Colorectal Cancer Screening Program in China：Recent Advances and Screening Dilemma

doi:10.12114/j.issn.1007-9572.2021.00.480

Abstract

Abstract: In recent years，the incidence and mortality of colorectal cancer （CRC） in China are increasing rapidly. But CRC screening is quite feasible，because its development from normal intestinal mucosa to abnormal growth and to malignancy can last for decades，which makes early screening and removal of precancerous colorectal lesions before cancerization become possible. Increasing countries aim to reduce high incidence and mortality of CRC and enhance its current low early diagnosis rate via implementing CRC screening programs. We reviewed recent advances in the common methods and means as well as relevant studies regarding CRC screening，providing a reference for clinical practice.

Key words: Colorectal neoplasms, Early detection of cancer, Mass screening

摘要： 近年来，我国结直肠癌的发病率及死亡率呈上升趋势且增长迅速。大多数结直肠癌从正常肠黏膜到异常增生，再到最终恶性变的发展过程长达数十年，该时机使结直肠癌平均风险个体发生癌变之前就检测和移除早期癌前病变成为可能，这一生物学特性使其成为理想的在人群中进行筛查的癌症之一。现阶段，越来越多的国家拟通过在人群中进行结直肠癌筛查来改变结直肠癌高发病率、高死亡率和早期低诊断率的现状。本文阐述了常用结直肠癌筛查方法及手段，总结了结直肠癌筛查的研究现状，以期为临床实践提供参考。

关键词: 结直肠肿瘤, 癌症早期检测, 普查

HAN Xi,LIU Jun,MA Qi, et al. Colorectal Cancer Screening Program in China：Recent Advances and Screening Dilemma　[J]. Chinese General Practice, 2021, 24(33): 4172-4176. DOI: 10.12114/j.issn.1007-9572.2021.00.480.
韩西,刘君,马麒等. 我国结直肠癌筛查方案的研究进展及筛查困境分析[J]. 中国全科医学, 2021, 24(33): 4172-4176. DOI: 10.12114/j.issn.1007-9572.2021.00.480.

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