Abstract: Background　Postpartum depression（PPD） is a common mental health problem in parturients.Psychotherapies for PPD includes cognitive behavioral therapy，music therapy，Morita therapy and interpersonal psychotherapy（IPT）．In recent years，IPT focuses on the interpersonal relationship of patients with PPD，and the intervention methods of IPT are simple and easy，so the researches on using IPT to treat PPD are increasing.However，most of the current studies on small sample size are still lacking evidence to prove them.Objective　To explore the efficacy of IPT on patients with PPD by the meta-analysis.Methods　December 2017，Searching on networks and online databases such as PubMed（MEDLINE），EBSCO，EMbase，CNKI，Wan Fang Data，SinoMed and VIP database to collect relative randomized controlled trials（RCTs） in which patients with PPD were treated with IPT.The retrieval time was from the beginning of the database to December 26，2017.The retrieval method was a combination of searching subject term and free words.Strict control was carried out by two researchers to guarantee the quality of references and the eligible RCTs were meta-analyzed.Results　A total of 10 RCTs were included.Edinburgh Postnatal Depression Scale（EPDS），Beck Depression Inventory（BDI） and Hamilton Rating Scale for Depression（HRSD） were used as evaluation indicators to divide 10 RCTs into three groups.When HRSD was used as evaluation criteria，and random effect model was used to include two RCTs，Meta analysis results showed that the total effective rate of the experimental group was higher than that of the control group〔SMD=-6.47，95%CI（-9.92，-3.02），P<0.01〕.When Using BDI and EPDS as evaluation criteria，the meta-analysis results showed that the total effective rate of the experimental group was higher than that of the control group after using the fixed-effect model and sensitivity analysis〔SMD=-1.04，95%CI（-1.21，-0.87），P<0.01〕.Conclusion　IPT has a significant intervention effect on PPD.However，due to the small number of included studies and the wide range of intervention time，more rigorous RCTs are needed in the future.

Key words: Depression, postpartum；Psychotherapy；Cognitive therapy；Interpersonal relations；Meta-analysis

摘要： 背景　产后抑郁是产妇常见的心理健康问题。国内外有关产后抑郁的心理治疗方法包括认知行为疗法、音乐疗法、森田疗法、人际心理疗法（IPT）等。近年来，由于IPT关注产后抑郁女性的人际关系，在治疗产后抑郁方面的研究日益增多。但目前多为小样本的研究，尚缺乏循证依据。目的　通过Meta分析探索IPT对产后抑郁的治疗效果。方法　2017年12月，计算机检索PubMed、EBSCO、EMbase、中国知网、万方数据知识服务平台、中国生物医学文献数据库、维普数据库，搜集IPT治疗产后抑郁的相关随机对照试验（RCT），检索时限为从建库至2017-12-26。检索方式为主题词与自由词结合。由两名研究者对文献质量进行评价和资料提取，对符合质量标准的RCT进行Meta分析。结果　共纳入10篇文献。Meta分析显示，分别以爱丁堡产后抑郁量表（EPDS）、贝克抑郁量表（BDI）、汉密尔顿抑郁量表（HRSD）为评价指标分为3组：以HRSD为评价标准，采用随机效应模型纳入2篇文献后Meta分析结果显示，试验组总有效率高于对照组〔标准化差值（SMD）=-6.47，95%CI（-9.92，-3.02），P<0.01〕。以BDI、EPDS为评价标准，采用固定效应模型，行敏感性分析后Meta分析结果显示，试验组总有效率高于对照组〔SMD=-1.04，95%CI（-1.21，-0.87），P<0.01〕。结论　IPT对PPD具有显著的干预效果。

关键词: 抑郁症, 产后；心理疗法；认知疗法；人际关系；Meta分析