Abstract:

Malignant hypertension is a common hypertensive emergency, which generally progresses rapidly, often affects important target organs such as the heart, brain, and kidney, leading to organ insufficiency. Malignant hypertension may develop serious complications, among which thrombotic microangiopathy is mainly characterized by impaired tissue and organ functions due to thrombosis in the microcirculation, with critical condition and poor prognosis generally. Pancreatic involvement in malignant hypertension is rare, whose prognosis may be extreme poor and mortality may be high due to insufficient understanding of it, and lack of clinical evidence on its early diagnosis and treatment. We reported the diagnosis and treatment of a case of acute pancreatic infarction caused by malignant hypertension, aiming at providing a reference for clinical practice.

Key words: Hypertension, malignant, Acute pancreatic infarction, Thrombotic microangiopathies, Case reports

摘要：

恶性高血压（MHT）是常见的高血压急症，病情一般进展较快，常累及心、脑、肾等重要靶器官，导致器官功能不全。血栓性微血管病（TMA）是MHT的严重并发症之一，以微循环中血栓形成导致组织器官功能受损为主要特点，大多病情危重，预后差。MHT靶器官损害中胰腺受累罕见，由于对其认识不足，临床缺乏早期诊断及治疗的经验，导致患者预后极差，病死率高。本文报道了1例MHT致急性胰腺梗死病例的诊断及治疗过程，以期为临床工作提供借鉴。

关键词: 高血压，恶性, 急性胰腺梗死, 血栓性微血管病, 病例报告