Advances in Research on Association between Sleep Duration and Stroke and Its Risk Factors

doi:10.12114/j.issn.1007-9572.2019.00.631

Abstract

Abstract: Stroke is a leading cause of death and disability worldwide.While numerous traditional risk factors（such as hypertension，diabetes，dyslipidemia，atrial fibrillation and obesity） have been identified for stroke，inappropriate sleep duration has only been considered as a risk factor in recent years.Various epidemiologic studies have associated stroke with sleep duration.The purpose of this review is to provide an update on the relationship between sleep duration and risk factors of stroke in order to increase doctors' awareness of sleep duration and to provide a reference for stroke prevention in the people who have high-risk factors of stroke.

Key words: Stroke, Sleep, Risk factors, Review

摘要： 脑卒中是世界范围内主要的致死和致残原因。虽然多种传统的脑卒中危险因素（如高血压、糖尿病、血脂异常、心房颤动、肥胖等）已经被确定，然而不适当的睡眠时长却是近年来才被认识的脑卒中危险因素。越来越多的流行病学调查显示，睡眠时长和脑卒中存在关联。本文旨在对睡眠时长与脑卒中及其危险因素之间关系的研究进行综述，以提高医生对睡眠时长的认识，为脑卒中高危人群的脑卒中预防提供参考。

关键词: 卒中, 睡眠, 危险因素, 综述

WANG Weihua,CUI Shibei,JI Xiaowen, et al. Advances in Research on Association between Sleep Duration and Stroke and Its Risk Factors　[J]. Chinese General Practice, 2019, 22(31): 3897-3901. DOI: 10.12114/j.issn.1007-9572.2019.00.631.
王卫华,崔时贝,纪晓雯等. 睡眠时长与脑卒中及其危险因素间关系的研究进展[J]. 中国全科医学, 2019, 22(31): 3897-3901. DOI: 10.12114/j.issn.1007-9572.2019.00.631.

References

［1］赵冬．我国人群脑卒中发病率、死亡率的流行病学研究［J］．中华流行病学杂志，2002，22（z1）：49-53．DOI：10.3760/j.issn:0254-6450.2002.z1.017.http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zhlxbx2002z1017.
［2］马冠生，崔朝辉，胡小琪，等．中国居民的睡眠时间分析［J］．中国慢性病预防与控制，2006，14（2）：68-71．DOI：10.3969/j.issn.1004-6194.2006.02.002.
MA G S，CUI C H，HU X Q，et al．Analysis on sleeping time among Chinese population［J］．Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases，2006，14（2）：68-71．DOI：10.3969/j.issn.1004-6194.2006.02.002．
［3］HE Q，SUN H，WU X，et al．Sleep duration and risk of stroke：a dose–response meta-analysis of prospective cohort studies［J］．Sleep Med，2017，32（5）：66-74．DOI：10.1016/j.sleep.2016.12.012．
［4］GE B，GUO X.Short and long sleep durations are both associated with increased risk of stroke：a meta-analysis of observational studies［J］．Int J Stroke，2015，10（2）：177-184．DOI：10.1111/ijs.12398．
［5］MENG L，ZHENG Y，HUI R.The relationship of sleep duration and insomnia to risk of hypertension incidence：a meta-analysis of prospective cohort studies［J］．Hypertension Research，2013，36（11）：985-995．DOI：10.1038/hr.2013.70．
［6］田沈，赵洋，甘秀红，等．辽宁省锦州市农村居民睡眠时间与高血压的相关性［J］．中国慢性病预防与控制，2015，23（7）：495-497，501．DOI：10.16386/j.cjpccd.issn.1004-6194.2015.07.005．
TIAN S，ZHAO Y，GAN X H，et al．Investigation of the relationship between sleep duration and hypertension in rural residents in Liaoning Province［J］．Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases，2015，23（7）：495-497，501．DOI：10.16386/j.cjpccd.issn.1004-6194.2015.07.005．
［7］GUO J，FEI Y，LI J，et al．Gender-and age-specific associations between sleep duration and prevalent hypertension in middle-aged and elderly Chinese：a cross-sectional study from CHARLS 2011—2012［J］．BMJ Open，2016，6（9）：e011770．DOI：10.1136/bmjopen-2016-011770.
［8］KNUTSON K L，CAUTER E V，RATHOUZ P J，et al．Association between sleep and blood pressure in midlife：the CARDIA sleep study［J］．Arch Intern Med，2016，169（11）：1055-1061．DOI：10.1001/archinternmed.2009.119.
［9］GOTTLIEB D J，REDLINE S，NIETO F J，et al．Association of usual sleep duration with hypertension：the sleep heart health study［J］．Sleep，2006，29（8）：1009-1014．DOI：10.1093/sleep/29.8.1009.
［10］MAGEE C A，KRITHARIDES L，ATTIA J，et al．Short and long sleep duration are associated with prevalent cardiovascular disease in Australian adults［J］．J Sleep Res，2012，21（4）：441-447．DOI：10.1111/j.1365-2869.2011.00993.x.
［11］YAN W，HAO M，YAN-RUI J，et al．Relationship between duration of sleep and hypertension in adults：a meta-analysis［J］．J Clin Sleep Med，2015，11（9）：1047-1056．DOI：10.5664/jcsm.5024.
［12］SUN X，YAO S，HU S，et al．Short sleep duration is associated with increased risk of pre-hypertension and hypertension in Chinese early middle-aged females［J］．Sleep Breath，2016，20（4）：1355-1362．DOI：10.1007/s11325-016-1392-2.
［13］LUSARDI P，ZOPPI A，PRETI P，et al．Effects of insufficient sleep on blood pressure in hypertensive patients：a 24-h study［J］．Hypertention，1999，12（1）：63-68．DOI：10.1016/S0895-7061（98）00200-3.
［14］LUSARDI P，MUGELLINI A，PRETI P，et al．Effects of a restricted sleep regimen on ambulatory blood pressure monitoring in normotensive subjects［J］．AM J Hypertens，1996，9（5）：503-505．DOI：10.1016/0895-7061（95）00389-4.
［15］查龙肖，周权，李风英，等．睡眠时间与2型糖尿病发病风险关系前瞻性研究的meta分析［J］．中国全科医学，2016，19（26）：3196-3203．DOI：10.3969/j.jssn.1007-9572.2016.26.014.
ZHA L X，ZHOU Q，LI F Y，et al．Relationship between length of sleep and incidence risk of type 2 diabetes：a meta-analysis of prospective studies［J］．Chinese General Practice，2016，19（26）：3196-3203．DOI：10.3969/j.issn.1007-9572.2016.26.014.
［16］MASKARINEC G，JACOBS S，AMSHOFF Y，et al．Sleep duration and incidence of type 2 diabetes：the multiethnic cohort［J］．Sleep Health，2018，4（1）：27-32．DOI：10.1016/j.sleh.2017.08.008.
［17］KUHN E，BRODAN V，BRODANOVá M，et al．Metabolic reflection of sleep deprivation［J］Act Nerv Super（Praha），1969，11（3）：165-174.
［18］SHAN Z，MA H，XIE M，et al．Sleep duration and risk of type 2 diabetes：a meta-analysis of prospective studies［J］．Diabetes Care，2015，38（3）：529-537．DOI：10.2337/dc14-2073.
［19］HOLLIDAY E G，MAGEE C A，KRITHARIDES L，et al．Short sleep duration is associated with risk of future diabetes but not cardiovascular disease：a prospective study and meta-analysis［J］．PLoS One，2013，8（11）：e82305．DOI：10.1371/journal.pone.0082305.
［20］OHKUMA T，FUJII H，IWASE M，et al．Impact of sleep duration on obesity and the glycemic level in patients with type 2 diabetes：the fukuoka diabetes registry［J］．Diabetes Care，2013，36（3）：611-617．DOI：10.2337/dc12-0904.
［21］FLINT J，KOTHARE S V，ZIHLIF M，et al．Association between inadequate sleep and insulin resistance in obese children［J］．J Pediatr，2007，150（4）：364-369．DOI：10.1016/j.jpeds.2006.08.063.
［22］KIM T W，JEONG J H，HONG S C.The impact of sleep and circadian disturbance on hormones and metabolism［J］．Int J Endocrinol，2015，11（3）：1-9．DOI：10.1155/2015/591729.
［23］BROUSSARD J L，WROBLEWSKI K，KILKUS J M，et al．Two nights of recovery sleep reverses the effects of short-term sleep restriction on diabetes risk［J］．Diabetes Care，2016，39（3）：e40-41．DOI：10.2337/dc15-2214.
［24］LIND P M，CHANG K T，LIN Y A，et al．Association between self-reported sleep duration and serum lipid profile in a middle-aged and elderly population in Taiwan：a community-based，cross-sectional study［J］．BMJ Open，2017，7（10）：e015964．DOI：10.1136/bmjopen-2017-015964.
［25］PETROV M E，KIM Y，LAUDERDALE D，et al．Longitudinal associations between objective sleep and lipids：the CARDIA study［J］．Sleep，2013，36（11）：1587-1595．DOI：10.5665/sleep.3104.
［26］KANEITA Y，UCHIYAMA M，YOSHIIKE N，et al．Associations of usual sleep duration with serum lipid and lipoprotein levels［J］．Sleep，2008，31（5）：645-652．DOI：10.1055/s-2007-1023230.
［27］ZHAN Y，CHEN R，YU J.Sleep duration and abnormal serum lipids：the China health and nutrition survey［J］．Sleep Med，2014，15（7）：833-839．DOI：10.1016/j.sleep.2014.02.006.
［28］SHIN H Y，KANG G，KIM S W，et al．Associations between sleep duration and abnormal serum lipid levels：data from the Korean national health and nutrition examination survey（KNHANES）［J］．Sleep Med，2016，24：119-123．DOI：10.1016/j.sleep.2016.05.012.
［29］GREER S M，GOLDSTEIN A N，WALKER M P.The impact of sleep deprivation on food desire in the human brain［J］．Nat Commun，2013，4（4）：2259．DOI：10.1038/ncomms3259.
［30］FANG Z，SPAETH A M，MA N，et al．Altered salience network connectivity predicts macronutrient intake after sleep deprivation［J］．Sci Rep，2015，5（1）：8210-8215．DOI：10.1038/srep08215.
［31］WOLF P A，DAWBER T R，JR T H，et al．Epidemiologic assessment of chronic atrial fibrillation and risk of stroke：the Framingham study［J］．Neurology，1978，28（10）：973-977．DOI：10.1212/WNL.28.10.973.
［32］SONG Q，LIU X，HU W，et al．Long sleep duration is an independent risk factor for incident atrial fibrillation in a Chinese population：a prospective cohort study［J］．Sci Rep，2017，7（1）：3679．DOI：10.1038/s41598-017-04034-8.
［33］KOKUBO Y，KOBAYASHI T，WATANBE M，et al．A prospective study of sleep duration and the risk of incident atrial fibrillation in an urban population：the Suita study ［J］．J AM Coll Cardiol，2014，63（12）：a1434．DOI：10.1016/S0735-1097（14）61434-0.
［34］IBRAHIM S M D，VEDAT D M D，BURCU O M D，et al．Acute sleep deprivation is associated with increased electrocardiographic p‐wave dispersion in healthy young men and women［J］．PACE，2010，31（4）：438-442．DOI：10.1111/j.1540-8159.2008.01013.x.
［35］?ZLEMESEN M D，MUSTAFA A M D，G?KSEL A M D，et al．Acute sleep deprivation is associated with increased atrial electromechanical delay in healthy young adults［J］．Pace，2011，34（12）：1645-1651．DOI：10.1111/j.1540-8159.2011.03186.x.
［36］HASLER G，BUYSSE D J，KLAGHOFER R，et al．The association between short sleep duration and obesity in young adults：a 13-year prospective study［J］．Sleep，2004，27（4）：661-666．DOI：10.1093/sleep/27.4.661.
［37］MAGEE C A，CAPUTI P，IVERSON D C.Is sleep duration associated with obesity in older Australian adults?［J］．J Aging Health，2010，22（8）：1235-1255．DOI：10.1177/0898264310372780.
［38］VAN S T，KOENDERS P G.Effects of emotional eating and short sleep duration on weight gain in female employees［J］．J Occup Environ Med，2014，56（6）：659-666．DOI：10.1097/JOM.0000000000000172.
［39］LYYTIK?INEN P，RAHKONEN O，LAHELMA E，et al．Association of sleep duration with weight and weight gain：a prospective follow-up study［J］．J Sleep Res，2011，20（2）：298-302．DOI：10.1111/j.1365-2869.2010.00903.x.
［40］MORSELLI L，LEPROULT R，BALBO M，et al．Role of sleep duration in the regulation of glucose metabolism and appetite［J］．Best Pract Res Cl En，2010，24（5）：687-702．DOI：10.1016/j.beem.2010.07.005.
［41］SCHMID S M，HALLSCHMID M，JAUCH CHARA K，et al．Short-term sleep loss decreases physical activity under free-living conditions but does not increase food intake under time-deprived laboratory conditions in healthy men［J］．AM J Clin Nutr，2009，90（6）：1476-1482．DOI：10.3945/ajcn.2009.27984.

[1]	QIN Fengyin, ZHANG Qishan, LAI Jinjia, HUANG Yimin, HAN Guoyin, SUN Xinglan, WANG Fen, TAN Yibing. Current Status and Influencing Factors of the Intention to Screen for High-risk Stroke among Community Residents in Guangdong [J]. Chinese General Practice, 2023, 26(34): 4283-4289.
[2]	LIANG Xuan, NA Feiyang, QIN Mengyao, YANG Hui, GUO Li, GUO Qi, REN Lei, CHEN De, LIU Donghai, ZHANG Rongfang. Clinical Characteristics and Influencing Factors of Bronchial Asthma Combined with Obstructive Sleep Apnea-hypopnea Syndrome in Children [J]. Chinese General Practice, 2023, 26(33): 4225-4230.
[3]	SU Kaiqi, LYU Zhuan, WU Mingli, LUO Meng, GAO Jing, NIE Chenchen, LIU Hao, FENG Xiaodong. Effect of Electroacupuncture on BDNF/TrkB/PI3K/Akt Pathway and Hippocampal Neuronal Protection in Rats with Learning and Memory Impairment after Ischemia Reperfusion [J]. Chinese General Practice, 2023, 26(33): 4187-4193.
[4]	YU Xinlian, DAI Xinyue, ZHAO Xicun, XU Ying. Chain Mediating Effects of Stressful Life Events and the Time Taken to Fall Asleep in the Relationship between Yin-deficiency Constitution and Depressed Mood in Junior High School Students [J]. Chinese General Practice, 2023, 26(33): 4159-4166.
[5]	YIN Miaomiao, CUI Liling, LI Yaqing, WANG Liqun, ZHANG Yue, WU Jialing. Effect of Dual Task on Walking Ability in Posterior Circulation Ischemic Stroke Patients with Vestibular Symptoms [J]. Chinese General Practice, 2023, 26(33): 4207-4212.
[6]	LIU Weina, GE Haiyan, MA Jing, CAO Qinying, BAI Xingyu, CUI Shifang, QIAO Yanxia. A Study on the Relationship of Vitamin A and E Levels in Umbilical Cord Blood with Respiratory Distress Syndrome in Preterm Infants [J]. Chinese General Practice, 2023, 26(33): 4152-4158.
[7]	LI Jixin, QIU Linjie, REN Yan, WANG Wenru, LI Meijie, ZHANG Jin. The Correlation of Dietary Inflammatory Index with Overweight, Obesity and Abdominal Obesity: a Meta-analysis [J]. Chinese General Practice, 2023, 26(32): 4089-4097.
[8]	MA Liyuan, WANG Zengwu, FAN Jing, HU Shengshou. Interpretation of Report on Cardiovascular Health and Diseases in China 2022 [J]. Chinese General Practice, 2023, 26(32): 3975-3994.
[9]	LI Yujing, JIN Yichao, CHEN Xing, JI Mengying, DAI Huihua. Risk Factors for Endometrial Lesions Detected by Hysteroscopy in Breast Cancer Patients Taking Tamoxifen [J]. Chinese General Practice, 2023, 26(32): 4026-4030.
[10]	JIAN Qiufeng, XU Ronghua, YAO Qian, ZHOU Yuanyuan. A Meta-analysis of the Prevalence and Influencing Factors of Post-stroke Cognitive Impairment in Chinese Elderly Patients [J]. Chinese General Practice, 2023, 26(32): 4070-4079.
[11]	YANG Yuxuan, ZHANG Han, DU Juan, WANG Lingling, XIE Yulei, YIN Kaiming, ZHANG Bo. Value of an Dynamic Eye-tracking Task in Assessing Unilateral Spatial Neglect after Stroke [J]. Chinese General Practice, 2023, 26(32): 4020-4025.
[12]	QU Hui, LI Huan, TANG Ruohan, DU Yuzheng, ZHAO Qi. Outcome Indicators Analysis of Randomized Controlled Trials of Acupuncture for Obstructive Sleep Apnea Hypopnea Syndrome in the Past Decade [J]. Chinese General Practice, 2023, 26(30): 3734-3739.
[13]	WEN Wen, ZHANG Kainan, CHEN Yulan, LI Yu, ZHANG Xiangyang. Correlation of Metabolic Indexes as Predictors with Obstructive Sleep Apnea [J]. Chinese General Practice, 2023, 26(30): 3740-3747.
[14]	HU Jiayu, REN Lijue, JIN Huanhuan, SUN Tingting, JIN Meina, ZHOU Xueli, WEI Cuiying. The Level of Adipokine Metrnl and Its Relationship with Inflammation and Insulin Resistance in Patients with Obstructive Sleep Apnea Syndrome [J]. Chinese General Practice, 2023, 26(30): 3748-3752.
[15]	ZHU Lin, GUO Yankui, GAO Chen, CHEN Xuezhi, WANG Fashuai. Efficacy of Western Medicine, Chinese Patent Medicine and Their Combination on Post-stroke Insomnia: a Network Meta-analysis [J]. Chinese General Practice, 2023, 26(30): 3823-3832.