睡眠效率(%) | 觉醒次数(次) |
---|---|---|---|---|---|
轻度失眠组 | 32 | 375.16±62.45 | 28.44±10.18 | 71.25±16.53 | 9.34±3.31 |
中度失眠组 | 38 | 354.27±78.33 | 36.53±14.49a | 63.48±13.19a | 11.63±5.05 |
重度失眠组 | 35 | 328.33±65.34a | 45.57±18.96ab | 54.37±10.25ab | 14.37±6.50ab |
F值 | 3.826 | 10.829 | 13.220 | 7.968 | |
P值 | 0.025 | <0.001 | <0.001 | 0.001 |
组别 | 例数 | MMSE评分 | MoCA评分 |
---|---|---|---|
轻度失眠组 | 32 | 27.19±1.87 | 25.91±2.02 |
中度失眠组 | 38 | 25.82±2.15a | 24.47±2.01a |
重度失眠组 | 35 | 24.37±1.77ab | 23.11±1.89ab |
F值 | 17.512 | 16.711 | |
P值 | <0.001 | <0.001 |
Table 3 Comparison of cognitive functions in the three groups
组别 | 例数 | MMSE评分 | MoCA评分 |
---|---|---|---|
轻度失眠组 | 32 | 27.19±1.87 | 25.91±2.02 |
中度失眠组 | 38 | 25.82±2.15a | 24.47±2.01a |
重度失眠组 | 35 | 24.37±1.77ab | 23.11±1.89ab |
F值 | 17.512 | 16.711 | |
P值 | <0.001 | <0.001 |
组别 | 例数 | 25(OH)D3(ng/ml) | TNF-α(pg/ml) |
---|---|---|---|
轻度失眠组 | 32 | 53.29±16.76 | 428.63±41.44 |
中度失眠组 | 38 | 41.61±12.33a | 494.38±50.37a |
重度失眠组 | 35 | 32.09±10.46ab | 535.82±58.29ab |
F值 | 21.242 | 37.752 | |
P值 | <0.001 | <0.001 |
Table 4 Comparison of serum 25(OH)D3 and TNF-α levels among the three groups
组别 | 例数 | 25(OH)D3(ng/ml) | TNF-α(pg/ml) |
---|---|---|---|
轻度失眠组 | 32 | 53.29±16.76 | 428.63±41.44 |
中度失眠组 | 38 | 41.61±12.33a | 494.38±50.37a |
重度失眠组 | 35 | 32.09±10.46ab | 535.82±58.29ab |
F值 | 21.242 | 37.752 | |
P值 | <0.001 | <0.001 |
指标 | MMSE评分 | MoCA评分 | ||
---|---|---|---|---|
rs值 | P值 | rs值 | P值 | |
失眠严重程度 | -0.509 | <0.001 | -0.522 | <0.001 |
总睡眠时间 | 0.227 | 0.020 | 0.230 | 0.018 |
睡眠潜伏期 | -0.532 | <0.001 | -0.536 | <0.001 |
睡眠效率 | 0.263 | 0.007 | 0.258 | 0.008 |
觉醒次数 | -0.374 | <0.001 | -0.386 | <0.001 |
25(OH)D3 | 0.535 | <0.001 | 0.514 | <0.001 |
TNF-α | -0.495 | <0.001 | -0.483 | <0.001 |
Table 5 Correlation analysis of cognitive functions with insomnia severity,sleep and serologic indexes in elderly patients with chronic insomnia
指标 | MMSE评分 | MoCA评分 | ||
---|---|---|---|---|
rs值 | P值 | rs值 | P值 | |
失眠严重程度 | -0.509 | <0.001 | -0.522 | <0.001 |
总睡眠时间 | 0.227 | 0.020 | 0.230 | 0.018 |
睡眠潜伏期 | -0.532 | <0.001 | -0.536 | <0.001 |
睡眠效率 | 0.263 | 0.007 | 0.258 | 0.008 |
觉醒次数 | -0.374 | <0.001 | -0.386 | <0.001 |
25(OH)D3 | 0.535 | <0.001 | 0.514 | <0.001 |
TNF-α | -0.495 | <0.001 | -0.483 | <0.001 |
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