[1] |
|
[2] |
MEZEY É, PALKOVITS M. Neuroanatomy:Forgotten findings of brain lymphatics[J]. Nature, 2015, 524(7566):415. DOI: 10.1038/524415b.
|
[3] |
ILIFF J J, WANG M H, LIAO Y H,et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes,including amyloid Β[J]. Sci Transl Med, 2012, 4(147):147ra111. DOI: 10.1126/scitranslmed.3003748.
|
[4] |
ACHARIYAR T M, LI B M, PENG W G,et al. Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation[J]. Mol Neurodegener, 2016, 11(1):74. DOI: 10.1186/s13024-016-0138-8.
|
[5] |
LUNDGAARD I, LI B M, XIE L L,et al. Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism[J]. Nat Commun, 2015, 6:6807. DOI: 10.1038/ncomms7807.
|
[6] |
HARRISON I F, ISMAIL O, MACHHADA A,et al. Impaired glymphatic function and clearance of tau in an Alzheimer's disease model[J]. Brain, 2020, 143(8):2576-2593. DOI: 10.1093/brain/awaa179.
|
[7] |
SUNDARAM S, HUGHES R L, PETERSON E,et al. Establishing a framework for neuropathological correlates and glymphatic system functioning in Parkinson's disease[J]. Neurosci Biobehav Rev, 2019, 103:305-315. DOI: 10.1016/j.neubiorev.2019.05.016.
|
[8] |
TOH C H, SIOW T Y. Glymphatic dysfunction in patients with ischemic stroke[J]. Front Aging Neurosci, 2021, 13:756249. DOI: 10.3389/fnagi.2021.756249.
|
[9] |
SULLAN M J, ASKEN B M, JAFFEE M S,et al. Glymphatic system disruption as a mediator of brain trauma and chronic traumatic encephalopathy[J]. Neurosci Biobehav Rev, 2018, 84:316-324. DOI: 10.1016/j.neubiorev.2017.08.016.
|
[10] |
ZHANG R, LIU Y, CHEN Y,et al. Aquaporin 4 deletion exacerbates brain impairments in a mouse model of chronic sleep disruption[J]. CNS Neurosci Ther, 2020, 26(2):228-239. DOI: 10.1111/cns.13194.
|
[11] |
XIA M S, YANG L, SUN G F,et al. Mechanism of depression as a risk factor in the development of Alzheimer's disease:the function of AQP4 and the glymphatic system[J]. Psychopharmacology (Berl), 2017, 234(3):365-379. DOI: 10.1007/s00213-016-4473-9.
|
[12] |
REEVES B C, KARIMY J K, KUNDISHORA A J,et al. Glymphatic system impairment in Alzheimer's disease and idiopathic normal pressure hydrocephalus[J]. Trends Mol Med, 2020, 26(3):285-295. DOI: 10.1016/j.molmed.2019.11.008.
|
[13] |
SYKOVÁ E, NICHOLSON C. Diffusion in brain extracellular space[J]. Physiol Rev, 2008, 88(4):1277-1340. DOI: 10.1152/physrev.00027.2007.
|
[14] |
ORESKOVIC D, KLARICA M. The formation of cerebrospinal fluid:nearly a hundred years of interpretations and misinterpretations[J]. Brain Res Rev, 2010, 64(2):241-262. DOI: 10.1016/j.brainresrev.2010.04.006.
|
[15] |
FÖLDI M, CSILLIK B, VÁRKONYI T,et al. Lymphostatic cerebral hemangiopathy. Ultrastructural alteraions in bloodcapillaries of the brain after blockade of crical lymph drainage[J]. Vasc Surg, 1968, 2(4):214-222. DOI: 10.1177/153857446800200405.
|
[16] |
CASLEY-SMITH J R, FÖLDI-BÖRCSÖK E, FÖLDI M. Fine structural aspects of lymphoedema in various tissues and the effects of treatment with coumarin and troxerutin[J]. Br J Exp Pathol,1974,55(1):88-93.
|
[17] |
BRESLIN J W, YANG Y, SCALLAN J P,et al. Lymphatic vessel network structure and physiology[J]. Compr Physiol, 2018, 9(1):207-299. DOI: 10.1002/cphy.c180015.
|
[18] |
LI J, ZHOU J, SHI Y. Scanning electron microscopy of human cerebral meningeal stomata[J]. Ann Anat, 1996, 178(3):259-261. DOI: 10.1016/S0940-9602(96)80059-8.
|
[19] |
ZERVAS N T, LISZCZAK T M, MAYBERG M R,et al. Cerebrospinal fluid may nourish cerebral vessels through pathways in the adventitia that may be analogous to systemic Vasa vasorum[J]. J Neurosurg, 1982, 56(4):475-481. DOI: 10.3171/jns.1982.56.4.0475.
|
[20] |
LOUVEAU A, SMIRNOV I, KEYES T J,et al. Structural and functional features of central nervous system lymphatic vessels[J]. Nature, 2015, 523(7560):337-341. DOI: 10.1038/nature14432.
|
[21] |
ABSINTA M, HA S K, NAIR G,et al. Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI[J]. Elife, 2017, 6:e29738. DOI: 10.7554/eLife.29738.
|
[22] |
XIE L L, KANG H Y, XU Q W,et al. Sleep drives metabolite clearance from the adult brain[J]. Science, 2013, 342(6156):373-377. DOI: 10.1126/science.1241224.
|
[23] |
HABLITZ L M, PLÁ V, GIANNETTO M,et al. Circadian control of brain glymphatic and lymphatic fluid flow[J]. Nat Commun, 2020, 11(1):4411. DOI: 10.1038/s41467-020-18115-2.
|
[24] |
MESTRE H, HABLITZ L M, XAVIER A L,et al. Aquaporin-4-dependent glymphatic solute transport in the rodent brain[J]. Elife, 2018, 7:e40070. DOI: 10.7554/eLife.40070.
|
[25] |
ILIFF J J, WANG M H, ZEPPENFELD D M,et al. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain[J]. J Neurosci, 2013, 33(46):18190-18199. DOI: 10.1523/JNEUROSCI.1592-13.2013.
|
[26] |
KRESS B T, ILIFF J J, XIA M S,et al. Impairment of paravascular clearance pathways in the aging brain[J]. Ann Neurol, 2014, 76(6):845-861. DOI: 10.1002/ana.24271.
|
[27] |
RASMUSSEN M K, MESTRE H, NEDERGAARD M. The glymphatic pathway in neurological disorders[J]. Lancet Neurol, 2018, 17(11):1016-1024. DOI: 10.1016/S1474-4422(18)30318-1.
|
[28] |
GAKUBA C, GABEREL T, GOURSAUD S,et al. General anesthesia inhibits the activity of the "glymphatic system" [J]. Theranostics, 2018, 8(3):710-722. DOI: 10.7150/thno.19154.
|
[29] |
HARRISON I F, ISMAIL O, MACHHADA A,et al. Impaired glymphatic function and clearance of tau in an Alzheimer's disease model[J]. Brain, 2020, 143(8):2576-2593. DOI: 10.1093/brain/awaa179.
|
[30] |
MCKNIGHT C D, TRUJILLO P, LOPEZ A M,et al. Diffusion along perivascular spaces reveals evidence supportive of glymphatic function impairment in Parkinson disease[J]. Parkinsonism Relat Disord, 2021, 89:98-104. DOI: 10.1016/j.parkreldis.2021.06.004.
|
[31] |
SUNDARAM S, HUGHES R L, PETERSON E,et al. Establishing a framework for neuropathological correlates and glymphatic system functioning in Parkinson's disease[J]. Neurosci Biobehav Rev, 2019, 103:305-315. DOI: 10.1016/j.neubiorev.2019.05.016.
|
[32] |
PENG W G, ACHARIYAR T M, LI B M,et al. Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease[J]. Neurobiol Dis, 2016, 93:215-225. DOI: 10.1016/j.nbd.2016.05.015.
|
[33] |
REN H X, LUO C M, FENG Y Q,et al. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system[J]. FASEB J, 2017, 31(1):282-293. DOI: 10.1096/fj.201600896.
|
[34] |
YIN M M, PU T L, WANG L M,et al. Astroglial water channel aquaporin 4-mediated glymphatic clearance function:a determined factor for time-sensitive treatment of aerobic exercise in patients with Alzheimer's disease[J]. Med Hypotheses, 2018, 119:18-21. DOI: 10.1016/j.mehy.2018.07.016.
|
[35] |
CAO J, YAO D, LI R,et al. Digoxin ameliorates glymphatic transport and cognitive impairment in a mouse model of chronic cerebral hypoperfusion[J]. Neurosci Bull, 2022, 38(2):181-199. DOI: 10.1007/s12264-021-00772-y.
|
[36] |
LI L, CHOPP M, DING G L,et al. MRI detection of impairment of glymphatic function in rat after mild traumatic brain injury[J]. Brain Res, 2020, 1747:147062. DOI: 10.1016/j.brainres.2020.147062.
|
[37] |
BOLTE A C, DUTTA A B, HURT M E,et al. Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis[J]. Nat Commun, 2020, 11(1):4524. DOI: 10.1038/s41467-020-18113-4.
|
[38] |
JONES O, CUTSFORTH-GREGORY J, CHEN J,et al. Idiopathic intracranial hypertension is associated with a higher burden of visible cerebral perivascular spaces:the glymphatic connection[J]. AJNR, 2021, 42(12):2160-2164. DOI: 10.3174/ajnr.A7326.
|
[39] |
MONDEJAR V, PATSALIDES A. The role of arachnoid granulations and the glymphatic system in the pathophysiology of idiopathic intracranial hypertension[J]. Curr Neurol Neurosci Rep, 2020, 20(7):20. DOI: 10.1007/s11910-020-01044-4.
|
[40] |
WANG X W, LOU N H, EBERHARDT A,et al. An ocular glymphatic clearance system removes β-amyloid from the rodent eye[J]. Sci Transl Med, 2020, 12(536):eaaw3210. DOI: 10.1126/scitranslmed.aaw3210.
|
[41] |
ZHAO P F, LE Z C, LIU L X,et al. Therapeutic delivery to the brain via the lymphatic vasculature[J]. Nano Lett, 2020, 20(7):5415-5420. DOI: 10.1021/acs.nanolett.0c01806.
|