关键词: 脑损伤, 乙醇, 预后, 影响因素分析

Abstract: Objective　To assess the effect of blood alcohol level（BAL） on the forecasting prognosis of patients with mild traumatic brain injury（mTBI） after drinking.Methods　A retrospective analysis of 58 patients with mTBI after drinking admitted to the Department of Emergency，Wujin Hospital of Traditional Chinese Medicine，Nanjing University of Chinese Medicine from July 2016 to September 2017 was conducted.Subjects were divided into the drinking group（BAL<80 mg/dl，33 cases） and the intoxicated group（BAL≥80 mg/dl，25 cases）.The general data of patients admitted to the hospital were collected.Wechsler Adult Intelligence Scale（WAIS） was used to evaluate patients' non-verbal processing speed，and Glasgow Prognostic Expansion Scale（GOS-E） used to evaluate prognosis after 3 months of discharge.Results　There were significant differences in palinesthesia time，Glasgow Coma Scale（GCS） score and time of consciousness loss between the two groups on admission（P<0.05）.The non-verbal processing speed score of WAIS in the intoxicated group was（102.4±12.3），higher than that of the drinking group（93.6±12.7）（t=2.518，P=0.014） after 3 months.Fifty-five cases completed the GOS-E assessment and 11 of them（20.0%） had a poor prognosis.Multivariate Logistic regression analysis showed that GCS scores being 13-14 on admission 〔OR=3.93，95%CI（2.23，7.19）〕 and BAL≥80 mg/dl 〔OR=4.67，95%CI（1.08，5.46）〕 were influencing factors of poor prognosis of patients with mTBI（P<0.05）.Conclusion　Patients whose BAL are ≥80 mg/dl has decreased GCS score and increased risk of loss of consciousness，and a high risk of reducing non-verbal processing speed and inadequate recovery of cognitive function after 3 months' injury.

Key words: Brain injuries, Ethanol, Prognosis, Root cause analysis