Chinese General Practice ›› 2022, Vol. 25 ›› Issue (03): 354-362.DOI: 10.12114/j.issn.1007-9572.2021.02.086
• Evidence-based Medicine • Previous Articles Next Articles
Urease Breath Test and Stool Antigen Test Diagnose Helicobacter Pylori Infection in Patients with Bleeding Peptic Ulcer:a Meta-analysis
1.Guangzhou University of Chinese Medicine,Guangzhou 510405,China
2.The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China
*Corresponding author:CHEN Bin,Professor,Chief physician;E-mail:ddwchen@qq.com
LIAO Guibin and GONG Jiaqian are co-first authors
Received:
2021-07-02
Revised:
2021-09-28
Published:
2022-01-20
Online:
2021-12-29
通讯作者:
陈斌
基金资助:
CLC Number:
LIAO Guibin, GONG Jiaqian, ZHAO Lina, HOU Jiangtao, ZHENG Hongming, LI Yiting, WU Yuan, CHEN Bin.
Urease Breath Test and Stool Antigen Test Diagnose Helicobacter Pylori Infection in Patients with Bleeding Peptic Ulcer:a Meta-analysis [J]. Chinese General Practice, 2022, 25(03): 354-362.
Add to citation manager EndNote|Ris|BibTeX
URL: https://www.chinagp.net/EN/10.12114/j.issn.1007-9572.2021.02.086
第一作者 | 发表时间(年) | 地区 | 样本量(例) | NSAIDs使用率〔n(%)〕 | H.pylori感染判定标准 | 是否纳入应用PPI或抗生素患者 | 平均取样时间 | H.pylori感染率〔n(%)〕 | 灵敏度(%) | 特异度(%) |
---|---|---|---|---|---|---|---|---|---|---|
TU[ | 1999 | 中国 | 77 | 0 | ①阳性或②阳性或③④⑥中至少有2项阳性 | 否 | <24 h | 77(100.0) | 93.5 | - |
LóPEZ PEÑAS[ | 2001 | 西班牙 | 32 | 18(56.3) | ②③④⑥中至少有2项阳性 | 否 | <24 h | 23(71.9) | 87.0 | 100.0 |
GRIÑó[ | 2001 | 西班牙 | 78 | 44(56.4) | ②阳性或④和⑥均阳性 | 是 | <24 h | 68(87.2) | 91.3 | 77.8 |
CHUNG[ | 2001 | 韩国 | 32 | 0 | ②③④⑥中至少有2项阳性 | 否 | <24 h | 32(100.0) | 100.0 | - |
CHUNG[ | 2001 | 韩国 | 32 | 0 | ②③④⑥中至少有2项阳性 | 否 | 第7天 | 32(100.0) | 90.6 | - |
WILDNER-CHRISTENSEN[ | 2002 | 丹麦 | 95 | 70(73.7) | ②阳性 | 否 | <24 h | 44(46.3) | 86.4 | 96.1 |
GRIÑó[ | 2003 | 西班牙 | 68 | 41(60.3) | ②阳性或③④⑥中至少有2项阳性 | 是 | - | 59(86.8) | 93.1 | 87.5 |
WINIARSKI[ | 2003 | 波兰 | 81 | - | ⑥阳性 | 否 | <24 h | 64(79.0) | 98.4 | 100.0 |
LIAO[ | 2003 | 中国 | 57 | 0 | ②③④中至少有2项阳性 | 否 | <24 h | 46(80.7) | 100.0 | 81.8 |
LO[ | 2005 | 中国 | 55 | 26(47.3) | ①阳性或②③④⑥中至少有3项阳性 | 否 | <24 h | 35(63.6) | 94.3 | 85.0 |
张厚德[ | 1997 | 中国 | 51 | - | ②和④均阳性 | - | <96 h | 42(82.4) | 73.8 | 100.0 |
林勇[ | 2004 | 中国 | 40 | - | ③和⑥均阳性 | 否 | - | 24(60.0) | 37.5 | 87.5 |
李舜[ | 2005 | 中国 | 31 | - | ②阳性 | 否 | - | 31(100.0) | 61.3 | - |
王醒[ | 2019 | 中国 | 116 | - | ②阳性 | 否 | 第5天 | 56(48.3) | 51.8 | 86.7 |
Table 1 Basic characteristics of the UBT aimed to detect H.pylori infection in patients with peptic ulcer bleeding
第一作者 | 发表时间(年) | 地区 | 样本量(例) | NSAIDs使用率〔n(%)〕 | H.pylori感染判定标准 | 是否纳入应用PPI或抗生素患者 | 平均取样时间 | H.pylori感染率〔n(%)〕 | 灵敏度(%) | 特异度(%) |
---|---|---|---|---|---|---|---|---|---|---|
TU[ | 1999 | 中国 | 77 | 0 | ①阳性或②阳性或③④⑥中至少有2项阳性 | 否 | <24 h | 77(100.0) | 93.5 | - |
LóPEZ PEÑAS[ | 2001 | 西班牙 | 32 | 18(56.3) | ②③④⑥中至少有2项阳性 | 否 | <24 h | 23(71.9) | 87.0 | 100.0 |
GRIÑó[ | 2001 | 西班牙 | 78 | 44(56.4) | ②阳性或④和⑥均阳性 | 是 | <24 h | 68(87.2) | 91.3 | 77.8 |
CHUNG[ | 2001 | 韩国 | 32 | 0 | ②③④⑥中至少有2项阳性 | 否 | <24 h | 32(100.0) | 100.0 | - |
CHUNG[ | 2001 | 韩国 | 32 | 0 | ②③④⑥中至少有2项阳性 | 否 | 第7天 | 32(100.0) | 90.6 | - |
WILDNER-CHRISTENSEN[ | 2002 | 丹麦 | 95 | 70(73.7) | ②阳性 | 否 | <24 h | 44(46.3) | 86.4 | 96.1 |
GRIÑó[ | 2003 | 西班牙 | 68 | 41(60.3) | ②阳性或③④⑥中至少有2项阳性 | 是 | - | 59(86.8) | 93.1 | 87.5 |
WINIARSKI[ | 2003 | 波兰 | 81 | - | ⑥阳性 | 否 | <24 h | 64(79.0) | 98.4 | 100.0 |
LIAO[ | 2003 | 中国 | 57 | 0 | ②③④中至少有2项阳性 | 否 | <24 h | 46(80.7) | 100.0 | 81.8 |
LO[ | 2005 | 中国 | 55 | 26(47.3) | ①阳性或②③④⑥中至少有3项阳性 | 否 | <24 h | 35(63.6) | 94.3 | 85.0 |
张厚德[ | 1997 | 中国 | 51 | - | ②和④均阳性 | - | <96 h | 42(82.4) | 73.8 | 100.0 |
林勇[ | 2004 | 中国 | 40 | - | ③和⑥均阳性 | 否 | - | 24(60.0) | 37.5 | 87.5 |
李舜[ | 2005 | 中国 | 31 | - | ②阳性 | 否 | - | 31(100.0) | 61.3 | - |
王醒[ | 2019 | 中国 | 116 | - | ②阳性 | 否 | 第5天 | 56(48.3) | 51.8 | 86.7 |
第一作者 | 发表时间(年) | 地区 | 样本量(例) | NSAIDs使用率〔n(%)〕 | H.pylori感染判定标准 | 是否纳入应用PPI或抗生素患者 | 平均取样时间 | 试剂盒 | H.pylori感染率〔n(%)〕 | 灵敏度(%) | 特异度(%) |
---|---|---|---|---|---|---|---|---|---|---|---|
LóPEZ PEÑAS[ | 2001 | 西班牙 | 32 | 18(56.3) | ②③④⑥中至少有2项阳性 | 否 | <24 h | 多克隆酶免疫试验 | 23(71.9) | 95.7 | 33.3 |
GRIÑó[ | 2003 | 西班牙 | 68 | 41(60.3) | ②阳性或③④⑥中至少有2项阳性 | 是 | <48 h | 多克隆酶免疫试验 | 59(86.8) | 96.6 | 33.3 |
PEITZ[ | 2003 | 德国 | 114 | 55(48.2) | ①阳性或②和③均阳性 | 是 | <24h | 多克隆酶免疫试验 | 56(49.1) | 83.9 | 89.7 |
PEITZ[ | 2003 | 德国 | 109 | - | ①阳性或②和③均阳性 | 是 | 第2天 | 多克隆酶免疫试验 | 53(48.6) | 79.2 | 87.5 |
VAN LEERDAM[ | 2003 | 荷兰 | 36 | 20(55.6) | ①阳性或②和③均阳性 | 否 | - | 多克隆酶免疫试验 | 15(41.7) | 100.0 | 52.4 |
LIN[ | 2004 | 中国 | 93 | - | ①阳性或②和③均阳性 | 否 | <72 h | 多克隆酶免疫试验 | 47(50.5) | 81.6 | 68.2 |
GISBERT[ | 2004 | 西班牙 | 34 | 22(64.7) | ②③④中至少有2项阳性 | 否 | 第2.8天 | 单克隆酶免疫试验 | 34(100.0) | 94.1 | - |
GISBERT[ | 2004 | 西班牙 | 34 | 22(64.7) | ②③④中至少有2项阳性 | 否 | 第2.8天 | 多克隆酶免疫试验 | 34(100.0) | 73.5 | - |
GISBERT[ | 2004 | 西班牙 | 34 | 22(64.7) | ②③④中至少有2项阳性 | 否 | 第2.8天 | HpSA免疫快检卡 | 34(100.0) | 58.8 | - |
于涛[ | 2006 | 中国 | 15 | - | ②③⑤中至少有2项阳性 | 否 | <24 h | HpSA免疫快检卡 | 10(66.7) | 100.0 | 80.0 |
王醒[ | 2019 | 中国 | 116 | - | ②阳性 | 否 | 第5天 | 单克隆免疫层析试验 | 56(48.3) | 91.1 | 83.3 |
Table 2 Basic characteristics of the SAT aimed to detect H.pylori infection in patients with peptic ulcer bleeding
第一作者 | 发表时间(年) | 地区 | 样本量(例) | NSAIDs使用率〔n(%)〕 | H.pylori感染判定标准 | 是否纳入应用PPI或抗生素患者 | 平均取样时间 | 试剂盒 | H.pylori感染率〔n(%)〕 | 灵敏度(%) | 特异度(%) |
---|---|---|---|---|---|---|---|---|---|---|---|
LóPEZ PEÑAS[ | 2001 | 西班牙 | 32 | 18(56.3) | ②③④⑥中至少有2项阳性 | 否 | <24 h | 多克隆酶免疫试验 | 23(71.9) | 95.7 | 33.3 |
GRIÑó[ | 2003 | 西班牙 | 68 | 41(60.3) | ②阳性或③④⑥中至少有2项阳性 | 是 | <48 h | 多克隆酶免疫试验 | 59(86.8) | 96.6 | 33.3 |
PEITZ[ | 2003 | 德国 | 114 | 55(48.2) | ①阳性或②和③均阳性 | 是 | <24h | 多克隆酶免疫试验 | 56(49.1) | 83.9 | 89.7 |
PEITZ[ | 2003 | 德国 | 109 | - | ①阳性或②和③均阳性 | 是 | 第2天 | 多克隆酶免疫试验 | 53(48.6) | 79.2 | 87.5 |
VAN LEERDAM[ | 2003 | 荷兰 | 36 | 20(55.6) | ①阳性或②和③均阳性 | 否 | - | 多克隆酶免疫试验 | 15(41.7) | 100.0 | 52.4 |
LIN[ | 2004 | 中国 | 93 | - | ①阳性或②和③均阳性 | 否 | <72 h | 多克隆酶免疫试验 | 47(50.5) | 81.6 | 68.2 |
GISBERT[ | 2004 | 西班牙 | 34 | 22(64.7) | ②③④中至少有2项阳性 | 否 | 第2.8天 | 单克隆酶免疫试验 | 34(100.0) | 94.1 | - |
GISBERT[ | 2004 | 西班牙 | 34 | 22(64.7) | ②③④中至少有2项阳性 | 否 | 第2.8天 | 多克隆酶免疫试验 | 34(100.0) | 73.5 | - |
GISBERT[ | 2004 | 西班牙 | 34 | 22(64.7) | ②③④中至少有2项阳性 | 否 | 第2.8天 | HpSA免疫快检卡 | 34(100.0) | 58.8 | - |
于涛[ | 2006 | 中国 | 15 | - | ②③⑤中至少有2项阳性 | 否 | <24 h | HpSA免疫快检卡 | 10(66.7) | 100.0 | 80.0 |
王醒[ | 2019 | 中国 | 116 | - | ②阳性 | 否 | 第5天 | 单克隆免疫层析试验 | 56(48.3) | 91.1 | 83.3 |
Figure 9 Comprehensive receiver operating characteristic curve of the UBT and SAT aimed to detect H.pylori infection in patients with peptic ulcer bleeding
检查方式 | 亚组 | 研究数量(项) | 合并灵敏度 | 合并特异度 | 合并诊断比值比 | 合并阳性似然比 | 合并阴性似然比 | SROC曲线下面积 |
---|---|---|---|---|---|---|---|---|
UBT | 取样时间<24 h | 8[ | 0.94(0.91,0.96) | 0.92(0.85,0.96) | 119.27(49.06,289.94) | 7.78(4.04,14.97) | 0.09(0.05,0.17) | 0.97(0.96,0.98) |
取样时间>3 d | 3[ | 0.69(0.60,0.76) | 0.88(0.78,0.94) | 11.84(2.01,69.85) | 4.37(1.93,9.89) | 0.41(0.21,0.80) | 0.81(0.78,0.83) | |
复合标准 | 10[ | 0.89(0.86,0.92) | 0.87(0.77,0.93) | 46.65(14.98,145.29) | 5.30(3.10,9.06) | 0.15(0.06,0.37) | 0.92(0.89,0.94) | |
单一标准 | 4[ | 0.76(0.70,0.82) | 0.92(0.86,0.96) | 87.63(4.42,173.31) | 11.53(2.09,63.66) | 0.14(0.02,0.81) | 0.94(0.92,0.96) | |
SAT | 取样时间<24 h | 3[ | 0.89(0.80,0.95) | 0.82(0.71,0.90) | 37.24(14.19,97.76) | 3.47(0.74,16.14) | 0.17(0.09,0.30) | 0.93(0.90,0.95) |
取样时间2~3 d | 6[ | 0.82(0.77,0.87) | 0.75(0.66,0.82) | 15.26(7.76,30.01) | 2.77(1.23,6.24) | 0.24(0.16,0.35) | 0.87(0.80,0.95) |
Table 3 Subgroup analysis results of the UBT and SAT aimed to detect H.pylori infection in patients with peptic ulcer bleeding
检查方式 | 亚组 | 研究数量(项) | 合并灵敏度 | 合并特异度 | 合并诊断比值比 | 合并阳性似然比 | 合并阴性似然比 | SROC曲线下面积 |
---|---|---|---|---|---|---|---|---|
UBT | 取样时间<24 h | 8[ | 0.94(0.91,0.96) | 0.92(0.85,0.96) | 119.27(49.06,289.94) | 7.78(4.04,14.97) | 0.09(0.05,0.17) | 0.97(0.96,0.98) |
取样时间>3 d | 3[ | 0.69(0.60,0.76) | 0.88(0.78,0.94) | 11.84(2.01,69.85) | 4.37(1.93,9.89) | 0.41(0.21,0.80) | 0.81(0.78,0.83) | |
复合标准 | 10[ | 0.89(0.86,0.92) | 0.87(0.77,0.93) | 46.65(14.98,145.29) | 5.30(3.10,9.06) | 0.15(0.06,0.37) | 0.92(0.89,0.94) | |
单一标准 | 4[ | 0.76(0.70,0.82) | 0.92(0.86,0.96) | 87.63(4.42,173.31) | 11.53(2.09,63.66) | 0.14(0.02,0.81) | 0.94(0.92,0.96) | |
SAT | 取样时间<24 h | 3[ | 0.89(0.80,0.95) | 0.82(0.71,0.90) | 37.24(14.19,97.76) | 3.47(0.74,16.14) | 0.17(0.09,0.30) | 0.93(0.90,0.95) |
取样时间2~3 d | 6[ | 0.82(0.77,0.87) | 0.75(0.66,0.82) | 15.26(7.76,30.01) | 2.77(1.23,6.24) | 0.24(0.16,0.35) | 0.87(0.80,0.95) |
[1] | LAINE L, BARKUN A N, SALTZMAN J R,et al. ACG clinical guideline:upper gastrointestinal and ulcer bleeding[J]. Am J Gastroenterol,2021,116(5):899-917. DOI:10.14309/ajg.0000000000001245. |
[2] | 王锦萍,崔毅,王锦辉,等. 上消化道出血15年临床流行病学变化趋势[J]. 中华胃肠外科杂志,2017,20(4):425-431. DOI:10.3760/cma.j.issn.1671-0274.2017.04.012. |
[3] | 中华消化杂志编辑委员会,中华消化外科杂志编辑委员会. 急性非静脉曲张性上消化道出血多学科防治共识[J]. 中华消化杂志,2019,39(12):793-799. DOI:10.3760/cma.j.issn.0254-1432.2019.12.001. |
[4] | 邬兰,张永,曾宪涛. QUADAS-2在诊断准确性研究的质量评价工具中的应用[J]. 湖北医药学院学报,2013,32(3):201-208. |
[5] | 曾宪涛,何明武. 诊断准确性试验Meta分析软件一本通[M]. 北京:军事医学科学出版社,2014. |
[6] | 周支瑞,胡志德. 疯狂统计学[M]. 长沙:中南大学出版社,2018. |
[7] | 吴景玲,葛龙,张俊华,等. 多个诊断性试验准确性的比较:网状Meta分析方法介绍[J]. 中国循证医学杂志,2017,17(8):987-992. DOI:10.7507/1672-2531.201706041. |
[8] | 高亚,孙凤,武珊珊,等. 网络Meta分析研究进展系列(五):诊断试验准确性网络Meta分析[J]. 中国循证心血管医学杂志,2020,12(10):1161-1165. DOI:10.3969/j.issn.1674-4055.2020.10.03. |
[9] | TU T C, LEE C L, WU C H,et al. Comparison of invasive and noninvasive tests for detecting Helicobacter pylori infection in bleeding peptic ulcers[J]. Gastrointest Endosc,1999,49(3 Pt 1):302-306. DOI:10.1016/s0016-5107(99)70005-2. |
[10] | LóPEZ PEÑAS D, NARANJO RODRíGUEZ A, MUÑOZ MOLINERO J,et al. Efficacy of fecal detection of Helicobacter pylori with the HpSA technique in patients with upper digestive hemorrhage[J]. Gastroenterol Hepatol,2001,24(1):5-8. |
[11] | GRIÑó P, PASCUAL S, SUCH J,et al. Comparison of diagnostic methods for Helicobacter pylori infection in patients with upper gastrointestinal bleeding[J]. Scand J Gastroenterol,2001,36(12):1254-1258. DOI:10.1080/003655201317097083. |
[12] | CHUNG I K, HONG S J, KIM E J,et al. What is the best method to diagnose Helicobacter infection in bleeding peptic ulcers?:a prospective trial[J]. Korean J Intern Med,2001,16(3):147-152. DOI:10.3904/kjim.2001.16.3.147. |
[13] | WILDNER-CHRISTENSEN M, TOUBORG LASSEN A, LINDEBJERG J,et al. Diagnosis of Helicobacter pylori in bleeding peptic ulcer patients,evaluation of urea-based tests[J]. Digestion,2002,66(1):9-13. DOI:10.1159/000064421. |
[14] | GRIÑó P, PASCUAL S, SUCH J,et al. Comparison of stool immunoassay with standard methods for detection of Helicobacter pylori infection in patients with upper-gastrointestinal bleeding of peptic origin[J]. Eur J Gastroenterol Hepatol,2003,15(5):525-529. DOI:10.1097/01.meg.0000059114.41030.a9. |
[15] | WINIARSKI M, BIELANSKI W, PLONKA M,et al. The usefulness of capsulated 13C-urea breath test in diagnosis of Helicobacter pylori infection in patients with upper gastrointestinal bleeding[J]. J Clin Gastroenterol,2003,37(1):34-38. DOI:10.1097/00004836-200307000-00010. |
[16] | LIAO C C, LEE C L, LAI Y C,et al. Accuracy of three diagnostic tests used alone and in combination for detecting Helicobacter pylori infection in patients with bleeding gastric ulcers[J]. Chin Med J (Engl),2003,116(12):1821-1826. |
[17] | LO C C, LAI K H, PENG N J,et al. Polymerase chain reaction:a sensitive method for detecting Helicobacter pylori infection in bleeding peptic ulcers[J]. World J Gastroenterol,2005,11(25):3909-3914. DOI:10.3748/wjg.v11.i25.3909. |
[18] | 张厚德,杜冀晖,苏卓娃,等. 上消化道出血对14C-尿素呼气试验准确性影响[J]. 胃肠病学和肝病学杂志,1997,6(2):66-67. |
[19] | 林勇,李荣洲,郑超秀,等. 14C-尿素呼气试验在消化性溃疡并出血病人假阴性原因分析[J]. 浙江临床医学,2004,6(7):577. DOI:10.3969/j.issn.1008-7664.2004.07.023. |
[20] | 李舜,张家云,邓咏梅. 14C-尿素呼气试验在不同胃黏膜病变中的诊断价值及影响因素分析[J]. 实用医学杂志,2005,21(5):477-478. DOI:10.3969/j.issn.1006-5725.2005.05.015. |
[21] | 王醒,高广周,石峥,等. 粪便幽门螺杆菌检测在上消化道溃疡出血患者中的价值[J]. 世界最新医学信息文摘,2019,19(25):165-166. DOI:10.19613/j.cnki.1671-3141.2019.25.123. |
[22] | PEITZ U, LEODOLTER A, KAHL S,et al. Antigen stool test for assessment of Helicobacter pylori infection in patients with upper gastrointestinal bleeding[J]. Aliment Pharmacol Ther,2003,17(8):1075-1084. DOI:10.1046/j.1365-2036.2003.01548.x. |
[23] | VAN LEERDAM M E, VAN DER ENDE A, TEN KATE F J,et al. Lack of accuracy of the noninvasive Helicobacter pylori stool antigen test in patients with gastroduodenal ulcer bleeding[J]. Am J Gastroenterol,2003,98(4):798-801. DOI:10.1111/j.1572-0241.2003.07387.x. |
[24] | LIN H J, LO W C, PERNG C L,et al. Helicobacter pylori stool antigen test in patients with bleeding peptic ulcers[J]. Helicobacter,2004,9(6):663-668. DOI:10.1111/j.1083-4389.2004.00276.x. |
[25] | GISBERT J P, TRAPERO M, CALVET X,et al. Evaluation of three different tests for the detection of stool antigens to diagnose Helicobacter pylori infection in patients with upper gastrointestinal bleeding[J]. Aliment Pharmacol Ther,2004,19(8):923-929. DOI:10.1111/j.1365-2036.2004.01932.x. |
[26] | 于涛. 幽门螺杆菌粪便抗原检测卡的应用及质子泵抑制剂对其结果的影响[D]. 广州:中山大学,2006. |
[27] | 田金徽,陈杰峰. 诊断试验系统评价/Meta分析指导手册[M]. 北京:中国医药科技出版社,2015. |
[28] | MALFERTHEINER P, MEGRAUD F, O'MORAIN C A,et al. Management of Helicobacter pylori infection-the maastricht V/Florence consensus report[J]. Gut,2017,66(1):6-30. DOI:10.1136/gutjnl-2016-312288. |
[29] | 中华医学会,中华医学会杂志社,中华医学会全科医学分会,等. 幽门螺杆菌感染基层诊疗指南(2019年)[J]. 中华全科医师杂志,2020,19(5):397-402. DOI:10.3760/cma.j.cn114798-20200223-00158. |
[30] | 《中华内科杂志》编辑委员会,《中华医学杂志》编辑委员会,《中华消化杂志》编辑委员会,等. 急性非静脉曲张性上消化道出血诊治指南(2018年,杭州)[J]. 中华内科杂志,2019,58(3):173-180. DOI:10.3760/cma.j.issn.0578-1426.2019.03.005. |
[1] | WANG Zhe, DONG Zhihao, ZHENG Hao, KONG Wencheng, ZHANG Yukuan, ZHANG Qiuyue, HAN Jing. Construction of Optimized Treatment Plan of Acupuncture for Migraine Based on Entropy Weight-TOPSIS Method [J]. Chinese General Practice, 2023, 26(34): 4336-4342. |
[2] | WANG Yue, CHEN Qing, LIU Lurong. Detection Rate of Depression and Its Influencing Factors in Chinese Elderly: a Meta-analysis [J]. Chinese General Practice, 2023, 26(34): 4329-4335. |
[3] | JIAN Qiufeng, XU Ronghua, YAO Qian, ZHOU Yuanyuan. A Meta-analysis of the Prevalence and Influencing Factors of Post-stroke Cognitive Impairment in Chinese Elderly Patients [J]. Chinese General Practice, 2023, 26(32): 4070-4079. |
[4] | JIA Yu, ZHOU Zitong, CAO Xuehua, HU Wanqin, XIANG Feng, XIONG Langyu, WANG Xiaoxia. Incidence of Perimenopausal Syndrome in Chinese Women Aged 40 to 65 Years: a Meta-analysis [J]. Chinese General Practice, 2023, 26(32): 4080-4088. |
[5] | LI Jixin, QIU Linjie, REN Yan, WANG Wenru, LI Meijie, ZHANG Jin. The Correlation of Dietary Inflammatory Index with Overweight, Obesity and Abdominal Obesity: a Meta-analysis [J]. Chinese General Practice, 2023, 26(32): 4089-4097. |
[6] | HE Jingyi, WANG Fang, SHUI Xiaoling, LI Ling, LIANG Qian. Efficacy of Non-pharmacological Interventions to Improve Perimenopausal Insomnia Symptoms: a Network Meta-analysis [J]. Chinese General Practice, 2023, 26(31): 3963-3974. |
[7] | ZHU Lin, GUO Yankui, GAO Chen, CHEN Xuezhi, WANG Fashuai. Efficacy of Western Medicine, Chinese Patent Medicine and Their Combination on Post-stroke Insomnia: a Network Meta-analysis [J]. Chinese General Practice, 2023, 26(30): 3823-3832. |
[8] | ZHANG Dongli, SHEN Chong, ZHANG Weichuan, CHEN Haibin, ZHAO Jianjun. Efficacy and Safety of Programmed Death-1/Programmed Death-1 Ligand Inhibitors in the Treatment of Renal Cell Cancer: a Meta-analysis [J]. Chinese General Practice, 2023, 26(30): 3815-3822. |
[9] | HE Li, ZHANG Yifan, SHEN Xuechun, SUN Yan, ZHAO Yang. Prevalence Trends of Multimorbidity among Residents in Mainland China: a Meta-analysis [J]. Chinese General Practice, 2023, 26(29): 3599-3607. |
[10] | LIN Yang, WANG Fang, WANG Han, WU Rong, WANG Yao, XU Ziyao, WANG Xu, WANG Yanding. Prevalence of Frailty in Elderly Patients with Comorbidity: a Meta-analysis [J]. Chinese General Practice, 2023, 26(25): 3185-3193. |
[11] | GUO Yinning, MIAO Xueyi, JIANG Xiaoman, XU Ting, XU Qin. Effects of Protein Supplementation on Muscle Mass, Strength, and Physical Function in Frail/Pre-frail Older Adults: a Meta-analysis [J]. Chinese General Practice, 2023, 26(23): 2854-2863. |
[12] | WANG Xueyan, TIAN Jinhui, ZHANG Li, ZHAI Jinguo. Effects of Different Intervention Measures for Breech Presentation/Transverse Lie Position on Maternal and Neonatal Outcomes: a Network Meta-analysis [J]. Chinese General Practice, 2023, 26(21): 2647-2658. |
[13] | WANG Shumin, LI Xuejun, ZHANG Yixing, JIANG Zhiyan, XIAO Zhen. Correlation between Mycoplasma Pneumoniae Infection and Coronary Artery Lesions in Mucocutaneous Lymph Node Syndrome: a Meta-analysis [J]. Chinese General Practice, 2023, 26(20): 2532-2539. |
[14] | XUE Shan, LI Laiyou, LIANG Junli, JIN Yinghui, WEI Shuyan. The Efficacy and Safety of Home Enteral Nutrition in Patients with Esophageal Cancer: a Meta-analysis [J]. Chinese General Practice, 2023, 26(20): 2540-2547. |
[15] | LIU Lu, JIANG Yunlan, PENG Hanmei, LU Yutong, LIU Mingting, LIAO Shiqin. Dysphagia Incidence after Cardiac Surgery: a Meta-analysis [J]. Chinese General Practice, 2023, 26(18): 2293-2300. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||