Advances in Magnetic Resonance Imaging Technology Applied to Human Brain Glymphatic System

doi:10.12114/j.issn.1007-9572.2023.0380

Chinese General Practice ›› 2024, Vol. 27 ›› Issue (26): 3314-3319.DOI: 10.12114/j.issn.1007-9572.2023.0380

Special Issue: 脑健康最新研究合辑

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Advances in Magnetic Resonance Imaging Technology Applied to Human Brain Glymphatic System

1.School of Medical and Life Science, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
2.School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
3.Department of Radiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China
4.Department of Neurology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, China

Received:2023-05-15 Revised:2023-07-10 Published:2024-09-15 Online:2024-06-14
Contact: JIN Shuoguo, YIN Haiyan

应用于人脑胶质淋巴系统的磁共振成像技术研究进展

1.611137　四川省成都市，成都中医药大学医学与生命科学学院
2.611137　四川省成都市，成都中医药大学针灸推拿学院
3.610072　四川省成都市，成都中医药大学附属医院放射科
4.610072　四川省成都市，成都中医药大学附属医院神经内科

通讯作者: 金硕果, 尹海燕
作者简介:
作者贡献：
陈泽然负责文章的构思与设计、资料收集整理、撰写论文；黄梦颖、曾利川协助资料收集及勘误；金硕果、尹海燕负责最终版本修订，对论文负责。所有作者确认论文终稿。
基金资助:
国家自然科学基金青年科学基金(82004342); 成都中医药大学2021年杏林学者学科人才科研提升计划项目(QJRC2021006); 成都中医药大学附属医院"百人计划"科研项目(21-Q21)

Abstract

Abstract:

The glial lymphatic system is a recently discovered anatomical structure in the field of neuroscience, with functions such as regulation of interstitial fluid movement, waste removal and potentially brain immunity, playing an important role in physiology and pathology of the central nervous system. With the development of imaging technology, more and more magnetic resonance imaging (MRI) techniques have been applied to the study of the glial lymphatic system of the human brain. Currently, the commonly used imaging techniques include dynamic contrast-enhanced MRI, diffusion tensor image analysis along the perivascular space, and novel multimodal ultra-fast magnetic resonance techniques, etc. This article summarizes and reviews the application of these techniques in the brain glymphatic system, in order to provide a reference for the imaging study of the glymphatic system.

Key words: Glymphatic system, Central nervous system, Lymphatic system, Magnetic resonance imaging, Dynamic contrast-enhanced magnetic resonance imaging, Diffusion tensor imaging-analysis technique along the perivascular space, Ultra-fast magnetic resonance imaging

摘要：

胶质淋巴系统是神经科学领域近期发现的解剖结构，具有调节间质液运动、废物清除和潜在的大脑免疫等功能，在中枢神经系统的生理及病理中发挥重要作用。随着影像学技术的发展，越来越多的磁共振成像（MRI）技术被应用于人脑胶质淋巴系统的研究，目前常用的MRI技术有动态对比增强磁共振成像技术、沿血管周围间隙扩散张量成像分析技术及新型多模态超快速磁共振技术等，本文就这些技术在脑胶质淋巴系统的应用现状进行汇总综述，以期为胶质淋巴系统的影像学研究提供参考。

关键词: 神经胶细胞类淋巴系统, 中枢神经系统, 淋巴系统, 磁共振成像, 动态对比增强磁共振, 沿血管周围间隙扩散张量成像分析, 超快速磁共振成像

CLC Number:

R 322.811

CHEN Zeran,HUANG Mengying,ZENG Lichuan, et al. Advances in Magnetic Resonance Imaging Technology Applied to Human Brain Glymphatic System[J]. Chinese General Practice, 2024, 27(26): 3314-3319. DOI: 10.12114/j.issn.1007-9572.2023.0380.
陈泽然,黄梦颖,曾利川等. 应用于人脑胶质淋巴系统的磁共振成像技术研究进展[J]. 中国全科医学, 2024, 27(26): 3314-3319. DOI: 10.12114/j.issn.1007-9572.2023.0380.

Figures/Tables 2

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Advances in Magnetic Resonance Imaging Technology Applied to Human Brain Glymphatic System

应用于人脑胶质淋巴系统的磁共振成像技术研究进展

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