关键词: 1 型糖尿病, 维生素D, 糖尿病并发症

Abstract: Type 1 diabetes mellitus (Type 1 Diabetes Mellitus,T1DM) is a chronic autoimmune disease caused by pancreatic β-cell destruction；mainly due to a combination of genetic and environmental factors；resulting in the destruction of pancreatic β-cells；which leads to absolute deficiency of insulin secretion and lifelong dependence on extracorporeal insulin therapy.With the increasing incidence of T1DM worldwide；more attention is paid to the prevention and treatment of T1DM.Many studies have demonstrated the importance of vitamin D in the development and progression of chronic inflammatory and immune-related diseases；in addition to its significant value in bone metabolism and calcium and phosphorus homeostasis；Studies have shown that vitamin D is not only valuable for bone metabolism and calcium-phosphorus balance；but also plays an important role in the development and progression of chronic inflammatory and immune-related diseases. Therefore，based on the epidemiology of T1DM and the role of vitamin D， this article further describes the correlation between vitamin D and T1DM and its complications，with the aim of providing a theoretical basis for clinicians to comprehensively diagnose and treat T1DM.

Key words: Type 1 diabetes mellitus, Vitamin D, Diabetes complications