Chinese General Practice ›› 2023, Vol. 26 ›› Issue (33): 4110-4117.DOI: 10.12114/j.issn.1007-9572.2023.0200

• Review & Perspectives • Previous Articles     Next Articles

Advances in Duration of Untreated Psychosis and Its Early Intervention

  

  1. 1. Department of Basic Nursing, School of Nursing, Harbin Medical University, Daqing 163319, China
    2. The Second Ward of Obstetrics Department of Daqing People's Hospital, Daqing 163000, China
  • Received:2023-02-14 Revised:2023-05-15 Published:2023-11-20 Online:2023-06-07
  • Contact: WANG Zhengjun

精神病未治期及其早期干预的研究进展

  

  1. 1.163319 黑龙江省大庆市,哈尔滨医科大学护理学院基础护理学部
    2.163000 黑龙江省大庆市,大庆人民医院产科二病区
  • 通讯作者: 王正君
  • 作者简介:
    作者贡献:张思宇负责文章的构思与设计、研究资料的收集与整理、论文撰写;周郁秋、杜晓慧负责论文修订、英文的修订;王正君负责文章的质量控制及审校、对文章整体负责,监督管理。
  • 基金资助:
    国家自然科学基金资助项目(72204068,72074063); 大庆市指导性科技计划项目(zdy-2021-86); 黑龙江省省属高等学校基本科研业务费基础研究项目(JFQN202103)

Abstract:

Mental illness usually involves a range of cognitive, behavioral, and affective symptoms associated with impaired occupational or social functioning. Duration of untreated psychosis (DUP) is considered as an important predictor and independent risk factor for the prognosis of patients with mental disorders, a longer DUP is associated with poor prognosis. Meanwhile, early intervention measures to shorten DUP have gradually attracted increasing attention from both domestic and international researchers. In this paper, the related studies on DUP were reviewed and analyzed, the concept, measurement tools, neurobiological mechanisms of DUP, the relationship between DUP and prognosis, and early intervention measures to shorten DUP were described, in order to provide ideas and reference for developing clinical intervention strategies for DUP.

Key words: Mental disorders, Schizophrenia, Duration of untreated psychosis, Early medical intervention, Prognosis, Review

摘要:

精神病通常涉及一系列与职业或社会功能受损有关的认知、行为和情感症状。未治期是影响精神病患者预后的重要预测因素和独立危险因素,较长的未治期与疾病不良预后相关,缩短未治期的早期干预措施也逐渐受到国内外研究者的关注。本文回顾分析了精神病未治期的相关研究,阐述了未治期的概念、测量工具、神经生物学机制、未治期与精神病预后的关系及缩短未治期的早期干预措施,为临床针对精神病未治期的相关干预策略提供思路和依据。

关键词: 精神障碍, 精神分裂症, 未治期, 早期医疗干预, 预后, 综述