中国全科医学 ›› 2021, Vol. 24 ›› Issue (21): 2634-2639.DOI: 10.12114/j.issn.1007-9572.2021.00.550

• 专题研究 • 上一篇    下一篇

溃疡性结肠炎疾病活动病理组织学评价指标的应用现状

彭颖1,徐丽红1,2*   

  1. 1.832000新疆石河子市,石河子大学医学院 
    2.611130四川省成都市,成都中医药大学附属第五人民医院消化内科
    *通信作者:徐丽红,硕士生导师;E-mail:xueli_2006@126.com
  • 出版日期:2021-07-20 发布日期:2021-07-20
  • 基金资助:
    基金项目:国家自然科学基金资助项目(81660095)

Application of Histopathological Disease Activity Indices in Ulcerative Colitis 

PENG Ying1,XU Lihong1,2*   

  1. 1.Shihezi University School of Medicine,Shihezi 832000,China
    2.Department of Gastroenterology,Affiliated Fifth People's Hospital of Chengdu University of TCM,Chengdu 611130,China
    *Corresponding author:XU Lihong,Master supervisor;E-mail:xueli_2006@126.com
  • Published:2021-07-20 Online:2021-07-20

摘要: 目前,显微镜下肠黏膜病理组织学缓解作为评估溃疡性结肠炎(UC)治疗疗效及患者预后的指标已被广泛认可。现有多种评分系统可用于评估UC患者肠黏膜病理组织学状况,但哪一种评分系统能更准确地反映UC患者的疾病状态,能更准确地判断UC患者的预后,评估结论的一致性更好,尚存在争议。针对这一问题,本文就目前常用的评估UC疾病活动的病理组织学评价指标进行综述,旨在为临床医生准确判断UC患者的疾病状态及疾病转归提供帮助。

关键词: 溃疡性结肠炎, 显微镜检查, 肠黏膜, 病理学, 组织学

Abstract: At present,the histopathological remission of the intestinal mucosa under the microscope has been widely recognized as a means for evaluating the efficacy and prognosis of ulcerative colitis (UC).There are a variety of scoring systems that can be used to assess the histopathological status of the intestinal mucosa of UC patients,but it is still controversial that which one is superior to the other in terms of accurately assessing the disease activity and prognosis,and obtaining higher consensus.On this issue,this article reviews the histopathological disease activity indices commonly used in UC,aiming to provide help for clinicians to accurately determine the disease activity and outcome of UC patients.

Key words: Colitis, ulcerative;Microscopy;Intestinal mucosa;Pathology;Histology