Abstract: Objective　To construct a general practitioners' Knowledge-Attitude-Practice questionnaire（referred as KAP questionnaire）for anticoagulant therapy in patients with non-valvular atrial fibrillation（NVAF），and to lay a foundation for the evaluation of knowledge，attitude and clinical practice among general practitioners in communities in anticoagulation for NVAF patients.Methods　Based on the knowledge-attitude-practice model，an initial KAP questionnaire was formed from October 2017 to January 2018 by searching a large number of domestic and foreign literatures，guidelines for atrial fibrillation（AF）management，and foreign questionnaires about AF.74 entries were divided into three dimensions：knowledge（including entries C1-C24），attitude（including entries D1-D27），and practice（including entries E1-E23）．The Delphi expert consultation questionnaires were sent to expert panel by e-mail.The completion period was 1 week.Two rounds of letter consultation were conducted，with an interval of 4-8 weeks.After the first round consultation，the research group summarized and sorted out expert suggestions，modified the initial KAP questionnaire，and formed the second round consultation.The experts were consulted again，and their opinions tended to be consistent.Their suggestions were summarized and sorted out，and finally KAP questionnaire was determined and formed.Basic information，enthusiasm，suggestion for revisions，degrees of authority，concentration and coordination about experts were recorded in our study.Results　In the first round consultation，15 Delphi expert consultation questionnaires were sent out，and 15 valid questionnaires were collected，with an effective recovery rate of 100.0%.In the second round，15 Delphi questionnaires were sent out，14 valid questionnaires were collected，with an effective recovery rate of 93.3%.The positive coefficient of the expert in the first round consultation was 100.0%，and in the second round consultation was 93.3%.The results of the first round consultation showed that the experts had six suggestions.After the discussion of the research group，C3，C5，C11，C17，C23 and C24 were deleted in the knowledge dimension of initial KAP questionnaire，and other 18 items were saved.D1，D12，D14，D15，D16，D19 and D20 were deleted in the attitude dimension，remaining 21 entries.E3，E6，E8 and E11 were deleted in the behavioral dimension，remaining 19 items.Reserved items were modified according to expert opinions.The results of the second round consultation showed that experts had three suggestions：to merge D6 and D7，D8 and D9，and D22 and D23，adjust initial KAP questionnaire items and delete C22 and E10.The expert authority coefficient（Cr）was 0.87.The concentration degree of expert opinions in the knowledge dimension of initial KAP questionnaire was 3.93 to 4.89 points in the first round consultation，and 4.31 to 4.98 points in the second round consultation.The concentration degree of expert opinions in the attitude dimension was 3.45 to 4.76 points in the first round and 4.19 to 4.94 points in the second round.The concentration degree of expert opinions in the practice dimension was 3.80 to 4.93 points in the first round and 4.15 to 4.91 points in the second round.The coefficient of variation（CV）of knowledge dimension in the initial KAP questionnaire was 0.06 to 0.32 in the first round，and 0.02 to 0.10 in the second round.CV of attitude dimension was 0.09 to 0.47 in the first round，and 0.03 to 0.10 in the second round.CV of practice dimension was 0.04 to 0.38 in the first round and 0.03 to 0.10 in the second round.The W value of first round consultation was 0.221，and significance test χ2 was 241.554，P<0.001.The W value of second round consultation was 0.403，and significance test χ2 was 321.699，P<0.001.Conclusion　The KAP questionnaire constructed in our study includes 3 dimensions of knowledge，attitude and practice，with a total of 52 items.Statistical analysis shows that the positive coefficient and authority of experts are high，the opinions are concentrated，and the results of consultation is scientific，valid and reliable.

Key words: Atrial fibrillation, Anticoagulant therapy, Delphi technique, General practitioners, Knowledge-Attitude-Practice questionnaire

摘要： 目的　构建全科医生对非瓣膜性心房颤动患者抗凝治疗的知信行（KAP）问卷（以下简称KAP问卷）内容，为评价社区全科医生在非瓣膜性心房颤动抗凝治疗方面的知识水平、态度和临床实践奠定基础。方法　2017年10月—2018年1月，以知识-信念-行为模式为理论框架，在查阅大量国内外文献、心房颤动管理相关指南和借鉴国外心房颤动相关问卷的基础上形成初始KAP问卷，其包括74个条目，分为知识（包括条目C1~C24）、态度（条目D1~D27）、行为（包括条目E1~E23）3个维度。采用电子邮件的方式向Delphi专家函询小组发放Delphi专家函询问卷，填写周期为1周，共进行2轮函询，间隔4~8周。第1轮函询后，本课题组将专家建议进行归纳整理，对初始KAP问卷进行修改，形成第2轮函询问卷，再次向专家函询，专家意见趋于一致，将其建议进行归纳整理，最终确定并形成KAP问卷。记录专家基本资料、专家积极性、专家修改建议、专家权威程度、专家意见集中程度、专家意见协调程度。结果　第1轮函询发出15份Delphi专家函询问卷，回收有效问卷15份，有效回收率为100.0%；第2轮函询发出15份Delphi专家函询问卷，回收有效问卷14份，有效回收率为93.3%。第1轮函询的专家积极系数为100.0%，第2轮函询的专家积极系数为93.3%。第1轮函询结果显示，专家有6条建议，经课题组讨论后初始KAP问卷中知识维度删除C3、C5、C11、C17、C23和C24，剩余18个条目；态度维度删除D1、D12、D14、D15、D16、D19和D20，剩余21个条目；行为维度删除E3、E6、E8和E11，剩余19个条目；在保留的条目中，根据专家相关意见进行了内容修改。第2轮函询结果显示，专家有3条建议，分别为合并D6与D7、合并D8与D9、合并D22与D23，并对初始KAP问卷条目进行调整并删除C22和E10。专家权威系数（Cr）=0.87。初始KAP问卷中知识维度的专家意见集中程度第1轮函询为3.93~4.89分，第2轮函询为4.31~4.98分；态度维度的专家意见集中程度第1轮函询为3.45~4.76分，第2轮函询为4.19~4.94分；行为维度的专家意见集中程度第1轮函询为3.80~4.93分，第2轮函询为4.15~4.91分。初始KAP问卷中知识维度的变异系数（CV）第1轮函询为0.06~0.32，第2轮函询为0.02~0.10；态度维度的CV第1轮函询为0.09~0.47，第2轮函询为0.03~0.10；行为维度的CV第1轮函询为0.04~0.38，第2轮函询为0.03~0.10。第1轮函询专家意见的肯德尔协调系数（W）=0.221，显著性检验的χ2=241.554、P<0.001；第2轮函询专家意见的W=0.403，显著性检验的χ2=321.699、P<0.001。结论　本研究构建的KAP问卷包括知识、态度、行为3个维度，共52个条目。且经统计分析，专家积极系数、权威程度较高，意见较集中，函询结果科学性、可信度和可靠性高。

关键词: 心房颤动, 抗凝治疗, 德尔菲技术, 全科医生, 知信行问卷