关键词: 结直肠肿瘤, 疾病获益感, 影响因素, 横断面研究

Abstract: Background　With the development of biopsychosocial approach used in medicine，the role of psychological factors in cancer rehabilitation has been widely concerned.Benefit finding（BF） is a key research area in positive psychology，mostly focusing on patients with breast cancer or multiple cancers，rarely involving those with colorectal cancer.Objective　To assess BF and associated factors in early-stage colorectal cancer patients in China.Methods　This study is a cross-sectional study.By convenient sampling method，326 early-stage colorectal cancer inpatients were recruited from two hospitals（Jiangyin People's Hospital and Nantong Tumor Hospital） in Jiangsu to attend a questionnaire survey.Measurement instruments include General Information Questionnaire，Chinese version of Benefit Finding Scale（evaluating benefit finding），Chinese version of Communication with Doctors Questionnaire（evaluating communication with doctors），Hospital Anxiety and Depression Scale（evaluating anxiety and depression），Revised Life Orientation Test（evaluating optimism） and Medical Coping Modes Questionnaire（evaluating the response characteristics of the disease，including facing，avoiding and yielding）.Logistic regression analysis was employed to identify the independent influencing factors of BF.Results　According to the Chinese version of disease benefit scale，patients with early colorectal cancer were divided into low BF level group 31 cases（9.5%，score <66 points），and 295 cases （90.5%，score≥66 points） in medium / high level group.Compared with moderate/high BF group，low BF group had lower prevalence of receiving surgery plus chemotherapy，and lower mean scores of Chinese version of Communication with Doctors Questionnaire and confrontation subscale of Medical Coping Modes Questionnaire as well as lower mean level of optimism（P<0.05）.Moreover，low BF group showed higher mean scores of Hospital Anxiety and Depression Scale and avoidance subscale of Medical Coping Modes Questionnaire and higher incidence of complications（P<0.05）.There were also significant differences in exercise frequency between the two groups（P<0.05）.Logistic regression analysis showed that surgery plus chemotherapy〔OR=3.294，95%CI（1.239，8.759）〕，no complications〔OR=5.867，95%CI（1.868，19.041）〕，optimism〔OR=1.569，95%CI（1.169，2.106）〕，confrontation coping 〔OR=1.477，95%CI（1.267，1.721）〕 were independently associated with BF（P<0.05）.Conclusion　Early-stage colorectal cancer patients in Nantong and Jiangyin had moderate/high BF on the whole.BF was significantly affected by confrontation coping，optimism，surgery plus chemotherapy and no complications.To improve the BF of these patients，frontline physicians and nurses may formulate and implement multidisciplinary and multi-platform intervention programs based on these associated factors of BF.

Key words: Colorectal neoplasms, Benefit finding, Influencing factors, Cross-sectional studies