Recent Advances in Diabetic Cystopathy

doi:10.12114/j.issn.1007-9572.2019.00.366

Abstract

Abstract: We systematically reviewed recent advances in diabetic cystopathy at home and abroad.On the basis of summarizing epidemiological characteristics and research history of diabetic cystopathy，we analyzed the pathogenesis of this disease from a novel perspective of detrusor cell injury，nerve pathway disorder and urinary tract dysfunction，and found that the treatment of detrusor injury has become a hot research topic.Many researchers are trying new methods other than traditional treatment（urine training，pharmacological therapy，integrated Chinese and western treatment，etc.）.In addition，various physiotherapies and bladder repair using tissue engineering technologies are emerging.These new treatment ideas are current research hotspots and indicate the focus of future clinical applications.

Key words: Diabetic cystopathy, Diabetes complications, Epidemiology, Signs and symptoms, Therapy, Review

摘要： 本文系统回顾了当前国内外在糖尿病膀胱领域的研究进展，在总结流行病学特点，疾病研究历史的基础上，以逼尿肌细胞损伤、神经传导通路障碍、尿道功能异常全新的结构框架梳理糖尿病膀胱的发病机制；特别是发现针对逼尿肌细胞损伤的治疗已经成为目前的研究热点，许多研究者在尝试传统治疗（排尿训练、药物治疗、中西医结合等）以外的新方法，各种物理疗法和基于组工学的膀胱修复技术层出不穷，这些新的治疗思路是目前的研究热点亦预示着将来临床应用的重点。

关键词: 糖尿病膀胱, 糖尿病并发症, 流行病学, 体征和症状, 治疗, 综述

GUO Wenmin,SUN Libin,WANG Dongwen. Recent Advances in Diabetic Cystopathy　[J]. Chinese General Practice, 2020, 23(17): 2095-2101. DOI: 10.12114/j.issn.1007-9572.2019.00.366.
郭文敏,孙李斌,王东文. 糖尿病膀胱研究进展[J]. 中国全科医学, 2020, 23(17): 2095-2101. DOI: 10.12114/j.issn.1007-9572.2019.00.366.

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