中国全科医学 ›› 2025, Vol. 28 ›› Issue (03): 358-364.DOI: 10.12114/j.issn.1007-9572.2024.0193

• 论著·儿童健康专题研究 • 上一篇    下一篇

童年逆境与成年期高血压患病的研究进展

姜申1,2, 吴静1, 周佳丽1, 蒋德楠1, 孙炜迪1, 程思清1, 朱思雨1, 侯乐莹1, 宋培歌1,3,*()   

  1. 1.310058 浙江省杭州市,浙江大学公共卫生学院
    2.365500 福建省三明市疾病预防控制中心免疫规划科
    3.310006 浙江省杭州市,浙江大学医学院附属第二医院临床大数据与统计中心
  • 收稿日期:2024-05-20 修回日期:2024-07-10 出版日期:2025-01-20 发布日期:2024-10-28
  • 通讯作者: 宋培歌

  • 作者贡献:

    姜申、宋培歌负责文章的选题、构思与设计;姜申进行文献及资料的检索、收集与整理,并撰写论文;吴静、周佳丽、蒋德楠、孙炜迪、程思清、朱思雨、侯乐莹进行论文的修订;宋培歌负责文章的质量控制和审校,对文章整体负责。

Progress in the Study of the Association between Adverse Childhood Experiences and the Prevalence of Hypertension in Adulthood

JIANG Shen1,2, WU Jing1, ZHOU Jiali1, JIANG Denan1, SUN Weidi1, CHENG Siqing1, ZHU Siyu1, HOU Leying1, SONG Peige1,3,*()   

  1. 1. School of Public Health, Zhejiang University, Hangzhou 310058, China
    2. Department of Immunization Program, Sanming Center for Disease Control and Prevention, Sanming 365500, China
    3. Center of Clinical Big Data and Analytics, the Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou 310006, China
  • Received:2024-05-20 Revised:2024-07-10 Published:2025-01-20 Online:2024-10-28
  • Contact: SONG Peige

摘要: 童年逆境(ACEs)是指发生在儿童时期(18岁以前)的各种创伤事件或情况。长期并持续的ACEs可能对儿童身心健康造成终身影响。目前,欧美地区的多项研究证实了ACEs可增加个体成年期高血压的患病风险,然而不同分型的ACEs与成年期高血压的关联仍存在争议。本文对不同分型的ACEs与成年期高血压相关研究进行综述,探讨童年期不同分型逆境对成年期高血压患病的影响及其发生、发展机制,归纳总结两者间的研究现状并提出展望,为改善儿童早期发展环境、预防其成年期高血压研究提供依据。

关键词: 童年不良经历, 童年逆境, 成年期高血压, 高血压, 疾病负担, 综述

Abstract:

Adverse childhood experiences (ACEs) are traumatic events or situations that individuals may experience during their childhood. Children living with prolonged and persistent adverse experiences may have lifelong effects on their physical and mental health. Most studies in Europe and the United States confirm that ACEs increase the risk of hypertension in adulthood. However, the association between different types of ACEs and hypertension in adulthood remains controversial. This study provides a comprehensive review of studies on the association between different types of ACEs and hypertension, which explores the effects of ACEs on hypertension in adulthood and potential mechanisms. This study also summarizes the current status of studies on ACEs and hypertension. It presents a prospective view of providing a basis for improving the early childhood developmental environment and preventing hypertension in adulthood.

Key words: Adverse childhood experiences, Adverse childhood experiences, Hypertension in adulthood, Hypertension, Burden of disease, Review

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