关键词: 寻常痤疮, 青春期, 埋线, 针灸疗法, 卫气, 疗效比较研究

Abstract: Background　Acne is a chronic inflammatory disease of the hair follicle sebaceous glands that is common in adolescence.There are many female patients after puberty，and the rash lasts for a long time，which seriously affects the appearance and health of the patient.Conventional catgut embedding has a good effect on postpubertal acne in women，and smooth catgut embedding is a method of catgut embedding based on the theory of superficial fascia.At present，there is no comparison of the efficacy of two methods of catgut embedding.Objective　To explore the efficacy and mechanism of different facial catgut embedding methods combined with comprehensive acupuncture therapy on adult female acne.Methods　Sixty-one female patients with adult acne were enrolled from acupuncture clinics of the First People's Hospital of Lianyungang from July 2015 to July 2017.They were divided into smooth catgut embedding group（31 cases） and conventional catgut embedding group（30 cases）．Both groups had comprehensive acupuncture therapy.In smooth catgut embedding group，smooth catgut was embedded in face one week after two times of body acupoints embedment.In conventional catgut embedding group，catgut was embedded in face one and seven weeks after two times of body acupoints embedment.Both groups were intervened for 8 weeks as one course.After 12 weeks，the efficacy for acne skin lesions and accompanying symptoms，scores of acne skin lesions and accompanying symptoms and adverse effects were assessed in both groups.Results　The efficacy for acne skin lesions and accompanying symptoms in smooth catgut embedding group was significantly better than that of conventional catgut embedding group（P<0.05）．There were no significant differences in acne lesion score and accompanying symptom score between two groups before and after treatment（P>0.05）．The acne lesion score and accompanying symptom score after treatment were lower than those before treatment in the two groups（P<0.05）.There were no obvious adverse effects in both groups.Conclusion　Different facial catgut embedding methods combined with comprehensive acupuncture therapy has better clinical efficacy on acne lesions and accompanying symptoms in adult female acnes.The mechanism of facial catgut embedding is closely related to the theories of meridians，superficial fascia and defensive Qi.Smooth catgut embedding has less painful than routine catgut embedding and has better wrinkle improvement effect.Therefore，smooth catgut embedding is superior to routine catgut embedding，which is worthy of clinical popularization and application.

Key words: Acne vulgaris；Puberty；Embedding, thread；Acupuncture-moxibustion；Defensive energy；Comparative effectiveness research