Research Progress on the Relationship between Gut Microbiota and Respiratory Diseases

doi:10.12114/j.issn.1007-9572.2019.00.425

Abstract

Abstract: Gut microbiota interacts with host immune system in ways that influence the process of diseases.Recent evidence suggests that the gut microbiota plays a key role in immune adaptation and immunologic priming in the gastrointestinal tracts as well as other distal mucosal sites，such as the lung.In this review，we highlight the microbial species that are usually found in healthy gastrointestinal and respiratory tracts，their dysbiosis in diseases and interactions with the gut-lung axis with a particular focus on effects of the intestinal microbiota on respiratory diseases.

Key words: Gastrointestinal tract, Gut microbiota, Gut-lung axis, Respiratory system, Lung diseases

摘要： 肠道菌群与宿主免疫系统相互作用，影响疾病的发展。最新的证据表明，肠道菌群在胃肠道以及其他远端黏膜部位（如肺）的免疫适应和启动中起着关键作用。本文重点介绍在健康胃肠道和呼吸道中发现的微生物种类及其在疾病中的失调以及与肠-肺轴的相互作用，尤其是肠道微生物群对呼吸系统疾病的影响。

关键词: 胃肠道, 肠道菌群, 肠-肺轴, 呼吸系统, 肺疾病

ZHANG Litao,ZHAO Jing,HAN Hu. Research Progress on the Relationship between Gut Microbiota and Respiratory Diseases　[J]. Chinese General Practice, 2019, 22(27): 3302-3307. DOI: 10.12114/j.issn.1007-9572.2019.00.425.
张立涛,赵静,韩虎. 肠道菌群与呼吸系统疾病关系的研究进展[J]. 中国全科医学, 2019, 22(27): 3302-3307. DOI: 10.12114/j.issn.1007-9572.2019.00.425.

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