关键词: 肝炎, 慢性；生活质量；量表；文献计量法

Abstract: Objective　To analyze the application of health-related quality of life（HRQOL） instruments in chronic hepatitis patients，providing a reference for quality of life assessment including the choice of an appropriate instrument in such a population in China.Methods　From March to September 2017，we searched the databases of CNKI，Wanfang Data Knowledge Service Platform，VIP and CBM，to identify the articles about HRQOL assessment.We analyzed the included articles by general information and contents of article，type of used HRQOL instrument and so on.Results　A total of 233 articles were included，including 221 journal articles and 12 conference articles.Except those using instruments developed by the undetermined developer，among the remaining articles，the using times of general HRQOL instruments，chronic hepatitis-specific HRQOL instruments，and mental health assessment instruments developed in foreign countries were 150（75.76%），42（65.63%），92（95.83%），respectively，while those of the aforementioned 3 types of instruments developed in China were 37（18.67%），10（15.63%），0，respectively.158 articles（67.81%） used 1 type of HRQOL instrument〔including 124（78.48%），17（10.76%），17（10.76%） using the general HRQOL instrument and chronic hepatitis-specific HRQOL instrument，mental health assessment instrument，respectively〕，most of which used SF-36，CLDQ or SAS+SDS.Seventy-one（30.47%）used 2 types of HRQOL instruments，and most of which used SF-36/WHOQOL-BREF+CLDQ，SF-36/WHOQOL-BREF/GQOLI-74+SAS/SDS，or CLDQ+SAS/SDS.Four（1.72%） used 3 types of HRQOL instruments of WHOQOL-BREF+CLDQ/SDSS/medication adherence scale+SAS/SDS.Conclusion　For assessing HRQOL of chronic hepatitis patients，most articles published in China use foreign instruments，and domestic instruments need to be further developed and used extensively by which more choice can be offered for such studies.

Key words: Hepatitis, chronic；Quality of life；Assessment instruments；Bibliometrics